RESUMO
OBJECTIVE: Numerous forces shape the practice of pain management: scientific advances, technical advances, societal expectations, public health crises, reimbursement factors, and the parameters of who gets trained and what motivates the trainees. In this observational study, we sought to determine expressed motivations for entering the subspecialty of pain management, and in particular whether applicants were more interested in procedural skills (our hypothesis) or rehabilitative and cognitive practices. METHODS: We analyzed the personal statements of 142 applicants to the University of Minnesota's pain medicine fellowship program. In addition to those themes, the personal statements were scrutinized for other themes such as interest in teaching and research. Comprehensive vs interventional/procedural interests were coded by a group of four research assistants who were trained using practice essays until they achieved high interrater reliability (alpha > 0.8). Two of the researchers coded for additional themes on a two-point scale indicating presence or absence of a particular theme. When they did not agree, a third researcher broke the tie. Theme prevalence was compared by specialty and gender. RESULTS: Residents expressed interest in interventional and comprehensive pain practice without significant differences; however, there were specialty and gender differences in other themes such as teaching, research, and leadership in program development. CONCLUSIONS: If pain specialty training is going to meet the needs of prospective residents, patients, and society, we should do more to attract women and neurology and psychiatry residents. We should include more opportunities for research and the flexibility to educate trainees who may not pursue a procedural practice.
Assuntos
Internato e Residência , Médicos , Feminino , Humanos , Motivação , Dor , Estudos Prospectivos , Reprodutibilidade dos TestesRESUMO
OBJECTIVE: Understanding the actions of opioids now encompasses pronociceptive as well as antinociceptive mechanisms. Opioid-induced hyperalgesia (OIH) refers to increased pain sensitivity due to high-dose or prolonged opioid exposure. It has become more important as patients with pain remain on opioids at higher doses for longer periods of time. One setting that highlights the dilemma of OIH is in the opioid-tolerant patient who is hospitalized for painful medical conditions or procedures and is unable to achieve adequate analgesia despite escalating opioid doses. This patient population often requires agents that act synergistically with opioids through different mechanisms to achieve analgesia. Dexmedetomidine is an alpha-2 adrenergic agonist that has been shown to synergize with opioids. SETTING: Tertiary care hospital. DESIGN: Case series. METHOD: Eleven hospitalized patients with OIH received dexmedetomidine to improve pain control and to lower opioid doses while avoiding opioid withdrawal. RESULTS: A total of 64% (7/11) had substantial reductions in their baseline opioid doses at the time of discharge. CONCLUSIONS: The cases presented provide support for the clinical utility of alpha-2 agonists during opioid dose reduction in patients with OIH as well suggesting that they may contribute to the recovery of normal nociceptive and antinociceptive responses.
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Agonistas de Receptores Adrenérgicos alfa 2/uso terapêutico , Analgésicos não Narcóticos/uso terapêutico , Analgésicos Opioides/efeitos adversos , Dexmedetomidina/uso terapêutico , Hiperalgesia/induzido quimicamente , Hiperalgesia/tratamento farmacológico , Adolescente , Adulto , Algoritmos , Criança , Tolerância a Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto JovemRESUMO
Although widely practiced in China for 2,000 years, acupuncture was introduced in the United States 40 years ago, and it has only gained acceptance by the medical establishment here in recent years. Now, a growing body of evidence supports its efficacy for a number of conditions, and it is being routinely recommended for them. This article provides an overview of acupuncture and reviews some of the evidence showing its effectiveness for treating various conditions.
Assuntos
Terapia por Acupuntura/métodos , Medicina Baseada em Evidências , Humanos , Minnesota , Resultado do TratamentoRESUMO
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, and nondiabetlc neuropathy occurring in patients with diabetes mellitus. Together, these cases bring clarity to the confusing clinical experience for patients who have decreased sensation in combination with burning pain, and they apply the consensus guidelines for DPNP. Recently approved medications by the Food and Drug Administration for the treatment of DPNP offer hope for many patients whose pain was thought to be refractory to treatment.
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Neuropatias Diabéticas/diagnóstico , Neuropatias Diabéticas/tratamento farmacológico , Dor Intratável/etiologia , Idoso , Comorbidade , Neuropatias Diabéticas/complicações , Neuropatias Diabéticas/epidemiologia , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Dor Intratável/diagnóstico , Dor Intratável/tratamento farmacológico , Doença de Parkinson/epidemiologia , Doenças do Sistema Nervoso Periférico/diagnóstico , Polineuropatias/diagnóstico , Guias de Prática Clínica como AssuntoRESUMO
Despite the number of patients affected by diabetic peripheral neuropathic pain (DPNP), little consensus exists about the pathophysiology, best diagnostic tools, and primary treatment choices. Theories about the causes of DPNP are inextricably linked with the causes of diabetic neuropathles, yet most patients with such neuropathies do not experience pain. The factors that differentiate patients with pain from those without remain unknown and are the subject of much research. When choosing treatment for patients with DPNP, physicians are confronted with a myriad of choices, none of which has been shown to be effective for all patients. This article reviews the evidence for these treatments and attempts to guide physicians in choosing those treatments based on evidence from well-designed clinical trials to support their use. Two agents, duloxetine and pregabalin, are formally approved by the Food and Drug Administration for the treatment of DPNP. In addition, several other agents, including the tricyclic class of antidepressants, have been effective in clinical trials. Ultimately, treatment choice must also Include consideration of adverse effects, individual patient factors such as comorbidities, and often cost.
