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1.
Mol Biol Evol ; 40(5)2023 05 02.
Artigo em Inglês | MEDLINE | ID: mdl-37071810

RESUMO

Horizontal transfer of transposable elements (TEs) is an important mechanism contributing to genetic diversity and innovation. Bats (order Chiroptera) have repeatedly been shown to experience horizontal transfer of TEs at what appears to be a high rate compared with other mammals. We investigated the occurrence of horizontally transferred (HT) DNA transposons involving bats. We found over 200 putative HT elements within bats; 16 transposons were shared across distantly related mammalian clades, and 2 other elements were shared with a fish and two lizard species. Our results indicate that bats are a hotspot for horizontal transfer of DNA transposons. These events broadly coincide with the diversification of several bat clades, supporting the hypothesis that DNA transposon invasions have contributed to genetic diversification of bats.


Assuntos
Quirópteros , Elementos de DNA Transponíveis , Animais , Elementos de DNA Transponíveis/genética , Quirópteros/genética , Transferência Genética Horizontal , Evolução Molecular , Mamíferos/genética , Filogenia
2.
Science ; 380(6643): eabn1430, 2023 04 28.
Artigo em Inglês | MEDLINE | ID: mdl-37104570

RESUMO

We examined transposable element (TE) content of 248 placental mammal genome assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that although mammals resemble one another in total TE content and diversity, they show substantial differences with regard to recent TE accumulation. This includes multiple recent expansion and quiescence events across the mammalian tree. Young TEs, particularly long interspersed elements, drive increases in genome size, whereas DNA transposons are associated with smaller genomes. Mammals tend to accumulate only a few types of TEs at any given time, with one TE type dominating. We also found association between dietary habit and the presence of DNA transposon invasions. These detailed annotations will serve as a benchmark for future comparative TE analyses among placental mammals.


Assuntos
Elementos de DNA Transponíveis , Eutérios , Evolução Molecular , Variação Genética , Animais , Feminino , Gravidez , Elementos Nucleotídeos Longos e Dispersos , Eutérios/genética , Conjuntos de Dados como Assunto , Comportamento Alimentar
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