Detalhe da pesquisa
1.
The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions.
J Biol Chem
; 289(36): 25041-53, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25028517
2.
'Naked' and hydrated conformers of the conserved core pentasaccharide of N-linked glycoproteins and its building blocks.
J Am Chem Soc
; 135(45): 16895-903, 2013 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127839
3.
Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis.
Nat Chem Biol
; 7(4): 228-35, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21378984
4.
Substrate and metal ion promiscuity in mannosylglycerate synthase.
J Biol Chem
; 286(17): 15155-64, 2011 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21288903
5.
Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody-Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer.
Mol Cancer Ther
; 21(9): 1439-1448, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793464
6.
ESI-MS assay of M. tuberculosis cell wall antigen 85 enzymes permits substrate profiling and design of a mechanism-based inhibitor.
J Am Chem Soc
; 133(34): 13232-5, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21776980
7.
Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography - high resolution mass spectrometry.
J Pharm Biomed Anal
; 205: 114287, 2021 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385015
8.
Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual ß-glucuronide and dipeptide triggers.
Eur J Med Chem
; 179: 591-607, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31279293
9.
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
PLoS Negl Trop Dis
; 13(5): e0007373, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31120889
10.
Total synthesis of the marine natural product (-)-clavosolide A.
Org Lett
; 8(15): 3319-22, 2006 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16836395
11.
Stereoselective synthesis of the tetrahydropyran core of polycarvernoside A.
Org Lett
; 7(13): 2683-6, 2005 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15957921
12.
Total synthesis of a diastereomer of the marine natural product clavosolide A.
Chem Commun (Camb)
; (40): 5097-9, 2005 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16220183
13.
Probing the mechanism of Prins cyclisations and application to the synthesis of 4-hydroxytetrahydropyrans.
Chem Commun (Camb)
; (29): 3727-9, 2005 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16027925
14.
Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors.
Angew Chem Int Ed Engl
; 49(7): 1234-7, 2010 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20077550
15.
Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar.
Chem Sci
; 4(9): 3442-3446, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31031905