Detalhe da pesquisa
1.
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Nat Immunol
; 19(9): 942-953, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111894
2.
Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res
; 52(1): 370-384, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994783
3.
Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis.
Cell Mol Life Sci
; 81(1): 227, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38775843
4.
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Mol Cell Proteomics
; 22(3): 100509, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791992
5.
S-palmitoylation determines TMEM55B-dependent positioning of lysosomes.
J Cell Sci
; 135(5)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34350967
6.
LAMP3 deficiency affects surfactant homeostasis in mice.
PLoS Genet
; 17(6): e1009619, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161347
7.
Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein.
Cell Tissue Res
; 392(1): 215-234, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084572
8.
Quantification and characterization of the 5' exonuclease activity of the lysosomal nuclease PLD3 by a novel cell-based assay.
J Biol Chem
; 296: 100152, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288674
9.
Usher syndrome type IV: clinically and molecularly confirmed by novel ARSG variants.
Hum Genet
; 141(11): 1723-1738, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226187
10.
Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.
EMBO Rep
; 21(10): e50241, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929860
11.
Decoding the consecutive lysosomal degradation of 3-O-sulfate containing heparan sulfate by Arylsulfatase G (ARSG).
Biochem J
; 478(17): 3221-3237, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34405855
12.
Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks.
Proc Natl Acad Sci U S A
; 116(16): 7963-7972, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30923110
13.
CLN6 deficiency causes selective changes in the lysosomal protein composition.
Proteomics
; 21(19): e2100043, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34432360
14.
New clinical and molecular evidence linking mutations in ARSG to Usher syndrome type IV.
Hum Mutat
; 42(3): 261-271, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33300174
15.
Characterization of the complex of the lysosomal membrane transporter MFSD1 and its accessory subunit GLMP.
FASEB J
; 34(11): 14695-14709, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959924
16.
Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice.
EMBO Rep
; 20(7): e47055, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31267706
17.
Lysosomal sulfatases: a growing family.
Biochem J
; 477(20): 3963-3983, 2020 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33120425
18.
Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome.
PLoS Genet
; 14(4): e1007363, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698489
19.
A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five.
Neurobiol Dis
; 127: 419-431, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930081
20.
Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.
Hum Mol Genet
; 26(15): 2850-2863, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453791