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1.
Eur Arch Psychiatry Clin Neurosci ; 272(6): 1073-1085, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34859297

RESUMO

The hypothesis of the psychosis continuum enables to study the mechanisms of psychosis risk not only in clinical samples but in non-clinical as well. The aim of this longitudinal study was to investigate self-disturbances (SD), a risk factor that has attracted substantial interest over the last two decades, in combination with trauma, cognitive biases and personality, and to test whether SD are associated with subclinical positive symptoms (PS) over a 12-month follow-up period. Our study was conducted in a non-clinical sample of 139 Polish young adults (81 females, age M = 25.32, SD = 4.51) who were selected for frequent experience of subclinical PS. Participants completed self-report questionnaires for the evaluation of SD (IPASE), trauma (CECA.Q), cognitive biases (DACOBS) and personality (TCI), and were interviewed for subclinical PS (CAARMS). SD and subclinical PS were re-assessed 12 months after baseline measurement. The hypothesized model for psychosis risk was tested using path analysis. The change in SD and subclinical PS over the 12-month period was investigated with non-parametric equivalent of dependent sample t-tests. The models with self-transcendence (ST) and harm avoidance (HA) as personality variables were found to be well-fitted and explained 34% of the variance in subclinical PS at follow-up. Moreover, we found a significant reduction of SD and subclinical PS after 12 months. Our study suggests that combining trauma, cognitive biases, SD and personality traits such as ST and HA into one model can enhance our understanding of appearance as well as maintenance of subclinical PS.


Assuntos
Transtornos Psicóticos , Viés , Cognição , Feminino , Humanos , Estudos Longitudinais , Personalidade , Transtornos Psicóticos/complicações , Adulto Jovem
2.
Community Ment Health J ; 58(8): 1495-1504, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-35334020

RESUMO

The aim of this study was to assess satisfaction with care and to identify the predictors of this variable among sociodemographic, clinical and social data in a group of patients suffering from schizophrenia under treatment in community mental health teams. The study included 90 patients with a diagnosis of schizophrenia under the care of community mental health teams. Positive and Negative SyndromeScale, Verona Service Satisfaction Scale, Disability Assessment Schedule, Social Network Index and a loneliness scale (UCLA Loneliness Scale)were used in the study. Prognostic factors for higher satisfaction with care in the multivariate model involved: level of disability (Beta = -0.46, p < 0.001), duration of treatment under a CMHT (Beta = 0.36, p < 0.001), age (Beta = -0.37,p < 0.001), and education (Beta = -0.30, p = 0.002). The model explained 43% of the variance in the dependent variable. 1.Satisfaction with care in a CMHT was high. 2. Higher patient satisfaction could be predicted based on a lower level of disability, longer duration of treatment under a CMHT, lower age and lower education.


Assuntos
Serviços Comunitários de Saúde Mental , Esquizofrenia , Humanos , Esquizofrenia/terapia , Satisfação Pessoal , Saúde Mental , Satisfação do Paciente
3.
J Ment Health ; 31(5): 613-623, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32401072

RESUMO

BACKGROUND: Optimizing psychosocial functioning by reducing the severity of negative symptoms are important outcomes for individuals with schizophrenia. Movement-based interventions could be uniquely capable of addressing the non-verbal nature of negative symptoms. AIMS: To examine the treatment effects of a 10-week group dance/movement therapy program on negative symptoms and psychosocial functioning of individuals diagnosed with schizophrenia. METHODS: A mixed methods intervention design (with explanatory intent) was used in which a randomized controlled trial was followed by semi-structured exit interviews. Participants diagnosed with schizophrenia (N = 31) were randomized to two conditions: treatment as usual (TAU) and dance/movement therapy (DMT). Before and after the program participants reported on negative symptoms and psychosocial functioning outcomes. Fifteen participants completed interviews. RESULTS: Quantitative data showed no improvement nor worsening of clinical status in the DMT group. Qualitative data suggested that participation in DMT had a physical impact, resulted in enhanced interpersonal connectivity, sense of integration, emotional support, and symptom management. CONCLUSIONS: Qualitative but not quantitative findings suggest that DMT has potential to enhance psychosocial functioning and to reduce severity of negative symptoms for schizophrenia.