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Neuropatias Diabéticas/tratamento farmacológico , Analgésicos Opioides/uso terapêutico , Anestésicos Locais/uso terapêutico , Anticonvulsivantes/uso terapêutico , Antidepressivos/uso terapêutico , Medicina Baseada em Evidências , Humanos , Guias de Prática Clínica como AssuntoRESUMO
UNLABELLED: The objective of this retrospective study was to test the validity and reliability of a scoring tool (the DIRE Score), for use by clinicians, that predicts which chronic noncancer pain patients will have effective analgesia and be compliant with long-term opioid maintenance treatment. DIRE scores were assigned to 61 cases from the pain center's databases. These cases were abstracted into vignettes that were reviewed and scored by 6 physicians. Repeat scoring was carried out on a subset of 30 vignettes after 2 weeks. The main outcome measures were: global impression of compliance and efficacy as indicated in the medical record and by interview with the patient's treating clinician; and final disposition, ie, whether or not opioids were continued or discontinued at the time of last clinical documentation. Internal consistency of the factors making up the DIRE Score was high (Cronbach's alpha = .80). Sensitivity and specificity of the DIRE Score for predicting patient compliance were 94% and 87%, respectively. For efficacy, sensitivity and specificity were 81% and 76%. For disposition, the sensitivity and specificity were 86% and 73%. Intraclass correlation was 0.94 for interrater reliability and 0.95 for intrarater reliability. PERSPECTIVE: Public controversy about the use of long-term opioids for chronic pain fuels physician ambivalence about the prescribing process. In this initial retrospective study, validity and reliability of the DIRE Score are demonstrated. The score correlated well with measures of patient compliance and efficacy of long-term opioid therapy.
Assuntos
Analgésicos Opioides/uso terapêutico , Avaliação de Resultados em Cuidados de Saúde/métodos , Medição da Dor/métodos , Dor Intratável/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Minnesota , Dor Intratável/diagnóstico , Dor Intratável/psicologia , Cooperação do Paciente/estatística & dados numéricos , Valor Preditivo dos Testes , Reprodutibilidade dos Testes , Estudos Retrospectivos , Resultado do TratamentoRESUMO
BACKGROUND: Manual therapies for chronic neck pain (NP) are imprecise, inconsistent, and brief because of therapist fatigue. OBJECTIVE: Investigate the safety and efficacy of computerized mobilization of the cervical spine in the sagittal plane for the treatment of chronic NP. DESIGN: Pilot open trial. SETTING: : Physical therapy outpatient department. PARTICIPANTS: Ten patients with chronic NP. INTERVENTIONS: A computerized cradle capable of 3-dimensional neck mobilization was utilized. However, in the present trial the cradle was only utilized in the sagittal plane. Treatment sessions lasted 20 minutes, biweekly, for 6 weeks. MAIN OUTCOME MEASURES: : Numerical rating scale for pain, Neck Disability Index questionnaire, muscle algometry, cervical range of motion (CROM), surface electromyography, and 36-item Short Form Health Survey questionnaire. RESULTS: Treatment was not associated with any significant adverse effects. Pain scores reduced by 2 ± 0.5 numerical rating scale points. CROM showed significant improvement at the end of the study (P<0.05). Neck Disability Index showed marked improvement by the fourth week, end of study, and 2 weeks after treatment (P<0.05); headache subscale showed marked reduction. CONCLUSIONS: These preliminary results demonstrate the safety of a novel computerized mobilization of the cervical spine. In addition, the data suggest that this method is effective in increasing CROM and in alleviating NP and associated headache.
Assuntos
Vértebras Cervicais/fisiologia , Dor Crônica , Manipulação da Coluna/métodos , Cervicalgia/reabilitação , Terapia Assistida por Computador/métodos , Adulto , Algoritmos , Dor Crônica/reabilitação , Avaliação da Deficiência , Eletromiografia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Medição da Dor , Limiar da Dor/fisiologia , Projetos Piloto , Pressão/efeitos adversos , Amplitude de Movimento Articular/fisiologia , Inquéritos e Questionários , Resultado do TratamentoRESUMO
OBJECTIVE: To study the factors that influence the use of opioids in the management of chronic noncancer pain (CNCP) by primary care providers (PCPs) for patients returning from a pain specialist. DESIGN: A survey of PCPs. SETTING: Two physician groups in the Minneapolis-St. Paul metropolitan area. PARTICIPANTS: Two seventy-six PCPs surveyed and 80 surveys returned. MAIN OUTCOME MEASURES: Participants rated the importance of specific concerns regarding the role of pain specialists and the use of opioids in the management of CNCP. Past experience with pain specialists, comfort using opioids, and opinions regarding a trilateral opioid agreement were also examined. RESULTS: The top concerns for PCPs were as follows: the use of opioids in patients with chemical dependency or psychological issues, the escalation of opioid dosing, and the use of opioids in pain states without objective findings. They also ranked highly the importance of coordinating the return of patients from a pain specialist with explicit opioid instructions and the availability of consultation by phone or a timely follow-up visit. PCPs were supportive of the concept of a trilateral opioid agreement. CONCLUSIONS: PCPs have significant concerns regarding the prescribing of opioids in CNCP. They desire closer collaboration with pain specialists, including more explicit plans of care when patients are transferred back to them. The trilateral agreement may provide one framework for better collaboration.