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1.
BMC Health Serv Res ; 22(1): 1029, 2022 Aug 12.
Artigo em Inglês | MEDLINE | ID: mdl-35962358

RESUMO

INTRODUCTION: Regional health care networks with interfaces between clinics, general practitioners and patients can act faster when utilizing digital measures. This manuscript describes the establishment of an online video consultation service in a clinic and its broad health care region to exemplify challenges and solutions for potential future approaches from a management perspective. METHOD: The underlying pilot project was planned and implemented for follow-up monitoring and consultative presentation of orthopedic and trauma patients within the Bundeswehr Medical Service from 2018 to 2020. With predominantly positive evaluation results regarding quality and acceptance among users, this research investigated organizational and processual aspects including total quality management, strategic control and change management approaches. RESULTS: The affected main and subprocesses of patient treatment could be streamlined by the project, as physician recommendations and arrangements could be accelerated and patient travel could be significantly reduced. A SWOT and portfolio analysis showed a high potential for improving existing patient treatment processes for health care enterprises via the use of digital technology. The involved staff should be strategically included at an early stage and continuously involved. By means of a PDCA cycle, the processes of the given project could be exemplarily illustrated with an outlook in the future. DISCUSSION: It has proven successful to consciously use management approaches to establish telemedical integrated care structures in a health region. Recommendations for the strategic introduction of an online video consultation for regional network strengthening and care development for a patient-oriented increase in efficiency could be compiled.


Assuntos
Ortopedia , Telemedicina , Estudos de Viabilidade , Humanos , Projetos Piloto , Encaminhamento e Consulta , Telemedicina/métodos
2.
Unfallchirurg ; 117(8): 710-5, 2014 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-23652929

RESUMO

The peroneal reaction time (PRT) is used in the assessment of neuromuscular deficits in chronic functional ankle instability. Powered by the Editorial Manager and Preprint Manager from Aries Systems Corporation the present study was conducted to determine the PRT in a large collective of patients with chronic ankle instability because it is unclear if this parameter of neuromuscular deficit is prolonged. In this study 186 patients underwent a diagnostic algorithm consisting of anamnesis, clinical examination, X-ray and determination of the PRT on a tilting platform. A prolonged PRT as a manifestation of a neuromuscular deficit could be detected in the majority of the patients (n = 143, 77%). Comparing the affected and healthy legs 77 patients (41%) showed a significant difference in talar shift (p = 0.002) and talar tilt (p = 0.04) in the radiological stress views. Of these 77 patients only 15 (8%) showed radiological evidence of a mechanical problem. As a consequence of recurring ankle sprains a post-traumatic deficit in proprioception has to be expected in most cases. In general a conservative therapy approach should be followed including specific training to improve neuromuscular and proprioceptive deficits.


Assuntos
Articulação do Tornozelo/fisiopatologia , Técnicas de Diagnóstico Neurológico , Instabilidade Articular/diagnóstico , Instabilidade Articular/fisiopatologia , Doenças Neuromusculares/diagnóstico , Doenças Neuromusculares/fisiopatologia , Adulto , Feminino , Alemanha , Humanos , Instabilidade Articular/complicações , Masculino , Pessoa de Meia-Idade , Doenças Neuromusculares/complicações , Exame Físico/métodos , Tempo de Reação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
3.
Zentralbl Chir ; 136(6): 592-7, 2011 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-21563053

RESUMO

BACKGROUND: Abdominal vacuum therapy has simplified the treatment of a laparostoma. But is that all that it can achieve? The role of abdominal vacuum therapy concerning the development of small bowel fistulas is still under discussion. Treatment of the bowel surface seems to be crucial for the prevention of fistulas. As military surgeons, we need a simple, standardised regimen, leading to reproducible good results and low complication rates. The question is: are we able to eliminate small bowel fistula during open abdominal treatment? PATIENTS AND METHODS: We analysed 28  consecutive patients with open abdominal treatment in the period of 2004 to 2009. From June 2006 on, we implemented an algorithm, using the KCI V.A.C.® Abdominal Dressing (Kinetic Concepts Inc., San Antonio, Texas, USA) and a vicryl mesh between the non-adherent layer and the foam to prevent fascial retraction. The patients treated -after the installation of the new algorithm were compared to a group treated from 2004 to May 2006 before its installation. Fistula rates, mortality, the fascial closure rate, the number of abdominal dressing changes and the duration of open -abdominal treatment were evaluated. RESULTS: After implementation of our new algorithm, the fistula rate decreased from 45 % to 0 %. The mortality during open abdominal treatment decreased from 45 % to 6 %. In addition, the duration of open abdominal treatment was reduced as well as the number of dressing changes. The primary fascial closure rate was 87 %. CONCLUSION: We implemented a regimen, which is suitable for our mission in Afghanistan, as well as for medical evacuation and for the treatment of patients in our hospitals in Germany. It ensures a standardised treatment of the open abdominal cavity with an ideal protecting treatment of the bowel surface. Our algorithm utilises the advantages of the laparostoma while minimising the complications. The development of a small bowel fistula was eliminated in the evaluated patient group and mortality was clearly reduced.