Assuntos
Dançaterapia , Esquizofrenia , Dançaterapia/métodos , Humanos , Projetos Piloto , Esquizofrenia/terapia
4.
Psychol Med ; 50(1): 116-124, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-30626466

RESUMO

BACKGROUND: Childhood trauma, psychosis risk, cognition, and depression have been identified as important risk markers for suicidal behaviors. However, little is known about the interplay between these distal and proximal markers in influencing the risk of suicide. We aim to investigate the interplay between childhood trauma, cognitive biases, psychotic-like experiences (PLEs) and depression in predicting suicidal behaviors in a non-clinical sample of young adults. METHODS: In total, 3495 young adults were recruited to an online computer-assisted web interview. We used the Prodromal Questionnaire to assess PLEs. Childhood trauma was assessed with the Traumatic Experience Checklist (three items) and Childhood Experience of Care and Abuse Questionnaire (CECA.Q, three items). Cognitive biases were assessed with a short version of the Davos Assessment of Cognitive Biases Scale. Suicidality, psychiatric diagnoses, and substance use were screened with a self-report questionnaire. RESULTS: Childhood trauma, as well as PLEs, was associated with an approximately five-fold increased risk of suicidal thoughts and plans as well as suicide attempts. Participants with depression were six times more likely to endorse suicidal behaviors. Path analysis revealed that PLEs, depression and cognitive biases are significant mediators of the relationship between trauma and suicidal behaviors. The model explained 44.6% of the variance in lifetime suicidality. CONCLUSIONS: Cognitive biases, PLEs, and depression partially mediate the relationship between childhood trauma and suicidal behaviors. The interplay between distal and proximal markers should be recognized and become part of clinical screening and therapeutic strategies for preventing risk of suicidality.


Assuntos
Sobreviventes Adultos de Maus-Tratos Infantis/psicologia , Depressão/psicologia , Transtornos Psicóticos/psicologia , Ideação Suicida , Adolescente , Adulto , Viés , Cognição , Depressão/epidemiologia , Feminino , Humanos , Masculino , Polônia/epidemiologia , Transtornos Psicóticos/epidemiologia , Fatores de Risco , Adulto Jovem
5.
Compr Psychiatry ; 96: 152149, 2020 01.
Artigo em Inglês | MEDLINE | ID: mdl-31786489

RESUMO

Perception of humor seems to be often disturbed in schizophrenia, yet current literature is limited and ambiguous on its relationship to psychopathology. A sample of 40 schizophrenia-diagnosed subjects provided humor comprehension and funniness ratings for 60 cartoons and 60 stories with funny, neutral and absurd punchlines. Disorganization syndrome was found to associate with deficits in humor comprehension and experienced funniness in non-humorous stimuli after controlling for cognitive performance, age, sex and medication. The findings are discussed in relation to previous studies on the topic.


Assuntos
Compreensão , Esquizofrenia , Psicologia do Esquizofrênico , Habilidades Sociais , Senso de Humor e Humor como Assunto/psicologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
6.
Compr Psychiatry ; 56: 133-40, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25308404

