Detalhe da pesquisa
1.
Novel NRF2-activated cancer treatments utilizing synthetic lethality.
IUBMB Life
; 74(12): 1209-1231, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36200139
2.
Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system.
Genes Cells
; 20(7): 563-77, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940588
3.
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex.
Proc Natl Acad Sci U S A
; 110(38): 15259-64, 2013 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23986495
4.
The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics.
Biochem Soc Trans
; 43(4): 602-10, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551700
5.
Hypoxia-sensitive reporter system for high-throughput screening.
Tohoku J Exp Med
; 235(2): 151-9, 2015 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746387
6.
Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals.
J Biochem
; 175(6): 611-627, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38268329
7.
Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Biochem Biophys Res Commun
; 433(1): 58-65, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23454126
8.
Immunoediting of KEAP1-NRF2 mutant tumours is required to circumvent NRF2-mediated immune surveillance.
Redox Biol
; 67: 102904, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37839356
9.
A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells.
Redox Biol
; 66: 102845, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37597423
10.
Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity.
Free Radic Biol Med
; 187: 92-104, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618180
11.
The cytoprotective role of the Keap1-Nrf2 pathway.
Arch Toxicol
; 85(4): 241-72, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21365312
12.
NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer.
Mol Cell Biol
; 41(2)2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139492
13.
The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.
Mol Cell Biol
; 40(13)2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32284348
14.
Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2.
Mol Cell Biol
; 40(22)2020 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868290
15.
Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.
Cell Rep
; 28(3): 746-758.e4, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31315052
16.
A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways.
Mol Cell Biol
; 37(4)2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27920251
17.
Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.
Nat Commun
; 8: 14577, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233855
18.
Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.
Mol Cell Biol
; 36(24): 3100-3112, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697860
19.
NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth.
Cancer Res
; 76(10): 3088-96, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27020858
20.
Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.
Mol Cell Biol
; 36(2): 271-84, 2016 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26527616