Detalhe da pesquisa
1.
Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.
Immunity
; 50(6): 1530-1541.e8, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31216462
2.
Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J Virol
; 97(5): e0160422, 2023 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37098956
3.
Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J Virol
; 94(13)2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32295908
4.
Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Adv Sci (Weinh)
; : e2309268, 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704686
5.
Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.
J Virol
; 86(22): 12115-28, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22933274
6.
HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep
; 42(7): 112755, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37436899
7.
Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases.
iScience
; 26(8): 107403, 2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37554450
8.
Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies.
J Virol
; 85(9): 4578-85, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325411
9.
Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1.
J Virol
; 85(6): 2524-35, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21191009
10.
Assessment of Crosslinkers between Peptide Antigen and Carrier Protein for Fusion Peptide-Directed Vaccines against HIV-1.
Vaccines (Basel)
; 10(11)2022 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423012
11.
Safety and immunogenicity of an HIV-1 prefusion-stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label, randomized, dose-escalation, phase 1 clinical trial.
EClinicalMedicine
; 48: 101477, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35783486
12.
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J Virol
; 84(16): 8098-110, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20538861
13.
Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSß.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 8): 947-52, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21821902
14.
Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.
Nat Commun
; 12(1): 6470, 2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34753907
15.
A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation.
Vaccine
; 39(25): 3379-3387, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020817
16.
Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature.
Cell Rep
; 32(5): 107981, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755575
17.
Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen.
Sci Rep
; 10(1): 3032, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32080235
18.
Structural studies of E. coli topoisomerase III-DNA complexes reveal a novel type IA topoisomerase-DNA conformational intermediate.
J Mol Biol
; 368(1): 105-18, 2007 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-17331537
19.
Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein.
Protein Sci
; 16(10): 2240-50, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17766373
20.
The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.
J Mol Biol
; 362(2): 259-70, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16904687