RESUMO

AIMS: 1. To assess the changes in quality of life indicators in schizophrenia sufferers at three measurement points: 7, 12 and 20 years after the first hospitalization. 2. To assess changes in the level of functioning and psychopathological state. 3. To assess the relationships between quality of life, the level of functioning and the severity of symptoms. METHOD: A sample group of fifty-two people diagnosed with schizophrenia was investigated using the Lehman's QOLQ, the GAF scale and BPRS. RESULTS: A deterioration was noted in the subjective and objective areas of family life and health, subjectively assessed social relationships and objectively assessed finances. The better functioning sub-group returned better scores for the following objective quality of life indicators: free time, family life, health, social relationships and financial situation. The sub-group in remission obtained better results for general, subjective quality of life and for subjectively assessed health, as well as better scores for objectively assessed free time, social relationships, financial situation and health. An improvement in general, subjective quality of life was seen in the sub-group whose symptoms had grown more severe. CONCLUSIONS: The decline in subjective and objective quality of life in the areas of health and family life, in the subjective evaluation of social relationships and in the objective assessment of financial situation was associated with a deterioration in functioning and an absence of symptom remission. The improvement in general, subjective quality of life in the sub-group with severe symptoms may be evidence of the formation of adaptive mechanisms.


Assuntos
Qualidade de Vida , Psicologia do Esquizofrênico , Adulto , Emprego , Família/psicologia , Feminino , Seguimentos , Nível de Saúde , Hospitalização , Humanos , Masculino , Escalas de Graduação Psiquiátrica , Recuperação de Função Fisiológica , Comportamento Social
7.
Psychiatr Pol ; 48(2): 395-400, 2014.
Artigo em Polonês | MEDLINE | ID: mdl-25016775

RESUMO

The aim of this presentation is to give a profile of the history and work of the Polish-German Mental Health Society (PNTZP). Founded in 1990, the PNTZP's supreme objective is to develop and reinforce partnership between Polish and German psychiatry on a range of levels. The methods it uses to further this aim include bilateral meetings, seminars, and annual symposia. In view of its historical roots, the PNTZP is constantly mindful of the excesses perpetrated on the mentally ill during the National Socialist period, and believes it has an obligation to promote a brand of psychiatry founded on the person, respect for human dignity, and the will and individuality of every man. For this reason, ethics are an essential element of discussion, including discussions with patients and their families. The society advocates the implementation of the National Programme of Mental Health Care and the development of community psychiatry in Poland. It supports the development of various structures for the treatment and assistance of people with mental illness, as well as scientific and academic reflection on the social and cultural implications of psychiatric thought and action. It is committed to facilitating the exchange of experiences between different professional groups, patients, and their families in order to promote mutual inspiration and support in the challenging task of developing psychiatry. A record of these years of meetings may be found in the twenty issues of the periodical Dialog. This example of cooperation across official state borders may be held up as a benchmark for the development of European psychiatry, and the joint work and discussions may offer help and inspiration in day-to-day therapeutic practice. The PNTZP is open to new people and initiatives, and is always looking for people willing to get involved in its work.


Assuntos
Serviços Comunitários de Saúde Mental/organização & administração , Relações Interprofissionais , Transtornos Mentais/diagnóstico , Transtornos Mentais/terapia , Sociedades Médicas/organização & administração , Alemanha , Humanos , Programas Nacionais de Saúde/organização & administração , Polônia , Relações Profissional-Paciente , Psiquiatria/organização & administração , Qualidade da Assistência à Saúde
8.
Brain Sci ; 14(3)2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38539644

RESUMO

The aim of this study was to investigate whether Trail Making Test (TMT) performance is associated with the severity of psychopathological symptoms related to psychosis among young adults with elevated level of psychotic-like experiences (PLEs), and whether this relationship is mediated by cognitive biases and socio-occupational functioning. A total of 187 subjects from a larger population of 6722 young adults participated in this 1-year follow-up study. The inclusion criteria were an elevated level of PLEs (the highest score of the Prodromal Questionnaire) and a lack of schizophrenia diagnosis. Eventually, 134 subjects (71.6%) completed the TMT, as well as the DACOBS scale (cognitive biases), at baseline and were examined twice using the CAARMS (psychopathology) and SOFAS (socio-occupational functioning) scales. In the first (I) and second (II) measurements, the calculated effects indicate indirect-only mediations, which explained 35 and 38% of the variance of the CAARMS. The TMT B execution time was positively associated with the DACOBS scale (ß = 0.19, p = 0.028), which was negatively related to the SOFAS I (ß = -0.37, p < 0.001) and SOFAS II (ß = -0.20, p = 0.016) measurements. A lower score on the SOFAS I predicted a higher score on the CAARMS I (ß = -0.50, p < 0.001), and a lower SOFAS II predicted a higher score on the CAARMS II (ß = -0.61, p < 0.001). Subtle EF dysfunctions may, over time, translate into a greater severity of symptoms related to psychosis in people with elevated PLEs, and this is mediated by a deterioration of their metacognition and socio-occupational functioning.

