Social Adversity Reduces Polygenic Score Expressivity for General Cognitive Ability, but Not Height.

It has been hypothesized that even 'perfect' polygenic scores (PGSs) composed of only causal variants may not be fully portable between different social groups owing to gene-by-environment interactions modifying the expression of relevant variants. The impacts of such interactions involving two forms of social adversity (low socioeconomic status [SES] and discrimination) are examined in relation to the expressivity of a PGS for educational attainment composed of putatively causal variants in a large, representatively sampled and genotyped cohort of US children. A relatively small-magnitude Scarr-Rowe effect is present (SES × PGSEDU predicting General Cognitive Ability [GCA]; sR = .02, 95% CI [.00, .04]), as is a distinct discrimination × PGSEDU interaction predicting GCA (sR = -.02, 95% CI [-.05, 00]). Both are independent of the confounding main effects of 10 ancestral principal components, PGSEDU, SES, discrimination and interactions among these factors. No sex differences were found. These interactions were examined in relation to phenotypic and genotypic data on height, a prospectively more socially neutral trait. They were absent in both cases. The discrimination × PGSEDU interaction is a co-moderator of the differences posited in modern versions of Spearman's hypothesis (along with shared environmentality), lending support to certain environmental explanations of those differences. Behavior-genetic analysis of self-reported discrimination indicates that it is nonsignificantly heritable (h2 = .027, 95% CI [-.05, .10]), meaning that it is not merely proxying some underlying source of heritable phenotypic variability. This suggests that experiences of discrimination might stem instead from the action of purely social forces.

Maternal Depression and Child and Adolescent Problem Behaviors: a Propensity Score Matching Approach.

Prior studies have consistently revealed that maternal depression is significantly associated with children exhibiting higher levels of internalizing problem behaviors and externalizing problem behaviors. However, there is reason to believe that prior research may have suffered from model misspecification and confounding that biased the conclusions drawn from these studies. We use this possibility as the foundation for our analyses that examine the potential association between maternal depression and child internalizing and externalizing problem behaviors while addressing the methodological limitations of previous research. To do so, we analyzed data from the National Survey of Child and Adolescent Well-Being and used propensity score matching. The analyses revealed significant differences between depressed and non-depressed mothers that, once accounted for, significantly impacted the revealed associations between maternal depression and child internalizing and externalizing problem behaviors. Although the significant relationship with child internalizing problem behaviors remained in all of the cross-sectional and longitudinal models post-matching, once the mothers were properly matched, the significant relationship between maternal depression and child externalizing problem behaviors disappeared at Wave 3. We conclude by discussing the implications and limitations of our study as well as considerations for future research.

Physical attractiveness and criminal justice processing: results from a longitudinal sample of youth and young adults.

A substantial body of research examining the role that attractiveness plays in a wide range of outcomes has revealed that attractiveness is a beneficial characteristic across multiple domains of life, including some related to crime and the criminal justice system. The current study uses these findings as a springboard to examine the potential association between attractiveness and multiple measures of criminal justice processing, including being arrested, being convicted, being sentenced to probation and being incarcerated. Analysis of data drawn from the National Longitudinal Study of Adolescent to Adult Health revealed that more attractive persons were less likely to be arrested and convicted than less attractive persons, but there was no association with odds of being sentenced to probation or incarcerated. Follow-up analyses revealed that the beneficial effect of being attractive was confined solely to females. We discuss possible reasons for these results and provide suggestions for future research.

Learning to blast a way into crime, or just good clean fun? Examining aggressive play with toy weapons and its relation with crime.

