Detalhe da pesquisa
1.
Extensive Transduction and Enhanced Spread of a Modified AAV2 Capsid in the Non-human Primate CNS.
Mol Ther
; 26(10): 2418-2430, 2018 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057240
2.
MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates.
Gene Ther
; 25(2): 104-114, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29535375
3.
Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity.
Arch Toxicol
; 92(7): 2353-2367, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29785638
4.
AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction.
Mol Ther
; 22(2): 329-337, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419081
5.
Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain.
Magn Reson Med
; 71(1): 19-25, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24346964
6.
Merits of combination cortical, subcortical, and cerebellar injections for the treatment of Niemann-Pick disease type A.
Mol Ther
; 20(10): 1893-901, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22828503
7.
GDNF gene therapy for alcohol use disorder in male non-human primates.
Nat Med
; 29(8): 2030-2040, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580533
8.
Evaluation of pressure-driven brain infusions in nonhuman primates by intra-operative 7 Tesla MRI.
J Magn Reson Imaging
; 36(6): 1339-46, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22887937
9.
Efficient gene therapy-based method for the delivery of therapeutics to primate cortex.
Proc Natl Acad Sci U S A
; 106(7): 2407-11, 2009 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19193857
10.
Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.
J Neurosci
; 30(28): 9567-77, 2010 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20631185
11.
Image-guided convection-enhanced delivery of GDNF protein into monkey putamen.
Neuroimage
; 54 Suppl 1: S189-95, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080195
12.
Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates.
Neuroimage
; 54 Suppl 1: S196-203, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19761848
13.
Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC.
Mol Ther
; 18(8): 1458-61, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20531394
14.
Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors.
Mol Ther
; 18(8): 1490-5, 2010 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551915
15.
Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain.
Stereotact Funct Neurosurg
; 89(3): 141-51, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21494065
16.
Ultrasound-enhanced drug transport and distribution in the brain.
AAPS PharmSciTech
; 11(3): 1005-17, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20532711
17.
Real-time MR imaging of adeno-associated viral vector delivery to the primate brain.
Neuroimage
; 47 Suppl 2: T27-35, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19095069
18.
Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.
J Neurooncol
; 95(2): 185-197, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19466380
19.
Biodistribution of adeno-associated virus type-2 in nonhuman primates after convection-enhanced delivery to brain.
Mol Ther
; 16(7): 1267-75, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18523450
20.
Infuse-as-you-go convective delivery to enhance coverage of elongated brain targets: technical note.
J Neurosurg
; : 1-8, 2019 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299656