10.
Psychiatr Pol ; 47(5): 775-86, 2013.
Artigo em Polonês | MEDLINE | ID: mdl-25011226

RESUMO

OBJECTIVES: To monitor the effect of interaction of duration of untreated psychosis (DUP) and expressed emotion (EE) on treatment outcomes in schizophrenia. METHODS: 56 individuals diagnosed with schizophrenia were assessed at 4 time points. The number of relapses, the number and duration of rehospitalizations and the severity of symptoms were assessed at index hospitalization and at 3, 7 and 12-year follow-ups. RESULTS: No correlation was found between DUP and EE measured at index hospitalization. Over the 12-year period the number of rehospitalizations for individuals with short DUP and low EE did not increase, as opposed to those with short DUP and with high EE. In the group with long DUP, the number of rehospitalizations increased irrespectively of EE level. The positive syndrome in the group with short DUP and high EE was less severe than in individuals with long DUP and high EE. Analogous differences appeared in the group with low EE. CONCLUSIONS: 1) No correlation was found between DUP and EE at index hospitalization. 2) Number of rehospitalizations and intensity of positive symptoms proved to be associated over time with the interaction of DUP and EE. 3) Long-time observation and multiple assessments allow to obtain more reliable results.


Assuntos
Emoções Manifestas , Hospitalização/estatística & dados numéricos , Transtornos Psicóticos/terapia , Esquizofrenia/terapia , Adulto , Comorbidade , Progressão da Doença , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde , Prognóstico , Transtornos Psicóticos/epidemiologia , Esquizofrenia/epidemiologia , Psicologia do Esquizofrênico , Resultado do Tratamento , Adulto Jovem
11.
Psychiatr Prax ; 50(S 01): S55-S60, 2023 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-37429284

RESUMO

The use of drama therapy in the treatment of people with schizophrenia in a theatre group has a tradition of almost 40 years in Krakow. The preparation of performances and appearances in front of an audience requires the components known from social skills training. In this work, a brief description of the development of "Psyche" theatre and its place in a community-based comprehensive treatment programme is described, using Shakespeare's "A Midsummer Night's Dream" as an example. The casuistry of a patient, serves as an illustration to reflect on the importance of the role in the play for the subsequent in-depth individual psychotherapy. The authors emphasise the attractiveness of the public performances in a Krakow theatre, which serve as opportunities for encounters with young people. They have enormous educational value in reducing prejudice against mentally ill people.


Assuntos
Amor , Esquizofrenia , Humanos , Adolescente , Esquizofrenia/diagnóstico , Esquizofrenia/terapia , Alemanha , Emoções
12.
Psychiatr Pol ; 57(1): 35-50, 2023 Feb 28.
Artigo em Inglês, Polonês | MEDLINE | ID: mdl-37350714

