Detalhe da pesquisa
1.
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
J Antimicrob Chemother
; 79(1): 172-178, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995258
2.
A Quantitative Method for the Study of HIV-1 and Mycobacterium tuberculosis Coinfection.
J Infect Dis
; 227(5): 708-713, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36537213
3.
SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells.
Stem Cells
; 39(10): 1310-1321, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34152044
4.
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Br J Clin Pharmacol
; 87(4): 2078-2088, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085781
5.
The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest.
J Antimicrob Chemother
; 75(2): 362-370, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31665424
6.
Intracellular Pharmacodynamic Modeling Is Predictive of the Clinical Activity of Fluoroquinolones against Tuberculosis.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611354
7.
Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.
Proc Natl Acad Sci U S A
; 113(8): 2080-5, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858419
8.
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.
Bioorg Med Chem
; 26(11): 2996-3005, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779669
9.
Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Proc Natl Acad Sci U S A
; 112(3): 755-60, 2015 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564664
10.
A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials.
J Antimicrob Chemother
; 72(3): 717-726, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27999014
11.
OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens.
Malar J
; 15(1): 344, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27388207
12.
A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.
Angew Chem Int Ed Engl
; 55(22): 6401-5, 2016 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27089538
13.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566611
14.
Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential.
J Antimicrob Chemother
; 69(4): 1005-16, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335485
15.
Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.
J Biol Chem
; 287(13): 9731-9741, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22282497
16.
Antimalarial pharmacology and therapeutics of atovaquone.
J Antimicrob Chemother
; 68(5): 977-85, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292347
17.
Antitubercular pharmacodynamics of phenothiazines.
J Antimicrob Chemother
; 68(4): 869-80, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23228936
18.
Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2.
Nat Commun
; 14(1): 5033, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596260
19.
Age-differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - Effects of vitamin D.
Mucosal Immunol
; 16(6): 776-787, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37574128
20.
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1228: 123823, 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517355