Assuntos
Traumatismos Abdominais/cirurgia , Técnicas de Fechamento de Ferimentos Abdominais , Doença Diverticular do Colo/cirurgia , Íleus/cirurgia , Fístula Intestinal/cirurgia , Neoplasias Intestinais/cirurgia , Intestino Delgado/cirurgia , Militares , Tratamento de Ferimentos com Pressão Negativa/métodos , Complicações Pós-Operatórias/cirurgia , Traumatismos Abdominais/mortalidade , Adulto , Afeganistão , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Bandagens , Doença Diverticular do Colo/mortalidade , Fasciotomia , Feminino , Alemanha , Hérnia Abdominal/mortalidade , Hérnia Abdominal/cirurgia , Humanos , Íleus/mortalidade , Fístula Intestinal/mortalidade , Neoplasias Intestinais/mortalidade , Masculino , Pessoa de Meia-Idade , Poliglactina 910 , Complicações Pós-Operatórias/mortalidade , Estudos Retrospectivos , Telas Cirúrgicas , Taxa de Sobrevida , Adulto Jovem
4.
Surg Endosc ; 22(3): 731-8, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17623239

RESUMO

BACKGROUND: Reliable laparoscopic fixation of meshes prior to their fibrous incorporation is intended to minimize recurrences following transabdominal preperitoneal hernia repair (TAPP) and totally extraperitoneal repair (TEP) repair of inguinal hernias. However, suture-, tack- and staple-based fixation systems are associated with postoperative chronic inguinal pain. Initial fixation with fibrin sealant offers an atraumatic alternative, but there is little data demonstrating directly whether fibrin-based mesh adhesion provides adequate biomechanical stability for repair of inguinal hernia by TAPP and TEP. METHODS: Using a newly developed, standardized simulation model for abdominal wall hernias, sublay repairs were performed with six different types of commercially available hernia mesh. The biomechanical stability achieved, and the protection afforded by the mesh-hernia overlap, were compared for three different techniques: nonfixation, point-by-point suture fixation, and fibrin sealant fixation. RESULTS: Mesh dislocation from the repaired hernia defect was consistently seen with nonfixation. This was reliably prevented with all six mesh types when fixed using either sutures or fibrin sealant. The highest stress resistance across the whole abdominal wall was found following superficial fixation with fibrin sealant across the mesh types. There was a highly statistically significant improvement in fixation stability with fibrin sealant versus fixation using eight single sutures (p = 0.008), as assessed by the range of achievable peak pressure stress up to 200 mmHg. CONCLUSIONS: To ensure long-term freedom from recurrence, intraoperative mesh-hernia overlap must be retained. This can be achieved with fibrin sealant up to the incorporation of the mesh - without trauma and with biomechanical stability.


Assuntos
Fenômenos Biomecânicos , Adesivo Tecidual de Fibrina/uso terapêutico , Hérnia Inguinal/cirurgia , Laparoscopia/métodos , Laparotomia/métodos , Telas Cirúrgicas , Cicatrização/fisiologia , Análise de Variância , Humanos , Laparoscopia/efeitos adversos , Laparotomia/efeitos adversos , Modelos Anatômicos , Cavidade Peritoneal , Probabilidade , Sensibilidade e Especificidade , Técnicas de Sutura , Resistência à Tração
5.
Scand J Surg ; 96(4): 263-71, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18265852

