Detalhe da pesquisa
1.
Long-term treatment with the mPXR agonist PCN promotes hepatomegaly and lipid accumulation without hepatocyte proliferation in mice.
Acta Pharmacol Sin
; 44(1): 169-177, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773338
2.
Peroxisome proliferator-activated receptor α agonist induces mouse hepatomegaly through the spatial hepatocyte enlargement and proliferation.
Acta Pharmacol Sin
; 44(10): 2037-2047, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37193756
3.
PXR mediates mifepristone-induced hepatomegaly in mice.
Acta Pharmacol Sin
; 43(1): 146-156, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782543
4.
Hepatic Vps33b deficiency aggravates cholic acid-induced cholestatic liver injury in male mice.
Acta Pharmacol Sin
; 43(4): 933-940, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253877
5.
Natural product-based screening led to the discovery of a novel PXR agonist with anti-cholestasis activity.
Acta Pharmacol Sin
; 43(8): 2139-2146, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931017
6.
[Regulation of P-glycoprotein gene expression by PKC/NF-κB-PXR signaling pathway].
Yao Xue Xue Bao
; 52(1): 51-7, 2017 Jan.
Artigo
em Zh
| MEDLINE | ID: mdl-29911380
7.
Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway.
Acta Pharmacol Sin
; 37(3): 382-9, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26806302
8.
[Optimization of midazolam dosage and pharmacokinetics of CYP3A probe substrate in rats].
Yao Xue Xue Bao
; 51(5): 834-8, 2016 05.
Artigo
em Zh
| MEDLINE | ID: mdl-29878735
9.
[Determination of hepatic and small intestinal distribution of lignans of Wuzhi tablet in rats by liquid chromatography tandem mass spectrometry method].
Yao Xue Xue Bao
; 51(12): 1891-6, 2016 12.
Artigo
em Zh
| MEDLINE | ID: mdl-29908561
10.
[Effect of long-term treatment of Wuzhi tablet on the expression and activity of cytochrome P450 3A in rats].
Yao Xue Xue Bao
; 51(9): 1407-11, 2016 09.
Artigo
em Zh
| MEDLINE | ID: mdl-29924520
11.
[Construction and function identification of luciferase reporter gene vectors containing SNPs in NFKBIA gene 3'UTR].
Yao Xue Xue Bao
; 51(1): 80-5, 2016 Jan.
Artigo
em Zh
| MEDLINE | ID: mdl-27405166
12.
Effects of nicotinamide N-methyltransferase on PANC-1 cells proliferation, metastatic potential and survival under metabolic stress.
Cell Physiol Biochem
; 35(2): 710-21, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25592232
13.
N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.
Carcinogenesis
; 35(10): 2264-72, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25115443
14.
In vivo to in vitro effects of six bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) on the CYP3A/P-glycoprotein-mediated absorption and metabolism of tacrolimus.
Drug Metab Dispos
; 42(1): 193-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24195812
15.
Roles of P-glycoprotein and multidrug resistance protein in transporting para-aminosalicylic acid and its N-acetylated metabolite in mice brain.
Acta Pharmacol Sin
; 35(12): 1577-85, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25418377
16.
Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models.
Acta Pharmacol Sin
; 35(2): 283-91, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362330
17.
An updated review of the genus Rhododendron since 2010: Traditional uses, phytochemistry, and pharmacology.
Phytochemistry
; 217: 113899, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37866447
18.
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin A isolated from the herbal medicine Peucedanum praeruptorum.
Planta Med
; 79(16): 1509-15, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24037590
19.
Effect of Wuzhi tablet (Schisandra sphenanthera extract) on the pharmacokinetics of cyclosporin A in rats.
Phytother Res
; 27(8): 1255-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22996305
20.
Genetic polymorphisms of UGT1A8, UGT1A9, UGT2B7 and ABCC2 in Chinese renal transplant recipients and a comparison with other ethnic populations.
Pharmazie
; 68(4): 240-4, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23700788