RESUMO

OBJECTIVES: The purpose of this study was to compare satisfaction with care in patients with schizophrenia in two CMHT models: traditional and pilot program group with concurrent assessment of symptom severity and social functioning. METHODS: Ninety patients with schizophrenia treated in Community Mental Health Teams were included in the study, 60 in the traditional model and 30 in the pilot-program model.A demographic data questionnaire, the Positive and Negative Syndrome Scale (PANSS), the Verona Service Satisfaction Scale (VSSS-54), the Disability Assessment Schedule (WHODAS), the Social Network Index (SNI),and a scale measuring loneliness (UCLA Loneliness Scale) were used. RESULTS: The pilot-program group was characterized by significantly lower age of subjects (p=0.048), less psychiatric medication use (p=0.027), higher total(p<0.001) and positive (p<0.001) symptom severity in PANSS, smaller social network (p=0.003), less role activity in social network (p<0.001), higher level of loneliness (p=0.001) and higher level of disability (p<0.001). The pilot-program group had significantly higher satisfaction with involvement of families in the therapeutic process(p = 0.024). CONCLUSIONS: In the pilot-program group, younger, more severely ill patients with higher severity of symptoms and worse social functioning were included in the treatment with no differences in the number of hospitalizations between the groups. It can be concluded that CMHT in the pilot-program Mental Health Centers (MHCs) protects this group of patients from hospitalization. There was also higher satisfaction with family involvement in the therapeutic process in the pilot-program group. A valuable continuation of the study would be to evaluate the treatment outcomes in all CMHTs operating under the pilot-program MHCs.


Assuntos
Esquizofrenia , Humanos , Esquizofrenia/tratamento farmacológico , Satisfação do Paciente , Resultado do Tratamento , Satisfação Pessoal , Inquéritos e Questionários
13.
Psychiatr Pol ; 57(1): 19-33, 2023 Feb 28.
Artigo em Inglês, Polonês | MEDLINE | ID: mdl-37350713

RESUMO

OBJECTIVES: This study aims to assess the caregivers' burden in schizophrenia amongst patients treated by Community Mental Health Teams (CMHTs) and its relation to patients' demographic, clinical and social characteristics, with emphasis on their satisfaction with care, and to evaluate the correlation of selected characteristics of caregivers with the level of their burden. METHODS: A total of 65 patient-caregiver dyads remaining in home treatment were included. Caregivers were assessed with demographic questionnaires, and the Caregiver Burden Inventory (CBI). The patients were assessed with the Positive and Negative Syndrome Scale (PANSS), the Verona Service Satisfaction Scale (VSSS-54), the Disability Assessment Schedule (WHODAS 2.0), the Social Network Index (SNI) and with the UCLA Loneliness Scale. Data were analysed using multiple linear regression. RESULTS: Increased caregiver burden was associated with: greater symptom severity in patients, lower satisfaction with staff professionalism, and a high level of emotional expressiveness in relationships. The regression model explaining 57% of the variance in the caregivers' emotional burden consisted of four factors: the patient's positive syndrome intensity, patient's remaining in an emotional relationship, gender i.e. higher burden amongst female caregivers of male patients, and smaller social network. CONCLUSIONS: The caregivers' burden severity is related to patients' sociodemographic, clinical and social characteristics and their satisfaction with treatment. The emotional burden of caregivers is impacted by: greater symptom severity, especially the positive syndrome, lower patient satisfaction with staff professionalism, and a high expression of emotions in family relationships. The patient's and caregiver's gender and education level, the patient's degree of disability, them being in a relationship and social support network size are also significant.


Assuntos
Cuidadores , Esquizofrenia , Humanos , Masculino , Feminino , Cuidadores/psicologia , Esquizofrenia/terapia , Efeitos Psicossociais da Doença , Interação Social , Satisfação do Paciente , Satisfação Pessoal
14.
Psychiatr Pol ; 57(2): 325-338, 2023 Apr 30.
Artigo em Inglês, Polonês | MEDLINE | ID: mdl-36371737

