Detalhe da pesquisa
1.
Multimodal small-molecule screening for human prion protein binders.
J Biol Chem
; 295(39): 13516-13531, 2020 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723867
2.
Calibrating from Within: Multipoint Internal Calibration of a Quantitative Mass Spectrometric Assay of Serum Methotrexate.
Clin Chem
; 66(3): 474-482, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32057077
3.
Modeling Small-Molecule Reactivity Identifies Promiscuous Bioactive Compounds.
J Chem Inf Model
; 58(8): 1483-1500, 2018 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29990427
4.
Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases.
Crit Rev Biochem Mol Biol
; 50(1): 31-53, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25365782
5.
Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.
Bioorg Med Chem Lett
; 25(21): 4740-4752, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26318992
6.
Pneumocystis jirovecii Rtt109, a novel drug target for Pneumocystis pneumonia in immunosuppressed humans.
Antimicrob Agents Chemother
; 58(7): 3650-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24733475
7.
Methotrexate-based PROTACs as DHFR-specific chemical probes.
Cell Chem Biol
; 31(2): 221-233.e14, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37875111
8.
Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity.
bioRxiv
; 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961094
9.
Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
Nat Commun
; 14(1): 1364, 2023 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914634
10.
Corrigendum: The promise and peril of chemical probes.
Nat Chem Biol
; 11(11): 887, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26485080
11.
The promise and peril of chemical probes.
Nat Chem Biol
; 11(8): 536-41, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26196764
12.
Corrigendum to "Instability of 7-aminoclonazepam in frozen storage conditions" [Clin. Mass Spectrom. 9 (2018) 23-24].
J Mass Spectrom Adv Clin Lab
; 26: 34, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191162
13.
Addressing Compound Reactivity and Aggregation Assay Interferences: Case Studies of Biochemical High-Throughput Screening Campaigns Benefiting from the National Institutes of Health Assay Guidance Manual Guidelines.
SLAS Discov
; 26(10): 1280-1290, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34218710
14.
The Impact of Assay Design on Medicinal Chemistry: Case Studies.
SLAS Discov
; 26(10): 1243-1255, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34225522
15.
Cross-Platform Bayesian Optimization System for Autonomous Biological Assay Development.
SLAS Technol
; 26(6): 579-590, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34813400
16.
Nuisance compounds in cellular assays.
Cell Chem Biol
; 28(3): 356-370, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33592188
17.
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
ACS Med Chem Lett
; 12(6): 887-892, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141066
18.
The Essential Medicinal Chemistry of Cannabidiol (CBD).
J Med Chem
; 63(21): 12137-12155, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32804502
19.
Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J Med Chem
; 63(6): 2894-2914, 2020 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105470
20.
Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J Med Chem
; 63(9): 4655-4684, 2020 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32118427