BACKGROUND: Researchers, such as Bandura, have proposed that children's mere exposure to the use of play weapons encourages deviant displays of aggression, but there is very little research to support this hypothesis of 20 years. AIM: To examine the relationship between amount of weapon play and concurrent aggression as well as later violent juvenile crime, while controlling for other variables possibly influencing criminal pathways. METHOD: Using longitudinal survey data collected from mothers and children (n = 2019) from age 5, with follow-up at age 15, correlations between children's play with toy weapons and juvenile criminality were examined. Multivariate regression analyses were employed to determine to what extent early childhood aggression, symptoms of attention deficit hyperactivity disorder, and symptoms of depression were antecedents of juvenile crime. RESULTS: For bivariate analysis between toy weapon play and juvenile criminality, the effect size was small and not significant. The relationship remained not significant once control variables were introduced into the model. CONCLUSIONS AND IMPLICATIONS: The act of pretending to be aggressive in childhood thus plays little role in predicting later criminality after other factors, such as gender, attention deficit hyperactivity disorder or depression, have been taken into account. Involvement in imaginative play with toy gun use in early childhood is unlikely to be useful as a risk marker for later criminal behaviour. Play fighting and war toy games may even be considered necessary components within the frame of normal development. Copyright © 2018 John Wiley & Sons, Ltd.

Integrating Criminological and Mental Health Perspectives on Low Self-Control: A Multi-Domain Analysis.

PURPOSE: Criminological theories of crime, delinquency, and deviancy emphasize the causal role of low self-control whereas models of psychopathology posit a general trait liability, "disinhibition", contributing to persistent antisocial behavior and substance use. The aim of the current work was to link these compatible perspectives on deviancy through reference to a biobehavioral conceptualization of disinhibition. METHODS: We examined how the Grasmick et al. (1993) self-control scale, relates to (a) trait disinhibition as indexed by self-report scales, performance on inhibitory-control tasks, and brain reactivity to cognitive stimuli, and (b) a cross-domain index combining measures from these three domains. RESULTS: As expected, variation in self-control was robustly associated with antisocial deviance, substance use problems, and measures of disinhibition across measurement domains. Further, a factor analytic model provided compelling evidence that the Grasmick et al. scale operates as a robust indicator within a biobehavioral conceptualization of disinhibition. CONCLUSIONS: Findings confirm a strong link between self-control and trait disinhibition, and support the view that deficits in self-control have a prominent biobehavioral basis. Research in the areas of criminology and psychopathology can mutually benefit from a focus on influences contributing to variations in self-control, conceptualized as trait disinhibition.

An Exploration of Mate Similarity for Criminal Offending Behaviors: Results from a Multi-Generation Sample of Dutch Spouses.

There has been a growing body of research examining mate and spousal similarity on antisocial behaviors. The results of these studies have shown varying degrees of similarity between mates and spouses, but the precise mechanisms accounting for such similarity have remained somewhat elusive. The current study builds off this line of research and examines spousal similarity on criminal offending behaviors. Moreover, we also examine the potential factors that might account for spousal similarity. This study analyzed data drawn from two generations of Dutch spouses. The analyses revealed statistically significant associations between mates on criminal offending prior to marriage, a finding that is directly in line with an assortative mating explanation of spousal similarity. In addition, the analyses also revealed that criminal offending between spouses becomes even more similar after marriage, a finding that is line with a behavioral contagion explanation of spousal similarity. We conclude by discussing the limitations of the study along with the implications that these findings have for criminological research.

Sexual Orientation and Involvement in Nonviolent and Violent Delinquent Behaviors: Findings From the National Longitudinal Study of Adolescent to Adult Health.

This study examined the association between sexual orientation and nonviolent and violent delinquency across the life course. We analyzed self-reported nonviolent and violent delinquency in a sample of heterosexual males (N = 5220-7023) and females (N = 5984-7875), bisexuals (N = 34-73), gay males (N = 145-189), and lesbians (N = 115-150) from the National Longitudinal Study of Adolescent to Adult Health (Add Health). The analyses revealed, in general, that bisexuals were the most delinquent of the sexual orientation categories for both males and females. Additional analyses revealed that heterosexual males reported significantly higher levels of both violent and nonviolent delinquency than gay males, whereas lesbians reported more involvement in nonviolent delinquency and, to a lesser extent, violent delinquency relative to heterosexual females. Analyses also revealed that lesbians reported significantly more delinquent behavior, particularly for nonviolent delinquency, than gay males. Future research should explore the mechanisms that account for these observed patterns and how they can be used to more fully understand the etiology of delinquency.

