Detalhe da pesquisa
1.
Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells.
Blood
; 142(12): 1056-1070, 2023 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339579
2.
Combination of dasatinib and venetoclax in newly diagnosed chronic phase chronic myeloid leukemia.
Cancer
; 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38591430
3.
Loss of expression of both miR-15/16 loci in CML transition to blast crisis.
Proc Natl Acad Sci U S A
; 118(11)2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836616
4.
Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition.
Haematologica
; 107(1): 58-76, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33353284
5.
AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia.
Haematologica
; 107(6): 1311-1322, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34732043
6.
Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia.
J Transl Med
; 19(1): 117, 2021 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33743723
7.
Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model.
Haematologica
; 105(5): 1274-1284, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371419
8.
SMAC mimetics as potential cancer therapeutics in myeloid malignancies.
Br J Haematol
; 185(2): 219-231, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30836448
9.
Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML.
Blood
; 138(17): 1637-1641, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232981
10.
Inhibition of menin, BCL-2, and FLT3 combined with a hypomethylating agent cures NPM1/FLT3-ITD/-TKD mutant acute myeloid leukemia in a patient-derived xenograft model.
Haematologica
; 108(9): 2513-2519, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36727398
11.
Glioblastoma and acute myeloid leukemia: malignancies with striking similarities.
J Neurooncol
; 136(2): 223-231, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29196926
12.
Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Br J Haematol
; 167(3): 376-84, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25079338
13.
Survivin is highly expressed in CD34(+)38(-) leukemic stem/progenitor cells and predicts poor clinical outcomes in AML.
Blood
; 120(1): 173-80, 2012 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22645176
14.
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia.
Leukemia
; 38(4): 729-740, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148395
15.
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.
Blood
; 117(3): 780-7, 2011 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21041716
16.
Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia.
Cells
; 12(8)2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37190037
17.
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
Blood Cancer J
; 13(1): 57, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088806
18.
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.
Nat Commun
; 14(1): 5709, 2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726279
19.
Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia.
Cell Death Dis
; 14(8): 573, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644011
20.
Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Cancer Discov
; 13(7): 1656-1677, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088914