Detalhe da pesquisa
1.
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Br J Cancer
; 122(2): 233-244, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819186
2.
A novel variant of the 13C-methacetin liver function breath test that eliminates the confounding effect of individual differences in systemic CO2 kinetics.
Arch Toxicol
; 94(2): 401-415, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32020249
3.
Physiologically based toxicokinetic models and in silico predicted partition coefficients to estimate tetrachlorodibenzo-p-dioxin transfer from feed into growing pigs.
Arch Toxicol
; 94(1): 187-196, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31728592
4.
A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism.
PLoS Comput Biol
; 14(2): e1006005, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29447152
5.
The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism--insights from mathematical modeling.
BMC Biol
; 14: 15, 2016 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26935066
6.
Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism.
PLoS Comput Biol
; 8(6): e1002577, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22761565
7.
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology.
Mol Syst Biol
; 6: 411, 2010 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20823849
8.
IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities.
Biophys J
; 98(11): 2478-86, 2010 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20513391
9.
Local oxygen homeostasis during various neuronal network activity states in the mouse hippocampus.
J Cereb Blood Flow Metab
; 39(5): 859-873, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29099662
10.
The stability and robustness of metabolic states: identifying stabilizing sites in metabolic networks.
Mol Syst Biol
; 3: 146, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18004279
11.
Corrigendum to "Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species".
Int J Cell Biol
; 2018: 6139262, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30271435
12.
HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology.
Nat Commun
; 9(1): 2386, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29921957
13.
Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.
Oncotarget
; 8(62): 105882-105904, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29285300
14.
Sequential metabolic phases as a means to optimize cellular output in a constant environment.
PLoS One
; 10(3): e0118347, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25786979
15.
Regulation of liver metabolism by the endosomal GTPase Rab5.
Cell Rep
; 11(6): 884-892, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937276
16.
Cytosolic processing of proteasomal cleavage products can enhance the presentation efficiency of MHC-1 epitopes.
Genome Inform
; 15(1): 24-34, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15712107
17.
A method for classifying metabolites in topological pathway analyses based on minimization of pathway number.
Biosystems
; 70(3): 255-70, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12941488
18.
Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis.
FEBS J
; 280(20): 5080-93, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23937586
19.
Assessment of hepatic detoxification activity: proposal of an improved variant of the (13)c-methacetin breath test.
PLoS One
; 8(8): e70780, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23967104
20.
Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species.
Int J Cell Biol
; 2012: 757594, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22719765