Detalhe da pesquisa
1.
SMARCB1 regulates the hypoxic stress response in sickle cell trait.
Proc Natl Acad Sci U S A
; 120(21): e2209639120, 2023 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37186844
2.
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Mol Cell
; 63(3): 485-97, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27425408
3.
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Mol Cell
; 56(2): 205-218, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242145
4.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
EMBO J
; 40(18): e109146, 2021 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34523136
5.
Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer.
Semin Cell Dev Biol
; 64: 98-106, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27615548
6.
Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision.
J Pathol
; 244(5): 525-537, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29266437
7.
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Mol Cell
; 64(2): 431, 2016 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768876
8.
Deadly splicing: Bax becomes Almighty.
Mol Cell
; 33(2): 145-6, 2009 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19187757
9.
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Mol Cell
; 36(3): 487-99, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19917256
10.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
EMBO J
; 31(10): 2322-35, 2012 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510886
11.
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Nature
; 467(7313): 343-6, 2010 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818375
12.
A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.
EMBO J
; 30(16): 3383-96, 2011 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21750527
13.
BAX activation is initiated at a novel interaction site.
Nature
; 455(7216): 1076-81, 2008 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18948948
14.
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
Nat Cell Biol
; 8(12): 1348-58, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17115033
15.
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy.
Proc Natl Acad Sci U S A
; 107(20): 9035-42, 2010 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20418503
16.
Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis.
Nat Commun
; 14(1): 8381, 2023 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38104127
17.
SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.
JCI Insight
; 8(4)2023 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36810256
18.
Combination Therapy With MDM2 and MEK Inhibitors Is Effective in Patient-Derived Models of Lung Adenocarcinoma With Concurrent Oncogenic Drivers and MDM2 Amplification.
J Thorac Oncol
; 18(9): 1165-1183, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37182602
19.
Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy.
Clin Transl Med
; 13(5): e1267, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37226898
20.
Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations.
Nat Cancer
; 4(9): 1345-1361, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37743366