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Forward Brillouin scattering interactions support the sensing and analysis of media outside the cladding boundaries of standard fibers, where light cannot reach. Quantitative point-sensing based on this principle has yet to be reported. In this work, we report a forward Brillouin scattering point-sensor in a commercially available, off-the-shelf multi-core fiber. Pump light at the inner, on-axis core of the fiber is used to stimulate a guided acoustic mode of the entire fiber cross-section. The acoustic wave, in turn, induces photoelastic perturbations to the reflectivity of a Bragg grating inscribed in an outer, off-axis core of the same fiber. The measurements successfully analyze refractive index perturbations on the tenth decimal point and distinguish between ethanol and water outside the centimeter-long grating. The measured forward Brillouin scattering linewidths agree with predictions. The acquired spectra are unaffected by forward Brillouin scattering outside the grating region. The results add point-analysis to the portfolio of forward Brillouin scattering optical fiber sensors.
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Brillouin-Enhanced Four-Wave-Mixing techniques, which couple four optical beams through Brillouin nonlinearity, have gained popularity in the 1980's largely owing to their phase conjugation properties. Experiments were mainly conducted in liquid cells. The interest in Brillouin-Enhanced Four-Wave-Mixing has reawakened in the 2000's, following the quest for dynamically reconfigurable gratings in optical fibers. Termed Brillouin Dynamic Grating this time around, it is, in fact, an acoustic wave, optically generated by stimulated Brillouin scattering process between two pump waves. The acoustic wave either carries the coherent information encoded by the pump beams, or in the case of sensing applications, its properties are determined by the environmental parameters. This information, in turn, is imparted to the third phase-matched optical probe wave through the elasto-optic effect. Over the last decade, this mechanism allowed for the realization of many all-optical signal processing functions and has proven instrumental in distributed sensing applications. This paper describes the basics, as well as the state of the art, of BDG-based applications in optical fibers. It also surveys the efforts being done to carry over these concepts to the photonic chip level.
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A novel technique combining Brillouin phase-shift measurements with Brillouin dynamic gratings (BDGs) reflectometry in polarization-maintaining fibers is presented here for the first time. While a direct measurement of the optical phase in standard BDG setups is impractical due to non-local phase contributions, their detrimental effect is reduced by ~4 orders of magnitude through the coherent addition of Stokes and anti-Stokes reflections from two counter-propagating BDGs in the fiber. The technique advantageously combines the high-spatial-resolution of BDGs reflectometry with the increased tolerance to optical power fluctuations of phasorial measurements, to enhance the performance of fiber-optic strain sensors. We demonstrate a distributed measurement (20cm spatial-resolution) of both static and dynamic (5kHz of vibrations at a sampling rate of 1MHz) strain fields acting on the fiber, in good agreement with theory and (for the static case) with the results of commercial reflectometers.
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BACKGROUND: Chronic kidney disease (CKD) is a growing public health problem worldwide. The estimated glomerular filtration rate (eGFR) has been advocated as a means to detect CKD. In January 2006, community laboratories in Ontario, Canada, began to report eGFR values along with every serum creatinine result. The present study sought to investigate the impact of eGFR reporting on nephrology referrals and patient outcome. METHODS: We conducted a retrospective analysis of referrals to an adult general nephrology clinic 24 months before and after eGFR reporting took effect. RESULTS: eGFR reporting was associated with a significant rise in the number of referrals (1,330-1,496, p = 0.009), a 33% rise in patient waiting time (from 75 to 100 days, p < 0.001), and an increase in nephrologists' workload. Patients referred after eGFR reporting were older, but suffered from fewer comorbidities such as hypertension and vascular disease. There was an increase in the number of patients referred with stage 3 CKD, but a drop in the proportion of stage 4 and 5 CKD referrals and no change in time to renal replacement therapy. CONCLUSION: Laboratory reporting of eGFR increased nephrology referral volume, patient waiting times, and nephrologists' workload, without a demonstrable benefit in terms of detection and referral of severe (stage 4 and 5) CKD, nor in the reduction of end-stage renal disease frequency.
