Detalhe da pesquisa
1.
Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
PLoS Pathog
; 19(2): e1011124, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854028
2.
Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development.
PLoS Pathog
; 18(3): e1010363, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35333915
3.
A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection.
BMC Biol
; 19(1): 25, 2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33557824
4.
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.
Sci Transl Med
; 14(656): eabn3231, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921477
5.
Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites.
iScience
; 23(12): 101871, 2020 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33336164
6.
Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon.
mBio
; 10(4)2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31266861
7.
High-content imaging assay to evaluate Toxoplasma gondii infection and proliferation: A multiparametric assay to screen new compounds.
PLoS One
; 13(8): e0201678, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157171
8.
Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii.
PLoS One
; 11(7): e0159306, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27458822