Bitten by a bug or a bag? Transfusion-transmitted dengue: a rare complication in the bleeding surgical patient.

BACKGROUND: Blood-borne infections remain a risk of blood transfusions. While routine screening of donated blood products has greatly reduced the risk of human immunodeficiency virus, hepatitis B, and hepatitis C transmission, arboviruses such as dengue, chikungunya, and the West Nile virus remain significant risks especially during outbreaks. CASE REPORT: We report a rare case of dengue documented to be acquired through a blood transfusion, which resulted in severe thrombocytopenia prolonging admission in hospital in a neurosurgical patient. RESULTS: The donor of one of the units of red blood cells presented with dengue fever 2 days after donating. Sanger sequencing confirmed DENV-2 (dengue virus, Serotype 2) in both the donor and the patient samples and showed 100% nucleotide sequence identity between the two viruses, confirming transfusion-transmitted dengue infection. CONCLUSION: This case highlights the importance of arboviral screening of donor blood, especially for populations in endemic areas during outbreaks.

A prospective study of surgical outcomes and quality of life in severe foot trauma and associated compartment syndrome after fasciotomy.

The purpose of the present prospective study was to analyze the predictors of outcome and review the quality of life of patients who underwent emergency fasciotomy for foot compartment syndrome after blunt trauma. A total of 14 patients were identified and followed for an average of 24 (range 14 to 33) months. The mean interval from initial presentation to decompressive fasciotomy was 5.8 (range 3 to 11) hours. The follow-up data from our patients revealed satisfactory functional and quality of life outcomes, with 11 of 14 (78.6%) able to return to work. Two (14.3%) patients developed claw-toe deformities and 3 (21.4%) patients had sensory deficits directly attributed to compartment syndrome. Finally, 4 (28.6%) patients required modified shoes or shoe inserts for comfortable ambulation. Our findings suggest that earlier fasciotomy results in better quality of life scores, American Orthopaedic Foot and Ankle Society scale scores, and visual analog scale pain scores and a greater likelihood of being able to wear all shoes comfortably, ambulate independently, and return to work. A shorter interval to fasciotomy, younger age, the absence of bony injury, the absence of other concomitant injuries, and a low velocity crush injury all tended to be predictors of good outcomes at the final review.

Exsanguinators and tourniquets: do we need to change our practice?

PURPOSE: Exsanguinators and tourniquets are regularly used in orthopaedic theatres. A good understanding of their application and contraindications must be ensured to prevent injury to limb or life. However, the level of staff understanding is not well documented. The aims of this study were to assess knowledge of their use between theatre personnel and assess their sterility at our institution. METHODS: A previously published questionnaire was distributed to various orthopaedic theatre personnel responsible for exsanguinator and tourniquet application. Microbiology culture and sensitivity swabs were also taken. RESULTS: Mean questionnaire score for all participants was 30.9%. None of the 74 participants scored more than 49% in the questionnaire. Exsanguinators grew more positive cultures than the tourniquets. CONCLUSIONS: Exsanguinators and tourniquets are used widely in the field of orthopaedics. Lack of their understanding amongst operating theatre personnel involved with their use strongly supports the need for providing and ensuring adequate education to provide the best patient care. In consideration of our findings, we propose a solution addressing these issues.

The efficacy, accuracy and complications of corticosteroid injections of the knee joint.

PURPOSE: Corticosteroid knee injections are being increasingly used in the conservative management of knee osteoarthritis. The procedure is usually performed in secondary care by orthopaedic surgeons and rheumatologists, but as the role of general practitioners in chronic disease management expands, joint injections are now frequently being performed in primary care. It is commonly perceived amongst clinicians that the benefits of corticosteroid knee joint injections in treating symptomatic knee osteoarthritis significantly outweigh the risks of complications. METHODS: The evidence in the literature for the benefits, accuracy, safety and complications of corticosteroid knee injections in osteoarthritis is reviewed. The perception that serious complications are rare is addressed, and the incidence of infectious complications is estimated. RESULTS AND CONCLUSIONS: Short-term symptomatic relief is the only evidence-based benefit of corticosteroid injection of an osteoarthritic knee. Accurate intra-articular placement is not achieved in up to 20% of injections and varies considerably with the anatomical approach used. There is no evidence that a medial approach is more accurate. The incidence of serious infectious complications following knee joint injections ranges widely, and may be as high as 1 in 3,000 and potentially far higher in high-risk patients for whom specialist management is advised.

Anatomic variation of the clavicle: A novel three-dimensional study.

An understanding of the complex anatomy of the clavicle is helpful in the treatment of clavicular fractures. Using three-dimensional (3D) statistical shape analysis, the author presents a novel method to assess geometric morphology of the clavicle. Fifteen fresh frozen shoulder specimens were scanned using high-resolution computerized tomography (CT) but four were excluded from the study. A further 16 high-resolution CT scans of the clavicle were obtained by searching the hospital database. All 27 scans were reconstructed and subsequently imported into and analyzed using a specifically developed statistical software package. Using statistical shape analysis, geometric parameters were then measured. Both gender as well as side specific geometric morphology were observed. Clavicles in men were longer, wider, and thicker than in women. Right clavicles had a greater medial depth than left clavicles, especially in women. Clavicles in men had a greater lateral depth than in women. The sternal angle in women was larger than in men. Using 3D statistical shape analysis and applying it to the clavicle standardizes the study of its anatomy, rules out any variability, and calculates morphological parameters that are accurate, precise, and reproducible. This unique approach provides information that is useful not only to the clinician but also in the modification of current or design of future clavicle fixation devices. More importantly, from an anatomy standpoint, implementation of this novel approach in anatomical studies would eliminate intra- and interobserver variation and allow all studies to be standardized and thus more comparable.

