Detalhe da pesquisa
1.
A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.
Cell
; 136(5): 939-51, 2009 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19249087
2.
Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.
Nature
; 555(7698): 673-677, 2018 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562231
3.
Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
J Biol Chem
; 298(10): 102401, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988648
4.
An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis.
Mol Ther
; 30(3): 1329-1342, 2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34774753
5.
Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism.
J Immunol
; 202(8): 2451-2459, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850480
6.
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.
Nat Rev Mol Cell Biol
; 9(5): 367-77, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18401346
7.
CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.
J Biol Chem
; 293(44): 17291-17305, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30190322
8.
The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.
J Cell Physiol
; 234(12): 21925-21936, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042012
9.
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
J Biol Chem
; 291(31): 16221-30, 2016 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226575
10.
Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity.
Am J Physiol Endocrinol Metab
; 313(3): E303-E313, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28611026
11.
Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia.
Cardiovasc Diabetol
; 16(1): 87, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28687077
12.
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes.
Nature
; 470(7334): 414-8, 2011 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21331046
13.
The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis.
J Biol Chem
; 290(24): 15175-84, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25922078
14.
Activated Kupffer cells inhibit insulin sensitivity in obese mice.
FASEB J
; 29(7): 2959-69, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805830
15.
Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA.
Mol Pharm
; 13(3): 964-978, 2016 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26815386
16.
Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice.
Proc Natl Acad Sci U S A
; 110(20): 8278-83, 2013 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23630254
17.
Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation.
Nature
; 458(7242): 1180-4, 2009 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19407801
18.
ß3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation.
J Biol Chem
; 288(4): 2882-92, 2013 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23235150
19.
Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance.
Am J Physiol Endocrinol Metab
; 307(4): E374-83, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24986598
20.
Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis.
Elife
; 122024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38564479