Detalhe da pesquisa
1.
A phase 1 study to evaluate the safety, pharmacology, and feasibility of continuous infusion nelarabine in patients with relapsed and/or refractory lymphoid malignancies.
Cancer
; 129(4): 580-589, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36448227
2.
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Haematologica
; 106(2): 495-512, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029507
3.
Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.
Br J Haematol
; 179(2): 266-271, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737232
4.
Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
Blood
; 123(24): 3780-9, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747434
5.
Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia.
Front Oncol
; 13: 1161254, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37228498
6.
DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia.
Blood Adv
; 7(21): 6685-6701, 2023 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37648673
7.
Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
Blood
; 116(7): 1083-91, 2010 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20442367
8.
8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma.
Blood
; 116(25): 5622-30, 2010 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20844237
9.
Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.
Front Oncol
; 12: 833714, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35273915
10.
Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19.
Antiviral Res
; 206: 105403, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041646
11.
Pirtobrutinib inhibits wild-type and mutant Bruton's tyrosine kinase-mediated signaling in chronic lymphocytic leukemia.
Blood Cancer J
; 12(5): 80, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595730
12.
Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
Mol Cancer Res
; 20(2): 280-292, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34654720
13.
Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels.
J Biol Chem
; 285(11): 8022-30, 2010 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064937
14.
A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels.
Breast Cancer Res Treat
; 121(2): 355-64, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19641990
15.
Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival.
Clin Cancer Res
; 15(5): 1762-9, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19240178
16.
AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia.
Clin Cancer Res
; 26(14): 3856-3867, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31937611
17.
Ex Vivo Pharmacological Profiling in Chronic Lymphocytic Leukemia Cells.
Methods Mol Biol
; 1881: 19-25, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30350194
18.
PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells.
Oncotarget
; 10(29): 2793-2809, 2019 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31073371
19.
Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells.
Oncotarget
; 9(38): 24980-24991, 2018 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29861847
20.
Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells.
Clin Cancer Res
; 23(14): 3734-3743, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28034907