Reconstructing a disambiguation sequence that forms perceptual memory of multistable displays via reverse correlation method: Bias onset perception but gently.

When multistable displays are presented intermittently with long blank intervals, their onset perception is determined by perceptual memory of multistable displays. We investigated when and how it is formed using a reverse correlation method and bistable kinetic depth effect displays. Each experimental block consisted of interleaved fully ambiguous probe and exogenously disambiguated prime displays. The purpose of the former was to "read out" the perceptual memory, whereas the latter contained purely random disambiguation sequences that were presented at the beginning of the prime display, throughout the entire presentation, or at the beginning and the end of the presentation. For each experiment and condition, we selected a subset of trials with disambiguation sequences that led to a change in perception of either the prime itself (sequences that modified perception) or the following fully ambiguous probe (sequences that modified perceptual memory). We estimated average disambiguation sequences for each participant using additive linear models. We found that an optimal sequence started at the onset with a moderate disambiguation against the previously dominant state (dominant perception for the previous probe) that gradually reduced until the display is fully ambiguous. We also show that the same sequence leads to an altered perception of the prime, indicating that perception and perceptual memory form at the same time. We suggest that perceptual memory is a consequence of an earlier evidence accumulation process and is informative about how the visual system treated ambiguity in the past rather than how it anticipates an uncertain future.

History-dependent changes to distribution of dominance phases in multistable perception.

Multistability - spontaneous switches of perception when viewing a stimulus compatible with several percepts - is often characterized by the distribution of durations of dominance phases. For continuous viewing conditions, these distributions are similar for various multistable displays and share two characteristic features: a Gamma-like distribution shape and dependence of dominance durations on the perceptual history. Both properties depend on a balance between self-adaptation (also conceptualized as a weakening stability prior) and noise. Prior experimental work and simulations that systematically manipulated displays showed that faster self-adaptation leads to a more "normal-like" distribution and, typically, to more regular dominance durations. We used a leaky integrator approach to estimate accumulated differences in self-adaptation between competing representations and used it as a predictor when fitting two parameters of a Gamma distribution independently. We confirmed earlier work showing that larger differences in self-adaptation led to a more "normal-like" distribution suggesting similar mechanisms that rely on the balance between self-adaptation and noise. However, these larger differences led to less regular dominance phases suggesting that longer times required for recovery from adaptation give noise more chances to induce a spontaneous switch. Our results also remind us that individual dominance phases are not "independent and identically distributed."

"Aha"ptics: Enjoying an Aesthetic Aha During Haptic Exploration.

Perceptual insight, like recognizing hidden figures, increases the appreciation of visually perceived objects. We examined this Aesthetic Aha paradigm in the haptic domain. Participants were thinking aloud during haptic exploration of 11 visually nonaccessible panels. They explored them again evaluating them on liking, pleasingness, complexity, and interestingness. Afterwards they rated photographs of the panels on the same variables. Haptic pleasingness was predictable by the strength of insight (Aha!) during free exploration and the material feel. Liking was increased when complexity was high in addition. Pleasingness and interest were negatively related to each other but predicted liking in a combined model. Personality and explorative strategies were considered, for example, strength of insight was increased for ambiguity-tolerant people, and people with high need for closure explored more globally. Evaluations of haptic and visual explorations correlated significantly, and in both modalities, complexity correlated more strongly with interest than with liking. Our study transfers the Aesthetic Aha effect to the haptic domain and reveals slight differences in its hedonic quality with a potentially higher relevance of pleasingness. We suggest that revealing a (meaningful) structure during exploration-visually or haptically-can enhance positive affect and interest hereby benefits from an increased level of complexity.

Switch rates for orthogonally oriented kinetic-depth displays are correlated across observers.

When continuously viewing multistable displays, which are compatible with several comparably likely interpretations, perception perpetually switches between available alternatives. Prior studies typically report the lack of consistent individual switch rates across different displays. However, this comparison is based on an assumption that neural representations of physically identical displays are consistent across observers. Yet, given how different individuals are already at the level of the retina, it is likely that the difference in other relevant factors might mask the correlation. To address this issue, we compared switch rates in two kinetic-depth displays (KDE) that rotated around orthogonal axes (45° counterclockwise vs. 45° clockwise relative to the vertical). This ensured that dynamics of multistable perception was based on highly similar, but different and independent neural representations. We also included a Necker cube (NC) display as a control. We report that switch rates were correlated between two kinetic-depth effect displays, but not between either of the KDE and NC displays. This demonstrates that the usual lack of correlation may not be evidence for the lack of a shared pacesetter mechanism of multistable perception, but reflect other factors, such as differently modulated inputs to competing representations. In addition, we asked participants to speed-up or slow-down perceptual alternations and found that only the former ability was correlated across different displays. This indicates that these two types of volitional control may differ in their use of attentional resources.