How Cognitive Genetic Factors Influence Fertility Outcomes: A Mediational SEM Analysis.

Utilizing a newly released cognitive Polygenic Score (PGS) from Wave IV of Add Health (n = 1,886), structural equation models (SEMs) examining the relationship between PGS and fertility (which is approximately 50% complete in the present sample), employing measures of verbal IQ and educational attainment as potential mediators, were estimated. The results of indirect pathway models revealed that verbal IQ mediates the positive relationship between PGS and educational attainment, and educational attainment in turn mediates the negative relationship between verbal IQ and a latent fertility measure. The direct path from PGS to fertility was non-significant. The model was robust to controlling for age, sex, and race; furthermore, the results of a multigroup SEM revealed no significant differences in the estimated path coeficients across sex. These results indicate that those predisposed towards higher verbal IQ by virtue of higher PGS values are also predisposed towards trading fertility against time spent in education, which contributes to those with higher PGS values producing fewer offspring at this stage in their life course.

Intelligence and early life mortality: Findings from a longitudinal sample of youth.

The current study examined whether adolescent IQ predicted risk for mortality by the age of 32. Analyses of data from the Add Health revealed that IQ was related to mortality risk, such that respondents with relatively lower IQs were significantly more likely to experience early life mortality when compared to respondents with relatively higher IQs. This association remained statistically significant even after controlling for a host of covariates such as race, gender, involvement in violent behaviors, levels of self-control, and poverty. The average IQ of deceased respondents was approximately 95, whereas the average IQ of living respondents was about 100.

The Association Between Breastfeeding Exposure and Duration, Neuropsychological Deficits, and Psychopathic Personality Traits in Offspring: The Moderating Role of 5HTTLPR.

A wealth of research has revealed that a shorter duration of breastfeeding during infancy can increase the risk of various maladaptive traits, including neuropsychological deficits. Despite the number of studies that have been conducted on the topic, few studies have explored whether the effects of breastfeeding on neuropsychological functioning and personality features persist into adulthood. Furthermore, very little research to date has examined whether this relationship is moderated by specific indicators of genetic risk. The current study examines the direct and interactive effects of breastfeeding experiences and the serotonin transporter polymorphism (5HTTLPR) on neuropsychological deficits and psychopathic personality traits. Using data from the National Longitudinal study of Adolescent Health, we find that no exposure to breastfeeding and a shorter duration of breastfeeding significantly increase the risk of exhibiting neuropsychological deficits during adolescence and early adulthood as well as psychopathic personality traits during adulthood. The results also reveal a number of gene × environment interactions between 5HTTLPR, breastfeeding exposure and breastfeeding duration in the prediction of neuropsychological deficits, but not in the prediction of psychopathic personality traits.

The Association Between Psychopathic Personality Traits and Victimization and Exposure to Violence in a Sample of Saudi Arabian Youth.

Psychopathic personality traits have been shown to increase the odds of a wide range of antisocial outcomes. Very little research, however, has examined the association between psychopathy and the risk of personal victimization. The current study address this gap in the literature by examining the association between scores on the Levenson Self-Report Psychopathy scale and a self-reported measure of victimization by using cross-sectional data drawn from a sample of youth residing in Jeddah, Saudi Arabia (N = 311). The results revealed a positive and statistically significant association between LSPR scores and the odds of being victimized. Additional analyses revealed that two mediators-arrest history and exposure to delinquent peers-were related to personal victimization, but neither of these measures mediated the effects of LSPR scores on victimization. Whether these findings would generalize to other nations remains an issue awaiting future research.

Prenatal Caloric Intake and the Development of Academic Achievement Among U.S. Children From Ages 5 to 14.

Few studies have examined the relation between maternal caloric intake during pregnancy and growth in child academic achievement while controlling for important confounding influences. Using data from the National Longitudinal Survey of Youth, the current study examined the effects of reduced prenatal caloric intake on growth in scores on the Peabody Individual Achievement Test from ages 5 to 14. While models controlling for within-family covariates showed that prenatal caloric intake was associated with lower reading and mathematical achievement at age 5, models controlling for between-family covariates (such as maternal IQ) and unobserved familial confounders revealed only a statistically significant association between siblings differentially exposed to prenatal caloric intake and mathematical achievement at age 5.

