Detalhe da pesquisa
1.
Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain.
PLoS Genet
; 19(1): e1010558, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36626371
2.
Tenofovir Douche as HIV Preexposure Prophylaxis for Receptive Anal Intercourse: Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics (DREAM 01).
J Infect Dis
; 229(4): 1131-1140, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38019657
3.
Pharmacogenomics of Antiretroviral Drug Metabolism and Transport.
Annu Rev Pharmacol Toxicol
; 61: 565-585, 2021 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32960701
4.
Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease.
J Biol Chem
; 298(6): 101960, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452678
5.
Biotransformation of Efavirenz and Proteomic Analysis of Cytochrome P450s and UDP-Glucuronosyltransferases in Mouse, Macaque, and Human Brain-Derived In Vitro Systems.
Drug Metab Dispos
; 51(4): 521-531, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36623884
6.
Achieving a Deeper Understanding of Drug Metabolism and Responses Using Single-Cell Technologies.
Drug Metab Dispos
; 51(3): 350-359, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627162
7.
Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism.
J Biol Chem
; 297(5): 101316, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34678314
8.
A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites.
PLoS Pathog
; 16(2): e1008316, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32059044
9.
Human Cyclophilin B Nuclease Activity Revealed via Nucleic Acid-Based Electrochemical Sensors.
Angew Chem Int Ed Engl
; 61(45): e202211292, 2022 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35999181
10.
Naturally Occurring Mutations to Muscle-Type Creatine Kinase Impact Its Canonical and Pharmacological Activities in a Substrate-Dependent Manner In Vitro.
Mol Pharmacol
; 100(6): 588-596, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34561299
11.
Efavirenz and Efavirenz-like Compounds Activate Human, Murine, and Macaque Hepatic IRE1α-XBP1.
Mol Pharmacol
; 95(2): 183-195, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442673
12.
Tenofovir Plasma Concentration from Preexposure Prophylaxis at the Time of Potential HIV Exposure: a Population Pharmacokinetic Modeling and Simulation Study Involving Serodiscordant Couples in East Africa.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182536
13.
Biotransformation and bioactivation reactions - 2018 literature highlights.
Drug Metab Rev
; 51(2): 121-161, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31170851
14.
Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities.
Drug Metab Dispos
; 47(10): 1122-1135, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31266753
15.
MALDI Mass Spectrometry Imaging Reveals Heterogeneous Distribution of Tenofovir and Tenofovir Diphosphate in Colorectal Tissue of Subjects Receiving a Tenofovir-Containing Enema.
J Pharmacol Exp Ther
; 367(1): 40-48, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037813
16.
Utility of Different Adherence Measures for PrEP: Patterns and Incremental Value.
AIDS Behav
; 22(4): 1165-1173, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29090394
17.
Single-Stranded Nucleic Acids Bind to the Tetramer Interface of SAMHD1 and Prevent Formation of the Catalytic Homotetramer.
Biochemistry
; 55(44): 6087-6099, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27775344
18.
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
N Engl J Med
; 367(5): 399-410, 2012 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22784037
19.
Valproic acid is a novel activator of AMP-activated protein kinase and decreases liver mass, hepatic fat accumulation, and serum glucose in obese mice.
Mol Pharmacol
; 85(1): 1-10, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24105977
20.
A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy.
Clin Infect Dis
; 58(6): 883-90, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24336828