RESUMO

OBJECTIVES: Virtual Reality (VR) has been widely used in psychiatry, including psychotic disorders. The main advantage of VR is its high ecological validity and controllability of the virtual environment. Our main goal was to test whether, similarly to computer-generated VR, 360-degree videos are able to elicit a state of social paranoia in prone individuals. METHODS: Sixteen schizophrenia patients and twenty-three healthy individuals were assessed using Leibowitz Social Anxiety Scale and additionally, in the patient group, the Positive and Negative Syndrome Scale (PANSS-6) and Peters Delusional Inventory (PDI) were used. The participants viewed four 360-degree videos with and without social content on a VR headset. Meanwhile, subjects' heart rate was measured continuously. After the exposure, both groups were assessed with Social State Paranoia Scale (SSPS) and asked about momentary anxiety and sense of presence. RESULTS: The schizophrenia patients reported higher momentary anxiety, although the results of SSPS did not differ significantly between groups. In the control group the heart rate decreased between first non-social and social video, whereas in the patient group it did not differ significantly. There was a significant correlation of paranoid ideation experienced on daily basis (PDI) and elicited in VR (SSPS) in the patient group. CONCLUSIONS: In conclusion, paranoid responses can be triggered in patients with schizophrenia by 360-degree videos.


Assuntos
Transtornos Psicóticos , Esquizofrenia , Realidade Virtual , Humanos , Transtornos Paranoides , Projetos Piloto , Esquizofrenia/complicações
15.
Psychiatr Pol ; 46(6): 995-1005, 2012.
Artigo em Polonês | MEDLINE | ID: mdl-23479941

RESUMO

In many countries there is a growing awareness of the significance of mutual help among patients suffering from mental illnesses. Such acts provide benefits in terms of a sense of greater activity, self-dependance, it empowers and restores the feeling of influence over one's own and the other's fate. It is a path facilitating the process of recovery. In the last twenty years, the new role of patients in the humanisation of the treatment process in psychiatry was most fully expressed by the creation of independent non-governmental organisations. Those organisations took mutual aid activities, participation in self-education, in the therapeutic process and recently, in scientific research as their main goals. In Poland, an independent movement of patients has been growing since 2003, firstly as an organisation of people suffering from mental illnesses, named as the "Open the doors" Association in Kraków. The authors, in ajoint voice, describe the history, various activities and the significance of this movement, expressing a conviction that the time has come in Poland to formulate a long-term programme of promoting activities which support the process of empowerment and recovery in psychiatric and social institutions. They share the opinion, that the time for radical changes in Polish psychiatry has come with the implementation of the National Program of Mental Health Care. The time for patients to take over more responsibility and for us all to cooperate.


Assuntos
Redes Comunitárias/organização & administração , Transtornos Mentais/reabilitação , Participação do Paciente/estatística & dados numéricos , Relações Profissional-Paciente , Centros de Reabilitação/organização & administração , Apoio Social , Atitude Frente a Saúde , Promoção da Saúde/organização & administração , Humanos , Polônia , Psiquiatria/organização & administração , Comportamento Social
16.
Psychiatr Pol ; 56(2): 205-216, 2022 Apr 30.
Artigo em Inglês, Polonês | MEDLINE | ID: mdl-35988069

RESUMO

OBJECTIVES: The aim of the presented research is to characterize the operating Mental Health Centers (MHCs) and to provide a preliminary assessment of the implementation process of the pilot program model in the area of psychiatric care in Poland. METHODS: The study uses the Polish version of the German questionnaire, which covers four areas: (1) basic conditionsof the model project/pilot program; (2) characteristicsof the organizational structure of the treatment entity; (3) statistical characteristics of the services provided;(4) specific features of the psychiatric care system in model regions/pilot program Mental Health Centers. RESULTS: Nineteen of the 27 Mental Health Centers completed the survey. The centers have 428 beds in day units and 1,971 beds in inpatient units. Most of the centers (15 of 19) work with subcontractors and all are publicly funded. Eight centers were established by psychiatric hospitals and 11 centers were constituted at psychiatric wards within multi-specialist hospitals. The medical services provided by the centers mainly include psychiatry and psychotherapy. In 2019, the centers provided medical services to a total of 65,614 patients; 8,432 patients received at least three forms of treatment. CONCLUSIONS: The first full year of MHC operation in the pilot program indicates the expected direction of change in psychiatric care - achieving a significant level of implementation of community care standards. The survey needs to be repeated to verify this direction. A limitation of the study was the lack of survey responses from 30% of MHCs. In the future, we should aim for at least 90% of completed surveys.