Proposing a Pedigree Risk Measurement Strategy: Capturing the Intergenerational Transmission of Antisocial Behavior in a Nationally Representative Sample of Adults.

An impressive literature has revealed that variation in virtually every measurable phenotype is the result of a combination of genetic and environmental influences. Based on these findings, studies that fail to use genetically informed modeling strategies risk model misspecification and biased parameter estimates. Twin- and adoption-based research designs have frequently been used to overcome this limitation. Despite the many advantages of such approaches, many available datasets do not contain samples of twins, siblings or adoptees, making it impossible to utilize these modeling strategies. The current study proposes a measurement strategy for estimating the intergenerational transmission of antisocial behavior (ASB) within a nationally representative sample of singletons using an extended pedigree risk approach that relies on information from first- and second-degree relatives. An evaluation of this approach revealed a pattern of findings that directly aligned with studies examining ASB using more traditional twin- and adoption-based research designs. While the proposed pedigree risk approach is not capable of effectively isolating genetic and environmental influences, this overall alignment in results provides tentative evidence suggesting that the proposed pedigree risk measure effectively captures genetic influences. Future replication studies are necessary as this observation remains preliminary. Whenever possible, more traditional quantitative genetic methodologies should be favored, but the presented strategy remains a viable alternative for more limited samples.

Making (up) the grade? estimating the genetic and environmental influences of discrepancies between self-reported grades and official GPA scores.

Academic achievement has been found to have a pervasive and substantial impact on a wide range of developmental outcomes and has also been implicated in the critical transition from adolescence into early adulthood. Previous research has revealed that self-reported grades tend to diverge from official transcript grade point average (GPA) scores, with students being more likely to report inflated scores. Making use of a sample of monozygotic twin (N = 282 pairs), dizygotic twin (N = 441 pairs), and full sibling (N = 1,757 pairs) pairs from the National Longitudinal Study of Adolescent Health (Add Health; 65 % White; 50 % male; mean age = 16.14), the current study is the first to investigate the role that genetic and environmental factors play in misreporting grade information. A comparison between self-reported GPA (mean score of 2.86) and official transcript GPA scores (mean score of 2.44) revealed that self-reported scores were approximately one-half letter grade greater than official scores. Liability threshold models revealed that additive genetic influences explained between 40 and 63 % of the variance in reporting inflated grades and correctly reporting GPA, with the remaining variance explained by the nonshared environment. Conversely, 100 % of the variance in reporting deflated grade information was explained by nonshared environmental influences. In an effort to identify specific nonshared environmental influences on reporting accuracy, multivariate models that adequately control for genetic influences were estimated and revealed that siblings with lower transcript GPA scores were significantly less likely to correctly report their GPA and significantly more likely to report inflated GPA scores. Additional analyses revealed that verbal IQ and self-control were not significantly associated with self-reported GPA accuracy after controlling for genetic influences. These findings indicate that previous studies that implicate verbal IQ and self-control as significant predictors of misreporting grade information may have been the result of model misspecification and genetic confounding. The findings from the current study indicate that genetic influences play a crucial role in the accuracy in which grade information is reported, but that nonshared environmental influences also play a significant role in specific circumstances. The theoretical and methodological implications of the results are discussed.

Different Slopes for Different Folks: Genetic Influences on Growth in Delinquent Peer Association and Delinquency During Adolescence.

An extensive line of research has identified delinquent peer association as a salient environmental risk factor for delinquency, especially during adolescence. While previous research has found moderate-to-strong associations between exposure to delinquent peers and a variety of delinquent behaviors, comparatively less scholarship has focused on the genetic architecture of this association over the course of adolescence. Using a subsample of kinship pairs (N = 2379; 52% female) from the National Longitudinal Survey of Youth-Child and Young Adult Supplement (CNLSY), the present study examined the extent to which correlated individual differences in starting levels and developmental growth in delinquent peer pressure and self-reported delinquency were explained by additive genetic and environmental influences. Results from a series of biometric growth models revealed that 37% of the variance in correlated growth between delinquent peer pressure and self-reported delinquency was explained by additive genetic effects, while nonshared environmental effects accounted for the remaining 63% of the variance. Implications of these findings for interpreting the nexus between peer effects and adolescent delinquency are discussed.

