Detalhe da pesquisa
1.
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking.
Proc Natl Acad Sci U S A
; 119(39): e2204396119, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122218
2.
Chronic nSMase inhibition suppresses neuronal exosome spreading and sex-specifically attenuates amyloid pathology in APP knock-in Alzheimer's disease mice.
Neurobiol Dis
; 184: 106213, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37364689
3.
Bile acids and ceramide overcome the entry restriction for GII.3 human norovirus replication in human intestinal enteroids.
Proc Natl Acad Sci U S A
; 117(3): 1700-1710, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896578
4.
Extracellular vesicles in pharmacology: Novel approaches in diagnostics and therapy.
Pharmacol Res
; 175: 105980, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34863822
5.
Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma.
J Allergy Clin Immunol
; 147(5): 1936-1948.e9, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33130063
6.
Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis.
J Lipid Res
; 62: 100021, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33380429
7.
Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis.
J Biol Chem
; 294(2): 502-519, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420430
8.
Role of 1-Deoxysphingolipids in docetaxel neurotoxicity.
J Neurochem
; 154(6): 662-672, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32058598
9.
Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide.
Glia
; 67(3): 498-511, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484906
10.
Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.
Proc Natl Acad Sci U S A
; 113(21): 5928-33, 2016 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27162368
11.
Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes.
J Lipid Res
; 59(3): 488-506, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321137
12.
Increased liver tumor formation in neutral sphingomyelinase-2-deficient mice.
J Lipid Res
; 59(5): 795-804, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29567647
13.
Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.
J Neurosci
; 36(33): 8653-67, 2016 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535912
14.
Promotion of endocytosis efficiency through an ATP-independent mechanism at rat calyx of Held terminals.
J Physiol
; 595(15): 5265-5284, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28555839
15.
Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy.
Angew Chem Int Ed Engl
; 56(22): 6131-6135, 2017 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379629
16.
Lysosphingolipids and sphingolipidoses: Psychosine in Krabbe's disease.
J Neurosci Res
; 94(11): 974-81, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638582
17.
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.
J Biol Chem
; 289(30): 21082-97, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24876379
18.
Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells.
Int J Cancer
; 137(7): 1610-20, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25833198
19.
Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.
BMC Cancer
; 14: 24, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24422988
20.
Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).
J Biol Chem
; 287(25): 21384-95, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532571