Perceptual coupling induces co-rotation and speeds up alternations in adjacent bi-stable structure-from-motion objects.

When two bi-stable structure-from-motion (SFM) spheres are presented simultaneously, they tend to rotate in the same direction. This effect reflects a common state bias that is present for various multistable displays. However, it was also reported that when two spheres are positioned so that they touch each other, they tend to counterrotate instead. The latter effect is interpreted as a frictional interaction, indicating the influence of the embedded physics on our visual perception. Here, we examined the interplay between these two biases in two experiments using a wide range of conditions. Those included two SFM shapes, two types of disambiguation cues, the presence or absence of the disambiguation cues, different layout options, and two samples of observers from two different universities (in sum 26 participants). Contrary to the prior report, we observed a robust common state bias for all conditions, including those that were optimized for frictional and "gear meshing" interactions. We found that stronger coupling of perceptual states is accompanied by more frequent synchronous perceptual reversals of the two objects. However, we found that the simultaneity of the individual switches does not predict the duration of the following dominance phase. Finally, we report that stronger perceptual coupling speeds up perceptual alternations.

The Fluency Amplification Model supports the GANE principle of arousal enhancement.

The GANE (glutamate amplifies noradrenergic effects) model described by Mather et al. offers a neurophysiological basis for the arousal mechanism which is essential for empirical aesthetics and Gestalt processing. More generally, the core principle of perception can be interpreted as a continuous processing of competing arousal states, yielding selective amplification and inhibition of percepts to deduce the meaning of a scene.

Patient-specific polyetheretherketone facial implants in a computer-aided planning workflow.

PURPOSE: In the present study, we report an innovative workflow using polyetheretherketone (PEEK) patient-specific implants for esthetic corrections in the facial region through onlay grafting. The planning includes implant design according to virtual osteotomy and generation of a subtraction volume. The implant design was refined by stepwise changing the implant geometry according to soft tissue simulations. MATERIALS AND METHODS: One patient was scanned using computed tomography. PEEK implants were interactively designed and manufactured using rapid prototyping techniques. Positioning intraoperatively was assisted by computer-aided navigation. Two months after surgery, a 3-dimensional surface model of the patient's face was generated using photogrammetry. Finally, the Hausdorff distance calculation was used to quantify the overall error, encompassing the failures in soft tissue simulation and implantation. RESULTS: The implant positioning process during surgery was satisfactory. The simulated soft tissue surface and the photogrammetry scan of the patient showed a high correspondence, especially where the skin covered the implants. The mean total error (Hausdorff distance) was 0.81 ± 1.00 mm (median 0.48, interquartile range 1.11). The spatial deviation remained less than 0.7 mm for the vast majority of points. CONCLUSIONS: The proposed workflow provides a complete computer-aided design, computer-aided manufacturing, and computer-aided surgery chain for implant design, allowing for soft tissue simulation, fabrication of patient-specific implants, and image-guided surgery to position the implants. Much of the surgical complexity resulting from osteotomies of the zygoma, chin, or mandibular angle might be transferred into the planning phase of patient-specific implants.

Happiness takes you right: the effect of emotional stimuli on line bisection.

Emotion recognition is mediated by a complex network of cortical and subcortical areas, with the two hemispheres likely being differently involved in processing positive and negative emotions. As results on valence-dependent hemispheric specialisation are quite inconsistent, we carried out three experiments with emotional stimuli with a task being sensitive to measure specific hemispheric processing. Participants were required to bisect visual lines that were delimited by emotional face flankers, or to haptically bisect rods while concurrently listening to emotional vocal expressions. We found that prolonged (but not transient) exposition to concurrent happy stimuli significantly shifted the bisection bias to the right compared to both sad and neutral stimuli, indexing a greater involvement of the left hemisphere in processing of positively connoted stimuli. No differences between sad and neutral stimuli were observed across the experiments. In sum, our data provide consistent evidence in favour of a greater involvement of the left hemisphere in processing positive emotions and suggest that (prolonged) exposure to stimuli expressing happiness significantly affects allocation of (spatial) attentional resources, regardless of the sensory (visual/auditory) modality in which the emotion is perceived and space is explored (visual/haptic).

