Detalhe da pesquisa
1.
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Neurobiol Dis
; 132: 104582, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445162
2.
Urine APOL1 Isoforms Reflect Plasma-Derived Liver-Synthesized Proteins.
J Am Soc Nephrol
; 32(10): 2442-2444, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34162735
3.
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.
Alzheimers Dement
; 12(11): 1149-1158, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27224930
4.
Sustained peripheral depletion of amyloid-ß with a novel form of neprilysin does not affect central levels of amyloid-ß.
Brain
; 137(Pt 2): 553-64, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24259408
5.
Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease.
Cardiovasc Res
; 119(7): 1596-1605, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36869765
6.
Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI.
Eur J Neurosci
; 36(9): 3165-72, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22958226
7.
Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [18F]FDG-µPET Study.
J Alzheimers Dis Rep
; 1(1): 169-180, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30480236
8.
Synaptic proteins in CSF relate to Parkinson's disease stage markers.
NPJ Parkinsons Dis
; 3: 7, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28649607
9.
AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics.
J Alzheimers Dis
; 50(4): 1109-23, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26890753
10.
Development of Immunoassays for the Quantitative Assessment of Amyloid-ß in the Presence of Therapeutic Antibody: Application to Pre-Clinical Studies.
J Alzheimers Dis
; 46(4): 1091-101, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402635
11.
Modeling of age-dependent amyloid accumulation and γ-secretase inhibition of soluble and insoluble Aß in a transgenic mouse model of amyloid deposition.
Pharmacol Res Perspect
; 1(2): e00012, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505567
12.
Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease.
J Alzheimers Dis
; 32(4): 939-47, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22936008
13.
Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study.
J Clin Psychiatry
; 70(6): 922-31, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19573486