Detalhe da pesquisa
1.
A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers.
Proc Natl Acad Sci U S A
; 117(35): 21308-21318, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817551
2.
Non-kinase targeting of oncogenic c-Jun N-terminal kinase (JNK) signaling: the future of clinically viable cancer treatments.
Biochem Soc Trans
; 50(6): 1823-1836, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454622
3.
Mepolizumab decreases tissue eosinophils while increasing type-2 cytokines in eosinophilic chronic rhinosinusitis.
Clin Exp Allergy
; 52(12): 1403-1413, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35475305
4.
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.
Breast Cancer Res
; 21(1): 43, 2019 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30898150
5.
Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
Nature
; 499(7457): 166-71, 2013 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23846654
6.
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.
J Cell Sci
; 129(7): 1340-54, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26872783
7.
Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions.
BMC Bioinformatics
; 15: 305, 2014 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231912
8.
Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically 'actionable' signalling axis in triple negative breast cancer.
bioRxiv
; 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405732
9.
Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism.
Adv Sci (Weinh)
; : e2307963, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602451
10.
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.
Sci Adv
; 9(9): eabp8314, 2023 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36867694
11.
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
J Exp Med
; 220(6)2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36943234
12.
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Nat Cancer
; 4(9): 1326-1344, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640930
13.
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
Sci Adv
; 9(17): eadf9063, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37126544
14.
Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of SerpinE1 and SerpinB2 in cancer.
J Biol Chem
; 286(27): 24467-75, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21606492
15.
Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover.
Cancer Metab
; 10(1): 1, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35033184
16.
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis.
Nat Commun
; 13(1): 4587, 2022 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933466
17.
Personalized Medicine for Neuroblastoma: Moving from Static Genotypes to Dynamic Simulations of Drug Response.
J Pers Med
; 11(5)2021 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34064704
18.
In Vitro 3D Models of Tunable Stiffness.
Methods Mol Biol
; 2294: 27-42, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742392
19.
Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages.
Elife
; 102021 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34967731
20.
A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma.
Elife
; 102021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33983115