Assuntos
Serviços Comunitários de Saúde Mental , Transtornos Mentais , Hospitais Psiquiátricos , Humanos , Transtornos Mentais/terapia , Saúde Mental , Projetos Piloto
17.
Psychiatr Pol ; : 1-14, 2022 Nov 17.
Artigo em Inglês, Polonês | MEDLINE | ID: mdl-36720175

RESUMO

OBJECTIVES: Virtual reality (VR) is growing in popularity in treating various psychiatric disorders, including psychotic ones. However, no studies have been published on mindfulness interventions aided by virtual reality in psychotic patients to date. METHODS: 25 patients with schizophrenia or schizoaffective disorder were assessed at three time points with 4-week intervals using the six-item Positive and Negative Syndrome Scale (PANSS-6), Quick Inventory of Depressive Symptomatology (QIDS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS-10), and the Addenbrooke's Cognitive Examination III (ACE-III). Additionally, the intensity of seven emotions was rated using the Visual Analog Scale (VAS) before and after each training session. RESULTS: The subjects achieved a significant reduction in symptom severity after completing mindfulness training. This was reflected by the PANSS-6 total score, as well as by the subscales for negative and positive symptoms. A significant increase in cognitive functioning (ACE-III scores) was also found. No significant changes in these measures were observed when only the standard intervention was used. CONCLUSIONS: Our study indicates good feasibility of the developed mindfulness intervention in VR in schizophrenic patients. The results indicate potential benefits in terms of lessening of the symptoms and improvement in cognition.

18.
J Clin Med ; 11(6)2022 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-35329940

RESUMO

Numerous studies have reported that stressful life experiences increase the risk of psychosis and psychotic-like experiences (PLEs). Common variations of the FKBP5 gene have been reported to impact the risk of psychosis by moderating the effects of environmental exposures. Moreover, anxious and avoidant attachment styles have been shown to increase both the level of perceived stress and the risk for psychosis development. In the present cross-sectional study, we aimed to investigate whether variants of the FKBP5 gene moderate the effects of attachment styles and the level of perceived stress on the development of PLEs. A total of 535 non-clinical undergraduates were genotyped for six FKBP5 single nucleotide polymorphisms (SNPs) (rs3800373, rs9470080, rs4713902, rs737054, rs1360780 and rs9296158). The Psychosis Attachment Measure (PAM), the Perceived Stress Scale-10 (PSS-10) and the Prodromal Questionnaire 16 (PQ-16) were administered to assess attachment styles, the level of perceived stress and PLEs, respectively. Anxious attachment style, lower levels of perceived self-efficacy and higher levels of perceived helplessness were associated with a significantly higher number of PLEs. The main effects of attachment style on the severity of PLEs were significant in models testing for the associations with perceived self-efficacy and three FKBP5 SNPs (rs1360780, rs9296158 and rs9470080). The main effect of rs38003733 on the number of PLEs was observed, with GG homozygotes reporting a significantly higher number of PLEs in comparison to T allele carriers. In individuals with dominant anxious attachment style, there was a significant effect of the interaction between the FKBP5 rs4713902 SNP and self-efficacy on the severity of PLEs. Among rs4713902 TT homozygotes, a low level of perceived self-efficacy was associated with higher severity of PLEs. In subjects with non-dominant anxious attachment, a low level of perceived self-efficacy was associated with a higher number of PLEs, regardless of the genotype. Our results indicate that the FKBP5 gene might moderate the relationship between attachment, perceived stress and PLEs.