Assuntos
Taxa de Filtração Glomerular , Encaminhamento e Consulta/estatística & dados numéricos , Insuficiência Renal Crônica/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Distribuição de Qui-Quadrado , Creatinina/sangue , Feminino , Humanos , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Nefrologia/estatística & dados numéricos , Ontário , Insuficiência Renal Crônica/sangue , Insuficiência Renal Crônica/terapia , Terapia de Substituição Renal , Estudos Retrospectivos , Estatísticas não Paramétricas , Fatores de Tempo , Listas de Espera , Carga de TrabalhoRESUMO
The exotic physics emerging in non-Hermitian systems with balanced distributions of gain and loss has recently drawn a great deal of attention. These systems exhibit phase transitions and exceptional point singularities in their spectra, at which eigen-values and eigen-modes coalesce and the overall dimensionality is reduced. So far, these principles have been implemented at the expense of precise fabrication and tuning requirements, involving tailored nano-structured devices with controlled optical gain and loss. In this work, anti-parity-time symmetric phase transitions and exceptional point singularities are demonstrated in a single strand of single-mode telecommunication fibre, using a setup consisting of off-the-shelf components. Two propagating signals are amplified and coupled through stimulated Brillouin scattering, enabling exquisite control over the interaction-governing non-Hermitian parameters. Singular response to small-scale variations and topological features arising around the exceptional point are experimentally demonstrated with large precision, enabling robustly enhanced response to changes in Brillouin frequency shift.
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Opto-mechanical interactions in planar photonic integrated circuits draw great interest in basic research and applications. However, opto-mechanics is practically absent in the most technologically significant photonics platform: silicon on insulator. Previous demonstrations required the under-etching and suspension of silicon structures. Here we present surface acoustic wave-photonic devices in silicon on insulator, up to 8 GHz frequency. Surface waves are launched through absorption of modulated pump light in metallic gratings and thermo-elastic expansion. The surface waves are detected through photo-elastic modulation of an optical probe in standard race-track resonators. Devices do not involve piezo-electric actuation, suspension of waveguides or hybrid material integration. Wavelength conversion of incident microwave signals and acoustic true time delays up to 40 ns are demonstrated on-chip. Lastly, discrete-time microwave-photonic filters with up to six taps and 20 MHz-wide passbands are realized using acoustic delays. The concept is suitable for integrated microwave-photonics signal processing.
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Opto-mechanical oscillators that generate coherent acoustic waves are drawing much interest, in both fundamental research and applications. Narrowband oscillations can be obtained through the introduction of feedback to the acoustic wave. Most previous realizations of this concept, sometimes referred to as "phonon lasers", relied on radiation pressure and moving boundary effects in micro- or nano-structured media. Demonstrations in bulk crystals required cryogenic temperatures. In this work, stimulated emission of highly-coherent acoustic waves is achieved in a commercially-available multi-core fiber, at room temperature. The fiber is connected within an opto-electronic cavity loop. Pump light in one core is driving acoustic waves via electrostriction, whereas an optical probe wave at a different physical core undergoes photo-elastic modulation by the stimulated acoustic waves. Coupling between pump and probe is based entirely on inter-core, opto-mechanical cross-phase modulation: no direct optical feedback is provided. Single-frequency mechanical oscillations at hundreds of MHz frequencies are obtained, with side-mode suppression that is better than 55 dB. A sharp threshold and rapid collapse of the linewidth above threshold are observed. The linewidths of the acoustic oscillations are on the order of 100 Hz, orders of magnitude narrower than those of the pump and probe light sources. The relative Allan's deviation of the frequency is between 0.1-1 ppm. The frequency may be switched among several values by propagating the pump or probe waves in different cores. The results may be used in sensing, metrology and microwave-photonic information processing applications.