RESUMO

Over the last 15 years, the contemporary strategies to treat the open abdomen have reduced the lethal complications. Systematic intensive care and modern wound management in conjunction with a plastic barrier to protect the viscera and topical negative pressure on the soft tissues have reduced the development of small bowel fistulas. The literature selected for this review shows that the surgical handling of the exposed bowel, the choice of the material for temporary coverage and early progressive closure of the defect are crucial for the prevention of fistulas. At present, surgeons worldwide have adopted these principles leading to an increase of primary or delayed closure rates. When a small fistula occurs, biological dressings like human acellular dermal matrix and fibrin glue may help to seal the orifice and to treat the patient conservatively. In case of a large fistula, vacuum-assisted wound management is recommended as well. Through a separate hole in the vacuum sponge matching to the fistula, the enteric contents are sucked off while the wound bed heals and is prepared for split thickness skin graft. Surgical resection of established fistula unresponsive to conservative measures should only be performed on patients well-nourished and free of infection with a delay of at least six months. For patients with an open abdomen, surgical expertise and a well-structured management plan offer the best chances to overcome this potentially devastating condition--with or without fistula.


Assuntos
Traumatismos Abdominais/cirurgia , Fístula Intestinal/prevenção & controle , Laparotomia/métodos , Técnicas de Sutura/instrumentação , Ferimentos Penetrantes/cirurgia , Traumatismos Abdominais/complicações , Humanos , Fístula Intestinal/etiologia , Intestino Delgado , Tampões de Gaze Cirúrgicos , Resultado do Tratamento , Ferimentos Penetrantes/complicações
6.
Hernia ; 10(3): 272-7, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16554980

RESUMO

Endoscopic hernia repair methods have become increasingly popular over the past 15 years. The postulated main advantages of the endoscopic technique are less postoperative pain, early recovery and lower recurrence rates. Fixation of the endoscopic mesh seems to be necessary to minimize the risk of recurrence. Stapling has been implicated to cause chronic inguinal pain syndromes. We performed a retrospective study on male patients who were endoscopically operated on primary inguinal hernias. Our aim was to clarify whether mesh fixation using a fibrin sealant is as safe and reliable as conventional stapling. Additionally, we compared the prevalence of chronic inguinal pain. A standardized population of 133 male patients (mean age 55.9 years) with 186 (80 unilateral; 53 bilateral) consecutive primary laparoscopic total extraperitoneal inguinal hernia repairs was assigned to two groups, depending on whether stapling or a fibrin sealant had been used for mesh fixation. A retrospective case control study was performed to conduct statistical analysis based on the following parameters: recurrence, complications, chronic inguinal pain, foreign body sensation and numbness. Hernia repairs numbering 173 (staples n=87; fibrin n=86) were followed up for a mean duration of 23.7 (11-47) months. The prevalence of chronic inguinal pain was significantly (P=0.002; Fisher exact test) higher in the stapled group-20.7% than in the fibrin sealant group with a prevalence of 4.7%. In terms of recurrence rate, complications and foreign body sensation, fewer patients were affected in the fibrin group than in the reference population, although the differences were not statistically significant. There were no major complications in either of the groups. The mean postoperative stay in hospital was 1.4 days. Fibrin sealing is as effective as stapling in providing secure mesh fixation. The fibrin group displayed a statistically significant lower prevalence of chronic pain syndromes. Mesh sealing provides adequate fixation and reduces the risk of chronic inguinal pain as a complication of the intervention.


Assuntos
Adesivo Tecidual de Fibrina/uso terapêutico , Hérnia Inguinal/cirurgia , Laparoscopia , Dor Pós-Operatória/prevenção & controle , Telas Cirúrgicas , Estudos de Casos e Controles , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Complicações Pós-Operatórias , Recidiva , Estudos Retrospectivos , Estatísticas não Paramétricas , Telas Cirúrgicas/efeitos adversos , Suturas/efeitos adversos , Resultado do Tratamento
7.
Chirurg ; 77(11): 1007-13, 2006 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-17031455

RESUMO

With increasing experience in minimally invasive surgery, laparoscopy's role in abdominal trauma can be defined exactly. Main exclusion criteria are hemodynamic instability and increased intracranial pressure. A literature review of 1996 to 2006 reveals perforating injury mainly of the left thoracoadominal area as the most important indication for laparoscopy . Its goal is to determine intraperitoneal lesions and integrity of the abdominal wall and diaphragm. Minor injuries of the parenchymatous organs and diaphragm can be successfully repaired laparoscopically. In blunt abdominal trauma, laparoscopy is used as a complementary diagnostic device in case ultrasound and multislice CT show unclear findings and the patient's clinical status requires invasive measures. The clear weakness of laparoscopy in abdominal trauma is its inability to identify reliably hollow viscus perforation and retroperitoneal injury. In this, sensitivity is only 25%. In case of proven lesions of the gastrointestinal tract, conversion to laparotomy is to be considered. Despite the reports on laparoscopic treatment, open repair of hollow organ injuries is still to be recommended.