Critical success factors for creating sustainable digital health applications: A systematic review of the German case.

Objective: The Covid-19 pandemic has accelerated the adoption of digital technologies to address social needs, leading to increased investments in digital healthcare applications. Germany implemented a special law called the "Digitales Versorgungsgesetz" (DVG-Digital Supply Act) in 2019, which enables the reimbursement of digital health applications, including digital therapeutics (DTx), through a fast-track process. The Federal Institute for Drugs and Medical Devices (BfArM), the German federal authority responsible for overseeing digital health applications, has implemented legislative adjustments since the law's introduction, which have increased requirements for these applications and potentially led to the removal of some from the directory as well as a slowdown in the addition of new ones. To counteract this trend, this work aimed to identify key success factors for digital health applications (DiGAs). Methods: This research identifies critical success factors through a structured literature review for developing sustainable digital health applications within the European healthcare systems, specifically DiGAs. The study aims to support the ongoing digital transformation in healthcare. Results: The identified success factors that significantly impact the sustainability of DiGAs include patient-centered design, application effectiveness, user-friendliness, and adherence to data protection and information security regulations using standardized approaches. These factors are crucial in preventing the failure of DiGA manufacturers in European countries. Conclusion: By considering and implementing these critical success factors, DiGA manufacturers can enhance their chances of long-term success and contribute to the digital transformation of the healthcare system in Europe.

Predicting instabilities: an embodied perspective on unstable experiences with art and design.

Predictive Processing (PP) provides a theoretical framework that describes perception as a process attempting to increase the predictability of stimulations by updating predictions or exploring new sensations. Moreover, perception and action are assumed to be closely linked within this process. While organisms seem to strive for predictability, we sometimes expose ourselves to objects and situations that challenge sense-making-such conditions often break perceptual habits or offer multiple possible meanings. This paper updates a previous qualification of these experiences of 'Semantic Instability' (SeIns) by following an embodied and situated understanding of perception and cognition. We suggest that art perception essentially differs from problem-solving as in engaging with art, we typically integrate contradictory elements dynamically and without the ultimate goal of resolving the contradictions-on the contrary, SeIns itself can generate aesthetic hedonics and interest. We discuss how current embodied accounts of PP might help understand what motivates such unstable yet insightful and pleasurable nonlinear sense-making processes. This article is part of the theme issue 'Art, aesthetics and predictive processing: theoretical and empirical perspectives'.

Factors contributing to the mental wellbeing of Afghan migrants in Iran during the COVID-19 pandemic.

This study aims to explore the factors contributing mental health of Afghan migrants residing in Iran during the COVID-19 pandemic. With a deep understanding of the unique challenges encountered by migrants, especially during times of crisis, this research delves into the influential factors of experienced anxiety, social cohesion, and stress and their significant contribution to the development of depression among Afghan migrants. The study included a sample of 469 individuals from the Afghan migrant community, aged 15 to 80 years. Data collection took place from December to March 2022 in Iran. The study revealed that anxiety and the burden of the COVID-19 pandemic significantly influenced the occurrence of depression among Afghan migrants. Furthermore, the relationship between these factors and depression was mediated by the experience of stress. Conversely, higher levels of perceived social cohesion in the host country were linked to reduced stress and depression among the migrants. As Afghan migrants in Iran face a heightened risk of developing depression, the importance of social support and integration is underscored by the association between higher levels of perceived social cohesion in the host country and reduced levels of stress and depression. Recognizing the vulnerabilities of this population, it becomes evident that fostering social support networks and promoting integration can play a crucial role in mitigating the negative impact of migration-related stressors and enhancing mental wellbeing among this population.

Processing of featural and configural aspects of faces is lateralized in dorsolateral prefrontal cortex: a TMS study.

Facial recognition relies on distinct and parallel types of processing: featural processing focuses on the individual components of a face (e.g., the shape or the size of the eyes), whereas configural (or "relational") processing considers the spatial interrelationships among the single facial components (e.g., distance of the mouth from the nose). Previous neuroimaging evidence has suggested that featural and configural processes may rely on different brain circuits. By using rTMS, here we show for the first time a double dissociation in dorsolateral prefrontal cortex for different aspects of face processing: in particular, TMS over the left middle frontal gyrus (BA8) selectively disrupted featural processing, whereas TMS over the right inferior frontal gyrus (BA44) selectively interfered with configural processing of faces. By establishing a causal link between activation in left and right prefrontal areas and different modes of face processing, our data extend previous neuroimaging evidence and may have important implications in the study of face-processing deficits, such as those manifested in prosopagnosia and autistic spectrum disorders.

