Detalhe da pesquisa
1.
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis.
EMBO J
; 41(2): e105531, 2022 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34904718
2.
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging.
EMBO J
; 41(22): e111952, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36314651
3.
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis.
Mol Ther
; 31(7): 2240-2256, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37016577
4.
Proteostasis deregulation as a driver of C9ORF72 pathogenesis.
J Neurochem
; 159(6): 941-957, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34679204
5.
ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?
Curr Top Microbiol Immunol
; 414: 131-157, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28864830
6.
rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia.
Mol Ther
; 25(2): 392-400, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28153090
7.
Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus.
ASN Neuro
; 15: 17590914231157974, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36815213
8.
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome.
Dis Model Mech
; 13(10)2020 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32994318
9.
Interplay Between the Unfolded Protein Response and Immune Function in the Development of Neurodegenerative Diseases.
Front Immunol
; 9: 2541, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30450103
10.
Endoplasmic reticulum proteostasis impairment in aging.
Aging Cell
; 16(4): 615-623, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28436203
11.
ER stress links aging to sporadic ALS.
Aging (Albany NY)
; 11(1): 5-6, 2019 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612121
12.
CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system.
Front Cell Neurosci
; 8: 438, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25620910
13.
Commentary: XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity.
Front Aging Neurosci
; 8: 182, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27534903
14.
Are the mechanisms driving somatosensory reorganization cortical or subcortical?
Front Neuroanat
; 8: 62, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25071467