Assuntos
Traumatismos Abdominais/diagnóstico , Laparoscopia , Ferimentos não Penetrantes/diagnóstico , Ferimentos Penetrantes/diagnóstico , Traumatismos Abdominais/cirurgia , Algoritmos , Contraindicações , Análise Custo-Benefício , Humanos , Intestinos/lesões , Intestinos/cirurgia , Laparoscopia/efeitos adversos , Laparoscopia/economia , Fatores de Risco , Sensibilidade e Especificidade , Ferimentos não Penetrantes/cirurgia , Ferimentos Penetrantes/cirurgia
8.
Chirurg ; 77(6): 523-30, 2006 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-16514540

RESUMO

INTRODUCTION: Since the use of prosthetic mesh for the surgical repair of inguinal hernias has become increasingly popular, mesh material introduced during a previous operation is being detected in a growing number of patients undergoing surgery for recurrent hernia. This applies to at least 10% of recurrences. Needed is a therapeutic algorithm for the surgical management of recurrent hernias after previous mesh repair. MATERIAL AND METHODS: A total of 672 recurrent hernia repairs performed in hospitals in the German cities Aachen and Koblenz were analysed in order to review clinical practice. In 92 patients (13.7%) who underwent surgery for recurrent hernia, mesh had been used in the previous hernia repairs. Attention was focused on the location of the recurrence in relation to the site of mesh implantation and on the advantages and disadvantages of the various surgical procedures for repairing recurrent hernias. Re-examination was performed with a mean follow-up of 3 years. RESULTS: Surgeons mostly decided during operation which procedure to use. A transinguinal approach was preferred for patients presenting with recurrent hernia and pain, and mesh material introduced during a previous operation was then explanted. In the case of multiple recurrences, a minimal direct suture repair was used for small defects or a preperitoneal approach for inserting a new, large mesh. The majority of recurrences were medial or suprapubic, especially those occurring after a Lichtenstein repair. After re-examining 87 of 92 patients, nine recurrences (10.3%) were found. Mesh-free suturing methods were affected most frequently. Moderate complaints were reported by 39.1%, and 4.6% suffered from medical chronic pain. CONCLUSION: The surgical management of recurrent hernias after previous mesh repair is a particular challenge for surgeons. We introduce a therapeutic algorithm for recurrent hernia surgery after previous mesh implantation based on analysis of clinical practice.


Assuntos
Hérnia Inguinal/cirurgia , Telas Cirúrgicas , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Recidiva , Reoperação , Fatores de Tempo
9.
Nuklearmedizin ; 44(5): 185-91, 2005.
Artigo em Alemão | MEDLINE | ID: mdl-16395493

RESUMO

AIM: For the surgical therapy of differentiated thyroid cancer precise guidelines are applied by the German medical societies. In a retrospective multicenter study, we investigated the following issues: Are the current guidelines respected? Is there a difference concerning the surgical radicalism and the outcome? Does the perioperative morbidity increase with the higher radicalism of the procedure? PATIENTS, METHODS: Data gained from 102 patients from 17 regional referral hospitals who underwent surgery for thyroid cancer and a following rodioiodine treatment (mean follow up: 42.7 [24-79] months) were analyzed. At least 71 criterias were analyzed in a SPSS file. RESULTS: 46.1% of carcinomas were incidentally detected during goiter surgery. The thyroid cancer (papillary n = 78; follicular n = 24) occurred in 87% unilateral and in 13% bilateral. Papillary carcinomas < 1 cm were detected in 25 cases; in five of these cases (20%) contralateral carcinomas < 1 cm were found. There were significant differences concerning the surgical radicalism: a range from hemithyroidectomy to radical thyroidectomy with lateral neck dissection. Analysis of the histopathologic reports revealed that lymph node dissection was not performed according to guidelines in 55% of all patients. The perioperative morbidity was lower in departments with a high case load. The postoperative dysfunction of the recurrent laryngeal nerve (mean: 7.9% total / 4.9% nerves at risk) variated highly, depending on differences in radicalism and hospitals. Up to now these variations in surgical treatment have shown no differences in their outcome and survival rates, when followed by radioiodine therapy. CONCLUSION: Current surgical regimes did not follow the guidelines in more than 50% of all cases. This low acceptance has to be discussed. The actual discussion about principles of treatment regarding, the so-called papillary microcarcinomas (old term) has to be respected within the current guidelines.


