Detalhe da pesquisa
1.
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Blood
; 141(19): 2372-2389, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580665
2.
Gadd45 in DNA Demethylation and DNA Repair.
Adv Exp Med Biol
; 1360: 55-67, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35505162
3.
BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks.
Nature
; 510(7506): 556-9, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24776801
4.
Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.
J Biol Chem
; 288(10): 7086-95, 2013 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23355489
5.
Interconnected contribution of tissue morphogenesis and the nuclear protein NuMA to the DNA damage response.
J Cell Sci
; 125(Pt 2): 350-61, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331358
6.
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.
Nat Commun
; 15(1): 2862, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580648
7.
Polλ promotes microhomology-mediated end-joining.
Nat Struct Mol Biol
; 30(1): 107-114, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36536104
8.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Mol Cancer Ther
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064712
9.
A protective role for BRCA2 at stalled replication forks.
Breast Cancer Res
; 13(5): 314, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21996371
10.
Polθ promotes the repair of 5'-DNA-protein crosslinks by microhomology-mediated end-joining.
Cell Rep
; 34(10): 108820, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33691100
11.
Polθ reverse transcribes RNA and promotes RNA-templated DNA repair.
Sci Adv
; 7(24)2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34117057
12.
Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition.
Cancer Res
; 80(14): 3033-3045, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193285
13.
Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Nat Commun
; 11(1): 1831, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32273507
14.
Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Nat Commun
; 10(1): 4423, 2019 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31562312
15.
How RNA transcripts coordinate DNA recombination and repair.
Nat Commun
; 9(1): 1091, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545568
16.
Author Correction: Polλ promotes microhomology-mediated end-joining.
Nat Struct Mol Biol
; 30(7): 1048, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059901
17.
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.
Nat Struct Mol Biol
; 22(3): 230-7, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25643323
18.
Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.
Chem Biol
; 22(11): 1491-1504, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26548611
19.
LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Nat Commun
; 6: 8325, 2015 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446488
20.
BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.
Nat Commun
; 4: 2404, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994874