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Pathology ; 18(4): 463-8, 1986 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-2434905

RESUMO

A case of infantile hemangioendothelioma of the liver presenting with congestive heart failure and massive hepatomegaly in a two-mth old baby is described. Serum alpha-fetoprotein was elevated in this patient and clinically the lesion might not be distinguishable from other, commoner hepatic tumours in children. Histologically the tumour showed a type II pattern as defined by Dehner. The significance of classifying this tumour into two histologic types is discussed. Only 3 cases reported in the English literature were studied by electron microscopy; two of them were type I while the other was a type II lesion. In our case the endothelial cells appeared ultrastructurally less differentiated and architecturally more disorganized than in type I lesions. Like the previous case, the basal lamina showed marked thickening and reduplication. The significance of these findings is discussed.


Assuntos
Hemangioendotelioma/ultraestrutura , Neoplasias Hepáticas/ultraestrutura , Membrana Basal/ultraestrutura , Feminino , Hemangioendotelioma/sangue , Hemangioendotelioma/classificação , Humanos , Lactente , Neoplasias Hepáticas/sangue , Neoplasias Hepáticas/classificação , Microscopia Eletrônica , alfa-Fetoproteínas/metabolismo
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