Detalhe da pesquisa
1.
Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning.
Blood
; 135(4): 287-292, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697803
2.
Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1.
J Biol Chem
; 294(10): 3464-3475, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567735
3.
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.
bioRxiv
; 2023 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398288
4.
Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.
Sci Adv
; 9(45): eadi2364, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939186
5.
Plasmodium falciparum resistance to artemisinin-based combination therapies.
Curr Opin Microbiol
; 69: 102193, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36007459
6.
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance.
Cell Chem Biol
; 29(5): 824-839.e6, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233174
7.
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum.
J Med Chem
; 64(5): 2739-2761, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620219
8.
Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance.
Cell Rep
; 29(9): 2917-2928.e5, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31775055
9.
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.
Nat Commun
; 9(1): 3801, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228310
10.
A thiol probe for measuring unfolded protein load and proteostasis in cells.
Nat Commun
; 8(1): 474, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28883394
11.
Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2.
Sci Signal
; 10(480)2017 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28536301
12.
Structural basis of receptor sulfotyrosine recognition by a CC chemokine: the N-terminal region of CCR3 bound to CCL11/eotaxin-1.
Structure
; 22(11): 1571-81, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450766