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Eur J Clin Microbiol Infect Dis ; 37(9): 1637-1645, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29876774

RESUMO

Despite group A streptococci being an infrequent cause of pharyngitis in adult outpatients, sore throat remains a common indication for antibiotic prescription. This prospective multicentre non-randomised study describes a community pharmacy-based antimicrobial stewardship intervention consisting in the implementation of rapid antigen testing (RAT) for the management of adults with sore throat. Trained pharmacists triaged patients presenting with symptoms of pharyngitis using the modified Centor score. Those at risk for streptococcal infection were tested with RAT. Patients with a positive RAT were invited to consult a physician, whereas others were offered a symptomatic treatment. All patients received educational leaflets and were asked to fill in a follow-up form 7 days later. Ninety-eight pharmacies in one French region participated, and 559 patients were included over 6 months. RAT was proposed in 367 (65.7%) cases, and it was positive in 28 (8.3%). The follow-up form was returned by 140 (38.5%) participants. Of these, 10/10 patients with positive RAT further consulted a physician and were prescribed an antibiotic treatment, whereas 96.5% (110/114) of patients with negative results and not having any other reason to seek for doctor's advice did not consult. All participants found the intervention useful. Pharmacists spent 6-15 min to perform the intervention, and 98.6% (73/74) of pharmacists giving a feedback declared to be ready to implement this intervention in daily practice, if endorsed and reimbursed. Our results suggest that a pharmacy-based programme for the management of sore throat is feasible and could increase adherence to guidelines.


Assuntos
Testes Imunológicos/estatística & dados numéricos , Farmácias/estatística & dados numéricos , Faringite/diagnóstico , Infecções Estreptocócicas/diagnóstico , Streptococcus pyogenes/isolamento & purificação , Antibacterianos/uso terapêutico , Feminino , Seguimentos , França , Fidelidade a Diretrizes , Humanos , Masculino , Farmácias/normas , Farmacêuticos , Faringite/tratamento farmacológico , Estudos Prospectivos , Encaminhamento e Consulta/estatística & dados numéricos , Infecções Estreptocócicas/tratamento farmacológico
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