Assuntos
Neoplasias da Glândula Tireoide/cirurgia , Tireoidectomia/normas , Carcinoma Papilar/radioterapia , Carcinoma Papilar/cirurgia , Alemanha , Bócio/complicações , Bócio/cirurgia , Humanos , Radioisótopos do Iodo/uso terapêutico , Guias de Prática Clínica como Assunto , Neoplasias da Glândula Tireoide/radioterapia , Resultado do Tratamento
10.
Chirurg ; 76(8): 765-8, 2005 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-15971036

RESUMO

A 30-year-old, 7-months pregnant woman presented with per anum bleeding. Rectoscopy showed the cause to be a polyp the size of a fingertip 9 cm from the anus. Since the bleeding stopped spontaneously and therefore the need for radical intervention, and due to the advanced pregnancy stage, no biopsy was done. About 1 year later, the same patient experienced sharp pains and anal bleeding during defecation. A poorly defined neuroendocrine carcinoma was diagnosed. Seeking a prognosis optimal for the newborn child, the interdisciplinary decision was made for primary surgery with adjuvant chemotherapy. Other options for this malignancy during and after pregnancy are also discussed.


Assuntos
Pólipos Intestinais/diagnóstico , Melena/etiologia , Tumores Neuroendócrinos/diagnóstico , Complicações Neoplásicas na Gravidez/diagnóstico , Complicações na Gravidez/etiologia , Transtornos Puerperais/diagnóstico , Neoplasias Retais/diagnóstico , Adulto , Biópsia , Diagnóstico Diferencial , Progressão da Doença , Feminino , Humanos , Recém-Nascido , Mucosa Intestinal/patologia , Mucosa Intestinal/cirurgia , Pólipos Intestinais/patologia , Pólipos Intestinais/cirurgia , Metástase Linfática , Melena/patologia , Melena/cirurgia , Invasividade Neoplásica , Estadiamento de Neoplasias , Tumores Neuroendócrinos/patologia , Tumores Neuroendócrinos/cirurgia , Gravidez , Complicações na Gravidez/patologia , Complicações na Gravidez/cirurgia , Complicações Neoplásicas na Gravidez/patologia , Complicações Neoplásicas na Gravidez/cirurgia , Transtornos Puerperais/patologia , Transtornos Puerperais/cirurgia , Neoplasias Retais/patologia , Neoplasias Retais/cirurgia , Reto/patologia , Reto/cirurgia
11.
Am J Surg Pathol ; 28(2): 250-6, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15043316

RESUMO

We describe the clinicopathologic findings in a so far unrecognized thymic tumor. The tumor occurred in a 70-year-old woman with respiratory distress but neither myasthenia gravis nor other symptoms. Metastases or another primary tumor were absent. The well-circumscribed neoplasm was located in the thymic region, measured 18 x 12 x 8 cm, and showed a homogeneous, tan-colored, soft cut surface. By histology, the tumor lacked a true capsule and a lobular growth pattern, was almost devoid of stroma, and infiltrated among remnant thymus lobules. The polygonal tumor cells formed solid sheets, trabeculae, or occurred as single cells that resembled hepatocytes. Proliferative activity was low. Portal structures, sinuses, and bile were absent as were areas of conventional thymoma, adenocarcinoma, or germ cell tumor. The tumor expressed cytokeratins 7 and 19, alpha1-antitrypsin, alpha1-antichymotrypsin, and hep-Par-1. Alpha-fetoprotein (AFP), human beta-chorionic gonadotropin (beta-HCG), placental alkaline phosphatase, CD5, CD30, CD31, CD34, CD45, CD68, CD99, S-100, HMB45, desmin, actin, or neuroendocrine markers were not expressed, and intratumorous CD1a+ or TdT+ immature T cells were absent. AFP was repeatedly undetectable in the blood. Mediastinal tumor recurrence was detected 6 months after surgery. Following radiochemotherapy, the patient has remained free of disease for 26 months. We conclude that this tumor is a thymic carcinoma (WHO type C thymoma). A diagnosis of hepatoid yolk sack tumor appears unlikely considering absence of a bona fide germ cell component, lack of AFP expression, and the patient's female gender. Because of its morphologic and immunohistochemical features, we propose the term "hepatoid thymic carcinoma" for this new type of thymic carcinoma.