Sleep facilitates long-term face adaptation.

Adaptation is an automatic neural mechanism supporting the optimization of visual processing on the basis of previous experiences. While the short-term effects of adaptation on behaviour and physiology have been studied extensively, perceptual long-term changes associated with adaptation are still poorly understood. Here, we show that the integration of adaptation-dependent long-term shifts in neural function is facilitated by sleep. Perceptual shifts induced by adaptation to a distorted image of a famous person were larger in a group of participants who had slept (experiment 1) or merely napped for 90 min (experiment 2) during the interval between adaptation and test compared with controls who stayed awake. Participants' individual rapid eye movement sleep duration predicted the size of post-sleep behavioural adaptation effects. Our data suggest that sleep prevented decay of adaptation in a way that is qualitatively different from the effects of reduced visual interference known as 'storage'. In the light of the well-established link between sleep and memory consolidation, our findings link the perceptual mechanisms of sensory adaptation--which are usually not considered to play a relevant role in mnemonic processes--with learning and memory, and at the same time reveal a new function of sleep in cognition.

Creating a framework for experimentally testing early visual processing: a response to Nurmoja, et al. (2012) on trait perception from pixelized faces.

Nurmoja, Eamets, Härma, and Bachmann (2012) revealed that strongly pixelated pictures of faces still provide relevant cues for reliably assessing the apparent (i.e., subjectively perceived) traits of the portrayed. The present article responds to the paper by developing the outline of a framework for future research to reveal certain steps in processing complex visual stimuli. This framework combines the approach of degradation of the stimuli with the so-called microgenetic approach of percepts based on presentation time limitations. The proposed combination of a particular kind of stimulus manipulation and a specific experimental procedure allows testing targeted assumptions concerning visual processing, not only in the domain of face perception, but in all domains involving complex visual stimuli, for example, art perception.

Connecting the beholder with the artwork: Thoughts on gaining liveliness by the usage of paraphernalia.

When we attend sculptures in museums, they might fascinate us due to the mastery of the material, the inherent dynamics of body language or due to contrapposto or the sheer size of some of these statues such as Michelangelo's David. What is less convincing, however, is the life-alikeness of the face. Actually, most visitors experience dead faces, dead eyes, and static expressions. By merely adding paraphernalia to a face (e.g., a facemask or sunglasses), such unalive sculptures gain vividness and liveliness. This striking effect is demonstrated by applying a facemask and sunglasses to a sculpture on public display in Bamberg, but it can easily be demonstrated on any available sculpture. This simple method might help connect people with sculptures or artworks, in general, to lower the barrier between the beholder and artwork and increase their interaction.

About the Need for a More Adequate Way to Get an Understanding of the Experiencing of Aesthetic Items.

We live in times when neuroscientific methods have become standard methods that many researchers can easily use. While this offers excellent opportunities to understand brain activities linked with aesthetic processing, we face the problem of using sophisticated techniques without a proper and valid theoretical foundation of aesthetics. A further problem arises from sophisticated methods often demanding strict constraints in presenting and experiencing aesthetic stimuli. However, when experiencing aesthetic items, contextual factors matter, e.g., social and situational affordances are essential in triggering a true and deep "Kunsterlebnis" (Experience of Art). Additionally, in Art, it is often not the artwork as an object that matters but the close relationship with and the processing of the artwork. However, art is only one facet of the whole aesthetic domain, beside, e.g., design, architecture, everyday aesthetics, dance, literature, music, and opera. In the present paper, I propose a dynamic and holistic aesthetic perspective that includes the respective context, situation, cognitive and affective traits and state of the beholder, ongoing processes of understanding, Zeitgeist, and other cultural factors, which can be applied to different aesthetic domains. When ignoring such temporal and dynamic factors, we will not understand the qualia of aesthetic processing. These considerations might help researchers in the field of aesthetics to better understand the experiencing of aesthetic items of all kinds-if we ignore these factors, we are missing the essence of experiencing aesthetic items, especially artworks. We aim to sensitize and inform readers about these ideas to inspire a deeper understanding of experiencing aesthetic items and the advancement of a theoretical framework addressing the experiencing of aesthetics from different domains.

Adapting Ourselves, Instead of the Environment: An Inquiry into Human Enhancement for Function and Beyond.