19.
Med Sci Monit ; 17(5): CR277-83, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21525810

RESUMO

BACKGROUND: The goal of this prognostic study was to investigate whether the duration of untreated psychosis (DUP) may have a prognostic value with regard to the further course of the illness. MATERIAL/METHODS: Fifty-eight patients (77% of the original study group) diagnosed with DSM III schizophrenia and later re-diagnosed with DSM IV T-R were assessed at 4 time points. Number of relapses, average time of inpatient treatment, number of inpatient readmissions, and severity of psychopathological symptoms were assessed at 1-, 3-, 7- and 12-year follow-ups. DUP information was obtained by clinical interview with patients and their families. The severity of symptoms was assessed using BPRS-SA, UCLA version. RESULTS: Increases in the number of relapses at follow-ups were more prominent in the group with a longer DUP (p<0.001). Decreases in the results of BPRS (symptom improvement) were more prominent in patients with a shorter DUP. The latter had significantly lower results than patients with a long DUP at each assessment except the index hospitalization (p equalled, respectively: 0.449; 0.002; 0.012; 0.034 and 0.014). Decreases in positive symptoms were greater in patients with a short DUP--significant at all except the 7-year follow-up (p equalled respectively: 0.230; <0.001; 0.011; 0.214; <0.001). CONCLUSIONS: 1) A positive correlation was found between DUP and the dynamics of general and positive symptoms and the number of relapses. 2) There was no significant relationship between DUP and the dynamics of negative symptoms, whereas the relationship between the time and number of re-hospitalizations was marginally significant.


Assuntos
Transtornos Psicóticos/diagnóstico , Transtornos Psicóticos/terapia , Esquizofrenia/diagnóstico , Esquizofrenia/terapia , Adulto , Análise de Variância , Demografia , Feminino , Humanos , Masculino , Readmissão do Paciente , Prognóstico , Recidiva , Fatores de Tempo , Resultado do Tratamento
20.
Soc Psychiatry Psychiatr Epidemiol ; 46(7): 643-50, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20495975

RESUMO

BACKGROUND: In recent years, there has been a growing awareness of the stigma experienced by people with mental illnesses and their families. The aim of this study is to assess the amount of stigma anticipated and experienced by schizophrenia patients in one region of Poland and to examine how these figures relate to socio-demographic and clinical correlates. METHOD: Subjective stigmatisation was assessed using the Inventory of Stigma Experiences of Psychiatric Patients. The mental health centres in Malopolska selected for the study were facilities representative of the whole region as regards location and type of treatment. Out of 250 patients contacted, 202 participated in the study, resulting in a response rate of 80.8%. RESULTS: The majority of respondents anticipated discrimination in interpersonal contacts (58%) as well as in the area of employment (55%). The most common experiences of discrimination in interpersonal interactions were the feeling of rejection by other people (87%) and having had an interpersonal contact broken off (50%). Participants living in highly urbanised areas more frequently anticipated exclusion of the mentally ill from the labour market, and older participants more often expressed the view that the mentally ill may have difficulties with access to institutions. The experience of structural discrimination was associated with lower education levels, living in a city, unemployment, being female, and being separated or widowed. The experience of rejection in interpersonal interaction was associated with lower education levels and more hospitalisations, and the experience of a negative public image of the mentally ill with unemployment and more hospitalisations. CONCLUSIONS: (1) In southern Poland, people with schizophrenia both anticipated and experienced the strongest stigma in the domains of interpersonal relationships and employment. (2) Anticipated stigma, contrary to experienced stigma, shows hardly any correlation with patients' specific socio-demographic and clinical characteristics.


Assuntos
Preconceito , Esquizofrenia , Psicologia do Esquizofrênico , Estigma Social , Adolescente , Adulto , Idoso , Antecipação Psicológica , Atitude Frente a Saúde , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polônia , Mudança Social , Fatores Socioeconômicos , Adulto Jovem
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