Assuntos
Timoma/diagnóstico por imagem , Timoma/patologia , Neoplasias do Timo/diagnóstico por imagem , Neoplasias do Timo/patologia , alfa-Fetoproteínas/deficiência , Idoso , Feminino , Humanos , Imuno-Histoquímica , Timoma/metabolismo , Neoplasias do Timo/metabolismo , Tomografia Computadorizada por Raios X
12.
Arch Surg ; 131(10): 1079-82, 1996 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-8857906

RESUMO

OBJECTIVE: To elucidate whether thoracoscopy for surgical therapy of pneumothorax leads to a reduction of inflammatory responses in comparison with standard thoracotomy. DESIGN: A prospective randomized study PATIENTS: Eleven patients (9 men and 2 women; median age, 28 years; range, 21-44 years) were treated by thoracotomy; 10 patients (9 men and 1 woman; median age, 26 years; range, 21-28 years) were managed thoracoscopically. The plasma concentrations of the following were determined: polymorphonuclear granulocyte elastase and C-reactive protein as inflammatory parameters and prostanoids (prostacyclin, thromboxane A2, prostaglandin F2 alpha, prostaglandin M, and prostaglandin E2) as vasoactive parameters. Blood sampling was performed perioperatively and on day 3 after surgery. RESULTS: The thoracoscopy group revealed a shorter hospital stay (5 vs 7 days; P < .05) and a significantly reduced need for intravenous pain medication within 48 hours (1 vs 3 requirements; P < .01) vs the thoracotomy group. The release of inflammatory (C-reactive protein, P < .01) and vasoactive (prostacyclin and thromboxane A2, P < .01) mediators was less during thoracoscopy compared with standard thoracotomy. CONCLUSIONS: The thoracoscopic procedure is less invasive when performing wedge resection of apical blebs. With intracavitary management being equivalent to the conventional technique, the curtailed morbidity after thoracoscopic surgery is considered to be related to the minimal trauma associated with the access to lung tissue and the reduced handling of lung tissue.


Assuntos
Endoscopia , Pneumotórax/cirurgia , Adulto , Feminino , Humanos , Mediadores da Inflamação/sangue , Masculino , Procedimentos Cirúrgicos Minimamente Invasivos , Pneumonectomia , Estudos Prospectivos , Toracoscopia , Toracotomia
13.
Rofo ; 129(4): 481-4, 1978 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-152247

RESUMO

A four-channel scintillation counter for clearance studies has been connected on-line to a computer. A program has been written which allows the computer to calculate the total clearance rate and the relative contribution of each kidney. The results, together with a semi-automated report, are issued as a letter by teletype. The accuracy of the program has been checked by manual evaluation of the clearance curves.


Assuntos
Rim/metabolismo , Computadores , Humanos , Taxa de Depuração Metabólica , Sistemas On-Line , Contagem de Cintilação
14.
Nuklearmedizin ; 43(4): 121-3, 2004 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-15316578

RESUMO

Total (or near total) thyroidectomy (TE) followed by radioiodine ((131)I) ablation (RIA) of residual thyroid tissue is considered to be the ideal treatment for differentiated thyroid carcinoma. However, the actual guideline of the DGN (German Society of Nuclear Medicine) recommends for the so-called papillary micro-carcinoma of the thyroid (PMC) no further therapeutic strategy (no complete TE, no (131)I-ablation of the remaining lobe). PMC has been defined as papillary carcinoma measuring 1 cm (T1) in maximal diameter according to the World Health Organization classification system for thyroid tumours (1988). The new WHO-classification (starting in 2003) defines the T1-tumour measuring 2 cm in maximal diameter. The authors demand a new, modern guideline, following the new WHO classification. This includes, that despite the overall excellent prognosis for patients with PMC, the treatment of patients with T1-tumours of the new WHO-classification (including the "old" PMC) should be no different from the treatment of patients with conventional papillary thyroid carcinoma, i.e. complete surgery (TE and central lymph node dissection) followed by RIA of residual thyroid tissue. The authors argue that it is not appropriate to consider the tumour size as the single most important key factor for therapy and prognosis. Even small tumours may have poor prognostic factors, such as lymph node metastasis, multifocality or molecular characteristics (expression of oncogenes).


