Detalhe da pesquisa
1.
Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica.
Mol Cell Proteomics
; 22(12): 100684, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993102
2.
Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins.
PLoS Pathog
; 18(1): e1010226, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007288
3.
Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica.
BMC Genomics
; 23(1): 419, 2022 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35659245
4.
Production of a functionally active recombinant SARS-CoV-2 (COVID-19) 3C-like protease and a soluble inactive 3C-like protease-RBD chimeric in a prokaryotic expression system.
Epidemiol Infect
; 150: e128, 2022 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35723031
5.
Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme.
J Nat Prod
; 85(5): 1315-1323, 2022 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35549259
6.
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver.
BMC Genomics
; 22(1): 46, 2021 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33430759
7.
Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling.
BMC Genomics
; 22(1): 274, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33858339
8.
Antigen-specific response of CD4+ T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep.
Vet Res
; 52(1): 99, 2021 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215335
9.
Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests.
Epidemiol Infect
; 149: e140, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099081
10.
Infection by the Helminth Parasite Fasciola hepatica Requires Rapid Regulation of Metabolic, Virulence, and Invasive Factors to Adjust to Its Mammalian Host.
Mol Cell Proteomics
; 17(4): 792-809, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321187
11.
Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts.
BMC Genomics
; 20(1): 729, 2019 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31606027
12.
Steered molecular dynamics simulations reveal critical residues for (un)binding of substrates, inhibitors and a product to the malarial M1 aminopeptidase.
PLoS Comput Biol
; 14(10): e1006525, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30379805
13.
Proteomic Analysis of Extracellular HMGB1 Identifies Binding Partners and Exposes Its Potential Role in Airway Epithelial Cell Homeostasis.
J Proteome Res
; 17(1): 33-45, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976774
14.
The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.
FASEB J
; 31(1): 85-95, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27682204
15.
Fasciola hepatica Surface Tegument: Glycoproteins at the Interface of Parasite and Host.
Mol Cell Proteomics
; 15(10): 3139-3153, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466253
16.
Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.
J Biol Chem
; 291(37): 19220-34, 2016 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27422822
17.
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis.
Mol Cell Proteomics
; 14(12): 3258-73, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26486420
18.
A vaccine consisting of Schistosoma mansoni cathepsin B formulated in Montanide ISA 720 VG induces high level protection against murine schistosomiasis.
BMC Infect Dis
; 16: 112, 2016 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26945988
19.
A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability.
Exp Parasitol
; 169: 13-21, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27373432
20.
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials.
Trends Biochem Sci
; 35(1): 53-61, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19796954