Technology enables humans not only to adapt their environment to their needs but also to modify themselves. Means of Human Enhancement - embodied technologies to improve the human body's capabilities or to create a new one - are the designated means of adapting ourselves instead of the environment. The debate about these technologies is typically fought on ethical soil. However, alarmist, utopian, and science fiction scenarios distract from the fact that Human Enhancement is a historical and pervasive phenomenon incorporated into many everyday practices. In the vein of disentangling conceptual difficulties, we claim that means of Human Enhancement are either physiologically or psychologically embodied, rendering the merging with the human user their most defining aspect. To fulfill its purpose, an enhancement must pass the test-in-the-world, i.e., assisting with effective engagement with a dynamic world. Even if failing in this regard: Human Enhancement is the fundamental and semi-targeted process of changing the users relationship with the world through the physical or psychological embodiment of a hitherto external object and/or change of one's body. This can potentially change the notion of being human. Drawing on a rich body of theoretical and empirical literature, we aim to provide a nuanced analysis of the transformative nature of this phenomenon in close proximity to human practice. Stakeholders are invited to apply the theory presented here to interrogate their perspective on technology in general and Human Enhancement in particular.

Looking for the Edge of the World: How 3D Immersive Audio Produces a Shift from an Internalised Inner Voice to Unsymbolised Affect-Driven Ways of Thinking and Heightened Sensory Awareness.

In this practice-based case study, we investigate the subjective aesthetic and affective responses to a shift from 2D stereo-based modelling to 3D object-based Dolby Atmos in an audio installation artwork. Dolby Atmos is an infinite object-based audio format released in 2012 but only recently incorporated into more public-facing formats. Our analysis focuses on the artist Sadia Sadia's 30-channel audio installation 'Notes to an Unknown Lover', based on her book of free verse poetry of the same title, which was rebuilt and reformatted in a Dolby Atmos specified studio. We examine what effect altered spatiality with an infinite number of 'placements' has on the psychoacoustic and neuroaesthetic response to the text. The effectiveness of three-dimensional (3D) object-based audio is interrogated against more traditional stereo and two-dimensional (2D) formats regarding the expression and communication of emotion and what effect altered spatiality with an infinite number of placements has on the psychoacoustic and neuroaesthetic response to the text. We provide a unique examination of the consequences of a shift from 2D to wholly encompassing object-based audio in a text-based artist's audio installation work. These findings may also have promising applications for health and well-being issues.

Neither entrepreneurship nor intrapreneurship: a review of how to become an innovative split-off start-up.

Splitting off departments from corporations in order to establish corporate start-ups has become of strategic importance for the performance and innovation of corporations. While the settlement process is widely practiced, there is a lack of knowledge of how entrepreneurship may exist in such split-offs. The main aim of this study was to explore how entrepreneurship in corporate start-ups can exist in order to contribute to corporate performance. Based on a systematic literature review from 2021 to 2023, which resulted in a total of 1,516 scientific, English-language articles in economic journals, a total of 150 articles were analyzed in-depth. Our research shows that it is of crucial importance that corporations position leaders with an appropriate mindset and behavior at all levels as early as starting the split-off process, which is, however, neither entrepreneurship nor intrapreneurship. The niche corporative start-up area shows that entrepreneurship is a continuum and requires a new definition of corporate start-up entrepreneurship (CSE). For corporate start-ups to be successful, we revealed that there needs to be (1) the appropriate legal form, which ensures ownership but also the risk of the leaders, (2) an explorative business rather than exploitation, (3) variable compensation rather than fixed and (4) corporate entrepreneurs rather than employees and managers. Implications of the findings for entrepreneurial leadership theory development and future research are discussed.

When a bank becomes a bank, and a bank is the bank but not the bank: Multistability of homonyms' meaning.

Perceptual multistability is well-known and mostly visually demonstrated: Common examples are Necker's cube or Rubin's face-vase that produce qualitatively different percepts continuously oscillating between the solutions despite physically stable stimuli. We lack knowledge about similar phenomena in other domains, for instance in linguistics, where we are faced with homonyms that create multistability of cognitive semantics, differently assigned meanings of identical words. Our participants listened to repeated presentations of homonyms for which two or even three meanings could be assigned, and they reported the dominant meaning perceived at a certain point in time. Results showed that most participants experienced multistability of meaning for homonyms, with semiperiodic changes in dominant meaning similar to multistabity in perception. These findings suggest that multistability is a general property of the brain's neural architecture that resolves ambiguity irrespective of the level of representation.