Assuntos
Neoplasias da Glândula Tireoide/terapia , Tireoidectomia/normas , Contraindicações , Alemanha , Humanos , Guias de Prática Clínica como Assunto , Neoplasias da Glândula Tireoide/cirurgia
15.
J Bone Joint Surg Br ; 80(1): 162-8, 1998 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-9460975

RESUMO

To study the effect of ligament injuries and surgical repair we investigated the three-dimensional kinematics of the ankle joint complex and the talocrural and the subtalar joints in seven fresh-frozen lower legs before and after sectioning and reconstruction of the ligaments. A foot movement simulator produced controlled torque in one plane of movement while allowing unconstrained movement in the remainder. After testing the intact joint the measurements were repeated after simulation of ligament injuries by cutting the anterior talofibular and calcaneofibular ligaments. The tests were repeated after the Evans, Watson-Jones and Chrisman-Snook tenodeses. The range of movement (ROM) was measured using two goniometer systems which determined the relative movement between the tibia and talus (talocrural ROM) and between the talus and calcaneus (subtalar ROM). Ligament lesions led to increased inversion and internal rotation, predominantly in the talocrural joint. The reconstruction procedures reduced the movement in the ankle joint complex by reducing subtalar movement to a non-physiological level but did not correct the instability of the talocrural joint.


Assuntos
Articulação do Tornozelo/fisiologia , Instabilidade Articular/fisiopatologia , Ligamentos Articulares/lesões , Ligamentos Articulares/cirurgia , Amplitude de Movimento Articular , Idoso , Feminino , Humanos , Masculino , Articulação Talocalcânea/fisiologia
16.
Hernia ; 7(4): 215-7, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12740692

RESUMO

Intercostal pulmonary herniation occurring years after blunt thoracic trauma is a rare phenomenon. We report on the case of a 66-year-old patient who developed a pulmonary herniation 2 years after a seat-belt injury. Thoracotomy was performed, and the thoracic wall defect was closed with approximating periostal absorbable sutures. The postoperative course was uneventful. Different surgical approaches and the use of prosthetic patches are discussed. Periostal fixation of the adjacent ribs with absorbable sutures is usually sufficient for herniation repair. In cases in which prosthetic meshes are needed, the application of PTFE might produce the best results with the least complications.


Assuntos
Hérnia/etiologia , Herniorrafia , Pneumopatias/etiologia , Pneumopatias/cirurgia , Ferimentos não Penetrantes/complicações , Idoso , Humanos , Masculino , Obesidade/complicações , Cintos de Segurança/efeitos adversos
17.
Hernia ; 8(3): 226-32, 2004 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-15042432

RESUMO

Endoscopic techniques are commonly used for many different types of surgery. It is claimed that videoendoscopic procedures have the advantage of being less traumatic and of offering higher postoperative patient comfort than conventional open techniques. The extent of tissue trauma can be evaluated on the basis of the inflammatory response observed in the wake of surgery. Available studies that have compared endoscopic and conventional techniques suggest that endoscopic cholecystectomy, laparoscopic colorectal resection, and thoracoscopic pulmonary resection have immunologic advantages over conventional approaches. The objective of this prospective study was to determine whether endoscopic hernia repair techniques are also preferable to conventional procedures and to what extent the anesthetic technique (local or general anesthesia) influences the postoperative inflammatory response. For this purpose, biochemical monitoring of cytokine activity [C-reactive protein (CRP), prostaglandin F1alpha (PGF1alpha), neopterin, interleukin-6 (IL-6)] was done prospectively in 101 patients [totally extraperitoneal approach (TEP) n=32, unilateral n=12, bilateral n=20; Shouldice n=69, local anesthesia (LA) n=23, general anesthesia (GA) n=46] before and until 3 days after surgery. The parameters IL-6 and PGF1alpha suggested that the immune trauma immediately after surgery was significantly higher in the group of patients with endoscopic hernia repair than in the group of patients who received a Shouldice repair. No significant differences were observed after the first postoperative day. A comparison between the TEP group and the patients who received conventional surgery under local anesthesia showed that the TEP approach was also associated with a higher postoperative neopterin level. Within the first 3 days after surgical intervention, bilateral endoscopic hernia repair induced no significantly higher inflammatory response than the surgical treatment of unilateral conditions. The anesthetic procedure that was used in the Shouldice operation had no significant effect on inflammatory response. Unlike other types of endoscopic surgery, the repair of groin hernias using an endoscopic technique cannot be regarded as a minimally invasive procedure that is less traumatic than conventional approaches. Instead, the conventional Shouldice procedure appears to cause the lowest inflammatory response and to be the least traumatic approach to hernia repair, especially when it is performed under local anesthesia.


