Detalhe da pesquisa
1.
Differential activation states of direct pathway striatal output neurons during L-DOPA-induced dyskinesia development.
J Neurosci
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38664012
2.
PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model.
J Neurophysiol
; 127(1): 86-98, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34788174
3.
Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice.
Neurobiol Dis
; 158: 105454, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333153
4.
Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment.
J Neurosci
; 38(13): 3273-3286, 2018 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29491012
5.
Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus.
Eur J Neurosci
; 45(8): 1102-1110, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28244152
6.
Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus.
J Neurosci
; 35(46): 15276-90, 2015 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586816
7.
PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons.
J Neurosci
; 34(43): 14375-87, 2014 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339750
8.
LRRK2 secretion in exosomes is regulated by 14-3-3.
Hum Mol Genet
; 22(24): 4988-5000, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23886663
9.
Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.
Biochem J
; 453(1): 101-13, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23560750
10.
LRRK2 inhibition attenuates microglial inflammatory responses.
J Neurosci
; 32(5): 1602-11, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22302802
11.
Maturation of GABAergic Synaptic Transmission From Neocortical Parvalbumin Interneurons Involves N-methyl-D-aspartate Receptor Recruitment of Cav2.1 Channels.
Neuroscience
; 513: 38-53, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682446
12.
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations.
Acta Neuropathol Commun
; 11(1): 70, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118844
13.
Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1.
Antioxidants (Basel)
; 11(10)2022 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36290611
14.
Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha.
J Neurosci
; 30(21): 7227-35, 2010 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20505089
15.
Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions.
J Biol Chem
; 285(50): 39087-95, 2010 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20947495
16.
The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic Intervention.
Antioxidants (Basel)
; 11(1)2021 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052512
17.
Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson's Disease.
Front Cell Neurosci
; 15: 626128, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737866
18.
Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities.
Cells
; 10(2)2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33572179
19.
PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons.
Neurochem Int
; 148: 105077, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34082062
20.
Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality.
Brain Commun
; 3(3): fcab208, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34704029