Detalhe da pesquisa
1.
Tyrosine Sulfation at Antibody Light Chain CDR-1 Increases Binding Affinity and Neutralization Potency to Interleukine-4.
Int J Mol Sci
; 25(3)2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38339208
2.
Assembly of an activated rhodopsin-transducin complex in nanoscale lipid bilayers.
Biochemistry
; 53(1): 127-34, 2014 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24328127
3.
Exploring Parametric and Mechanistic Differences between Expi293FTM and ExpiCHO-STM Cells for Transient Antibody Production Optimization.
Antibodies (Basel)
; 12(3)2023 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37606437
4.
A potential antibody repertoire diversification mechanism through tyrosine sulfation for biotherapeutics engineering and production.
Front Immunol
; 13: 1072702, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36569848
5.
New Opportunities in Glycan Engineering for Therapeutic Proteins.
Antibodies (Basel)
; 11(1)2022 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35076453
6.
Large-Scale Transient Production in ExpiCHO-S™ with Enhanced N-Galactosylation-Sialylation and PEI-Based Transfection.
Methods Mol Biol
; 2313: 143-150, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478135
7.
Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation.
J Biotechnol
; 360: 79-91, 2022 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36341973
8.
Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin.
Biochemistry
; 50(47): 10399-407, 2011 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21995315
9.
Recent Advances in the Molecular Design and Applications of Multispecific Biotherapeutics.
Antibodies (Basel)
; 10(2)2021 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33808165
10.
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
MAbs
; 13(1): 1850395, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33459147
11.
Automated pH and conductivity conditioning using feedback control to support a two-step continuous purification process.
J Chromatogr A
; 1630: 461537, 2020 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32961387
12.
Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design.
PLoS One
; 15(5): e0232713, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379792
13.
Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins.
Biotechnol Prog
; 35(1): e2724, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30299005
14.
Parallel loading and complete automation of a 3-step mAb purification process for multiple samples using a customized preparative chromatography instrument with networked pumps.
J Chromatogr A
; 1542: 50-60, 2018 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472072
15.
A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.
Brain Res
; 1108(1): 1-11, 2006 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16879811
16.
Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Antibodies (Basel)
; 5(1)2016 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557987
17.
Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.
Biochemistry
; 45(17): 5606-17, 2006 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16634642
18.
Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail.
Mol Pharmacol
; 64(3): 570-7, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12920192