Assuntos
Hérnia Inguinal/cirurgia , Mediadores da Inflamação/análise , Laparoscopia/métodos , Laparotomia/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Proteína C-Reativa/análise , Feminino , Seguimentos , Hérnia Inguinal/diagnóstico , Humanos , Interleucina-6/análise , Laparoscopia/efeitos adversos , Laparotomia/efeitos adversos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Neopterina/análise , Complicações Pós-Operatórias/diagnóstico , Probabilidade , Estudos Prospectivos , Prostaglandinas F/análise , Medição de Risco , Sensibilidade e Especificidade , Estatísticas não Paramétricas , Telas Cirúrgicas , Resultado do Tratamento
18.
Foot Ankle Int ; 18(12): 765-71, 1997 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9429877

RESUMO

The Evans tenodesis is an operative treatment for chronic ankle instability with good short-term results. The disadvantage of impaired hind foot kinematics and restricted motion has been described, and only few reports of long-term results can be found. No techniques have been used to assess the outcome objectively. We wanted to determine whether a modified Evans procedure led to a satisfactory clinical and functional outcome. Nineteen patients were available at a 10-year follow-up. The clinical examination included a detailed questionnaire and stress radiographs. Foot function was evaluated with plantar pressure distribution measurements during walking and peroneal reaction time measurements elicited on a rapidly tilting platform (recorded with surface electromyography). High subjective patient satisfaction was contrasted with a high rate of residual instability, pain, and swelling. The radiographs showed an increased number of exostoses. The gait analysis revealed reduced peak pressures under the lateral heel and increased values under the longitudinal arch. The reaction times of the peroneal muscles were shorter on the operated side (significant: peroneus longus). The persistent clinical problems as well as the functional changes indicate that the disturbed ankle joint kinematics permanently alter foot function and may subsequently support the development of arthrosis. Therefore, the Evans procedure should only be applied if anatomical reconstruction of the lateral ankle ligaments is not feasible.


Assuntos
Articulação do Tornozelo/fisiopatologia , Articulação do Tornozelo/cirurgia , Pé/fisiopatologia , Instabilidade Articular/cirurgia , Tendões/cirurgia , Adulto , Artrite/etiologia , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Pressão , Tendões/fisiopatologia , Resultado do Tratamento
19.
Foot Ankle Int ; 15(9): 477-82, 1994 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-7820239

RESUMO

We followed 38 patients with chronic ankle instability treated by a modified Evans procedure. Evaluation at an average of 68 months follow-up included a standard clinical questionnaire and examination, radiological procedures, and gait analysis. Plantar pressure distribution measurements were recorded during walking and were compared with data from a group of normal subjects (N = 100). The subjective patient questionnaire revealed 87% good or excellent results, but residual pain was reported by 40% of the patients. The gait analysis indicated a significant increase in midfoot loading (22%) consistent with an observed restriction of inversion after surgery. However, the plantar pressure changes were not associated with poor clinical outcome. We cannot say whether these increased pressures will be associated with long-term outcome.


Assuntos
Articulação do Tornozelo/cirurgia , Marcha , Instabilidade Articular/cirurgia , Ligamentos Laterais do Tornozelo/cirurgia , Adulto , Articulação do Tornozelo/fisiologia , Seguimentos , Humanos , Ligamentos Laterais do Tornozelo/fisiopatologia , Satisfação do Paciente , Amplitude de Movimento Articular/fisiologia , Resultado do Tratamento
20.
Foot Ankle Int ; 20(10): 636-9, 1999 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-10540994

RESUMO

The present study investigated the effects of two different surgical procedures for the treatment of chronic ankle instability. Ten patients treated with an anatomic reconstruction using a periosteal flap were compared with a second group that received an Evans tenodesis. All patients were evaluated before and after surgery with clinical and radiographic examinations as well as dynamic pedobarography. Patient satisfaction and radiographic and functional results were comparable in both groups and revealed a good restoration of joint stability and gait symmetry. Our results indicate that both methods of ankle ligament reconstruction achieve a comparable clinical and functional outcome within 1 year after surgery.


Assuntos
Articulação do Tornozelo , Instabilidade Articular/cirurgia , Perna (Membro) , Ligamentos Articulares/cirurgia , Retalhos Cirúrgicos , Tendões/cirurgia , Adulto , Doença Crônica , Humanos , Masculino , Periósteo , Resultado do Tratamento
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