Detalhe da pesquisa
1.
Tau depletion in human neurons mitigates Aß-driven toxicity.
Mol Psychiatry
; 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361127
2.
REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model.
J Neurosci
; 41(16): 3731-3746, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33563726
3.
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.
J Neurosci
; 40(39): 7559-7576, 2020 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868457
4.
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Hum Mol Genet
; 28(12): 2001-2013, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753527
5.
Selective vulnerability in α-synucleinopathies.
Acta Neuropathol
; 138(5): 681-704, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006067
6.
Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo.
Mol Ther
; 25(10): 2404-2414, 2017 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927576
7.
Alpha-synuclein oligomers: a new hope.
Acta Neuropathol
; 134(6): 819-838, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28803412
8.
Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-ß-dependent activation of matrix metalloproteases.
Carcinogenesis
; 37(1): 18-29, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26503968
9.
Canonical and noncanonical Wnt signaling in neural stem/progenitor cells.
Cell Mol Life Sci
; 72(21): 4157-72, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26306936
10.
A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells.
Stem Cells
; 32(12): 3196-208, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25100239
11.
Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation.
NPJ Parkinsons Dis
; 10(1): 82, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609392
12.
Histological Examination of Mitochondrial Morphology in a Parkinson's Disease Model.
J Vis Exp
; (196)2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37427919
13.
Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons.
iScience
; 26(7): 107044, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37426342
14.
Distinct expression and activity of GSK-3α and GSK-3ß in prostate cancer.
Int J Cancer
; 131(6): E872-83, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539113
15.
Fate mapping reveals mixed embryonic origin and unique developmental codes of mouse forebrain septal neurons.
Commun Biol
; 5(1): 1137, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302841
16.
Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer's disease.
Acta Neuropathol Commun
; 9(1): 18, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509301
17.
Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol.
Front Cell Neurosci
; 15: 658244, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33935654
18.
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
EMBO Mol Med
; 13(9): e14745, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34309222
19.
GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model.
Nat Commun
; 11(1): 4958, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33009395
20.
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.
Nat Commun
; 11(1): 4885, 2020 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32985503