Detalhe da pesquisa
1.
Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing.
PLoS Biol
; 21(9): e3002308, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37733692
2.
Preclinical studies in Krabbe disease: A model for the investigation of novel combination therapies for lysosomal storage diseases.
Mol Ther
; 31(1): 7-23, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36196048
3.
Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease.
Mol Ther
; 29(5): 1883-1902, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508430
4.
Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis.
Proc Natl Acad Sci U S A
; 116(21): 10488-10493, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068461
5.
Mass spectrometry imaging and LC/MS reveal decreased cerebellar phosphoinositides in Niemann-Pick type C1-null mice.
J Lipid Res
; 61(7): 1004-1013, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371566
6.
The Role of Vesicle Trafficking and Release in Oligodendrocyte Biology.
Neurochem Res
; 45(3): 620-629, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782103
7.
microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease.
Mol Ther
; 26(3): 730-743, 2018 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29433936
8.
Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.
Mol Ther
; 26(3): 874-889, 2018 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29433937
9.
Mechanism of neuromuscular dysfunction in Krabbe disease.
J Neurosci
; 35(4): 1606-16, 2015 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25632136
10.
Fluid levity of the cell: Role of membrane lipid architecture in genetic sphingolipidoses.
J Neurosci Res
; 94(11): 1019-24, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638586
11.
Synaptic failure: The achilles tendon of sphingolipidoses.
J Neurosci Res
; 94(11): 1031-6, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638588
12.
How membrane dysfunction influences neuronal survival pathways in sphingolipid storage disorders.
J Neurosci Res
; 94(11): 1042-8, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638590
13.
Beyond Krabbe's disease: The potential contribution of galactosylceramidase deficiency to neuronal vulnerability in late-onset synucleinopathies.
J Neurosci Res
; 94(11): 1328-32, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638614
14.
A microglial hypothesis of globoid cell leukodystrophy pathology.
J Neurosci Res
; 94(11): 1049-61, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638591
15.
Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency.
J Neurosci Res
; 94(12): 1520-1530, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27426866
16.
Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles.
J Neurosci Res
; 94(11): 1333-40, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638615
17.
Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplant.
J Neurosci Res
; 94(11): 1138-51, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638599
18.
Hematopoietic Stem cell transplantation and lentiviral vector-based gene therapy for Krabbe's disease: Present convictions and future prospects.
J Neurosci Res
; 94(11): 1152-68, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638600
19.
Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients.
J Neurosci Res
; 94(12): 1579-1587, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27557608
20.
Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease.
Hum Mol Genet
; 22(17): 3397-414, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620143