Detalhe da pesquisa
1.
Domino synthesis of 5-aminoimidazoles from Strecker multicomponent adducts via ytterbium-promoted isocyanide insertion/5-exo-dig cyclization.
Mol Divers
; 27(1): 511-515, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35416620
2.
Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds.
Chem Soc Rev
; 50(2): 766-897, 2021 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33350402
3.
Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi.
J Antimicrob Chemother
; 76(8): 2040-2048, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33855442
4.
Visible-Light Photocatalytic Functionalization of Isocyanides for the Synthesis of Secondary Amides and Ketene Aminals.
J Org Chem
; 85(21): 14077-14086, 2020 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074674
5.
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors.
J Enzyme Inhib Med Chem
; 35(1): 584-597, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31992093
6.
SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells.
Int J Mol Sci
; 21(16)2020 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32784899
7.
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors.
Int J Mol Sci
; 21(19)2020 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987835
8.
Special Issue "Advances in Antiviral Agents against SARS-CoV-2 and Its Variants".
Viruses
; 15(9)2023 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37766311
9.
Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.
Eur J Med Chem
; 253: 115311, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043904
10.
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses.
EMBO Mol Med
; 15(5): e17580, 2023 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36946379
11.
An overview on small molecules acting as broad-spectrum agents for yellow fever infection.
Expert Opin Drug Discov
; 17(7): 755-773, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35638299
12.
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities.
J Med Chem
; 65(4): 2716-2746, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33186044
13.
Photomicellar Catalyzed Synthesis of Amides from Isocyanides: Optimization, Scope, and NMR Studies of Photocatalyst/Surfactant Interactions.
ACS Org Inorg Au
; 2(1): 66-74, 2022 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36855402
14.
Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route.
Eur J Med Chem
; 244: 114853, 2022 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36332546
15.
Natural Compounds Inhibit SARS-CoV-2 nsp13 Unwinding and ATPase Enzyme Activities.
ACS Pharmacol Transl Sci
; 5(4): 226-239, 2022 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35434533
16.
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search.
ChemMedChem
; 16(19): 3044-3059, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34032014
17.
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen.
ACS Pharmacol Transl Sci
; 4(3): 1096-1110, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35287429
18.
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View.
ChemMedChem
; 15(24): 2391-2419, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32961008
19.
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase.
ACS Med Chem Lett
; 11(5): 773-782, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435384
20.
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants.
ACS Infect Dis
; 5(6): 982-1000, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30907573