Exploring whether genetic differences between siblings explain sibling differences in criminal justice outcomes.

Research has revealed that despite many similarities, siblings raised within the same household have also been found to be markedly different from one another. Behavioral differences between siblings have been primarily attributed to differential exposure to a wide variety of environmental influences. The potential role that between-sibling genetic differences play in the development of behavioral differences has been overlooked in the extant literature. The current study examines the association between differences in three dopaminergic polymorphisms (DAT1, DRD2, and DRD4) and differences in arrest, incarceration, and multiple arrests between siblings. Between-sibling difference scores were estimated for each examined polymorphism and each criminal justice outcome measure (along with all controls). Ordinary least squares (OLS) regression models were estimated to examine the potential association between genetic differences between siblings and differences in experiences within the criminal justice system. Models were estimated for the full sample and then for the same-sex male and female subsamples separately. The results provide preliminary evidence that between-sibling differences in some of the examined dopaminergic polymorphisms are associated with differences in contact with the criminal justice system. Findings are discussed in more detail and suggestions for future research are also provided.

The role of gene-gene interaction in the prediction of criminal behavior.

A host of research has examined the possibility that environmental risk factors might condition the influence of genes on various outcomes. Less research, however, has been aimed at exploring the possibility that genetic factors might interact to impact the emergence of human traits. Even fewer studies exist examining the interaction of genes in the prediction of behavioral outcomes. The current study expands this body of research by testing the interaction between genes involved in neural transmission. Our findings suggest that certain dopamine genes interact to increase the odds of criminogenic outcomes in a national sample of Americans.

The 2-repeat allele of the MAOA gene confers an increased risk for shooting and stabbing behaviors.

There has been a great deal of research examining the link between a polymorphism in the promoter region of the MAOA gene and antisocial phenotypes. The results of these studies have consistently revealed that low activity MAOA alleles are related to antisocial behaviors for males who were maltreated as children. Recently, though, some evidence has emerged indicating that a rare allele of the MAOA gene-that is, the 2-repeat allele-may have effects on violence that are independent of the environment. The current study builds on this research and examines the association between the 2-repeat allele and shooting and stabbing behaviors in a sample of males drawn from the National Longitudinal Study of Adolescent Health. Analyses revealed that African-American males who carry the 2-repeat allele are significantly more likely than all other genotypes to engage in shooting and stabbing behaviors and to report having multiple shooting and stabbing victims. The limitations of the study are discussed and suggestions for future research are offered.

Psychopathic personality traits and their influence on parenting quality: results from a nationally representative sample of Americans.

Psychopathic personality traits have consistently been found to predict a range of negative and dysfunctional outcomes. As a result, it is somewhat surprising that the research to date has failed to empirically examine the potential association between psychopathic personality traits and parenting quality. The current study addressed this omission in the literature by analyzing a community sample of adults. The results revealed that respondents scoring higher on psychopathic personality traits tended to report more negative parenting quality. These results were detected for both males and females and remained significant even after controlling for the effects of parental transmission and child-effects. To our knowledge, this is the first study to show a statistically significant association between psychopathic personality traits and parenting quality. We conclude with a discussion of what these findings mean for psychopathy research and the parenting the literature.

Examining the effects of dopamine genes on verbal IQ within and between families.

Although research findings have revealed that both genetic and environmental factors contribute to variation in IQ at the individual level, no studies have examined how genetic differences contribute to differences in IQ within and between families. The current study uses data drawn from the National Longitudinal Study of Adolescent Health (Add Health) to examine the potential role genetic factors play in shaping differences in IQ scores within and between families. The results revealed that while genetic variation between family members did not significantly predict differences in IQ scores, family-level dopaminergic risk scores did significantly predict differences in family-level IQ. The implications of the results are elaborated upon, and suggestions for future research are discussed.