Spaced Education and the Importance of Raising Awareness of the Personal Data Protection Act: A Medical Student Population-Based Study.

BACKGROUND: The Personal Data Protection Act (PDPA) of Singapore was first passed in 2012, with subsequent enforcement regulations effective in 2014. Although medical education via digital platforms is not often used in medical schools in Singapore as of yet, many current means of communication at all levels in the medical community from medical schools to clinics to hospitals are unsecure and noncompliant with the PDPA. OBJECTIVE: This pilot study will assess the effectiveness of MyDoc, a secure, mobile telehealth application and messaging platform, as an educational tool, secure communications tool, and a tool to raise awareness of the PDPA. METHODS: By replacing current methods of communication with MyDoc and using weekly clinical case discussions in the form of unidentifiable clinical photos and questions and answers, we raised awareness the PDPA among medical students and gained feedback and determined user satisfaction with this innovative system via questionnaires handed to 240 medical students who experienced using MyDoc over a 6-week period. RESULTS: All 240 questionnaires were answered with very positive and promising results, including all 100 students who were not familiar with the PDPA prior to the study attributing their awareness of it to MyDoc. CONCLUSIONS: Potential uses of MyDoc in a medical school setting include PDPA-compliant student-to-student and student-to-doctor communication and clinical group case discussions with the sharing of patient-sensitive data, including clinical images and/or videos of hospital patients that students may benefit from viewing from an educational perspective. With our pilot study having excellent results in terms of acceptance and satisfaction from medical students and raising awareness of the PDPA, the integration of a secure, mobile digital health application and messaging platform is something all medical schools should consider, because our students of today are our doctors of tomorrow.

"Publish or perish"-presentations at annual national orthopaedic meetings and their correlation with subsequent publication.

BACKGROUND: Presentation of research at annual national orthopaedic conferences not only serves as a forum for the dissemination of knowledge but is also often a requirement of orthopaedic training programmes. The expected outcome is publication in a peer-reviewed journal. However, publication rates vary for a variety of reasons. The objective of this study was to determine publication rates of presentations from our local Singapore Orthopaedic Association (SOA) annual scientific meeting (ASM) and some of the potential associated factors. We also compared our findings to equivalent meetings worldwide to assess value of scientific content of various orthopaedic conferences. METHODS: All presentations of six SOA ASMs were entered into a database. Using presentation titles, author names and keywords in PubMed and Google Scholar, we determined how many presentations progressed to publication in a peer-reviewed journal. Various comparisons were made to determine factors that could influence publication rates. A comparison with national orthopaedic meetings of America, United Kingdom, Ireland, Australia, Germany, Turkey and Brazil was also conducted. RESULTS: Excluding the ASMs with less than 4 years of follow-up, the publication rate was 35.8%. Both podium and international presenters were found to have significantly higher publication rates than poster and local presenters, respectively, while basic science and clinical research were found to have equivalent rates. Publication rates from other countries' national conferences ranged between 26.6% and 58.1%. CONCLUSIONS: We suggest that the quality of a presentation is related to its subsequent publication in a peer-reviewed journal. Our findings support the general consensus that the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS) is the gold standard for the dissemination of orthopaedic knowledge updates and advancements in our specialty. Each national orthopaedic association could determine the ratio of "presentations at ASM" to "publication within five years of presentation" and use this as a measure of their annual conference's impact on the addition and advancement to the orthopaedic literature. This tool may in turn assist clinicians in determining which meetings to attend.

Postoperative venous thrombotic events in Asian elderly patients with surgically treated hip fractures with and without chemoprophylaxis.

BACKGROUND AND PURPOSE: Chemothromboprophylaxis for hip fracture surgery has been under-practiced in Asia. We investigate the postoperative incidence of venous thrombotic events (VTE) in elderly Asian patients with hip fractures. PATIENTS AND METHODS: Patients over 60 years old with surgically treated hip fractures were reviewed. All patients followed a hip fracture protocol, which included a post-operative ultrasound Doppler venous scan of both lower limbs five days after injury to detect any deep vein thrombosis (DVT). All patients were given mechanical prophylaxis. Patients who had additional chemoprophylaxis were included. RESULTS: From 2010 to 2012, 454 patients were reviewed. The overall incidence of DVT was 6.4% (29 patients). The incidence of PE was 1.3% (six patients). There was no significant correlation between DVT and age, gender, race, hypertension, diabetes mellitus, end stage renal failure, type of fracture and operation, preoperative haemoglobin, platelet count or urea and creatinine levels. Sixteen DVTs (55.2%) were on the ipsilateral side as the fracture, eight (27.6%) were on the contralateral side and five (17.2%) were bilateral. Chemoprophylaxis was not given to 399 patients, of which 27 (6.8%) developed DVT. Ten (2.5%) were proximal DVTs in which four (1%) developed PE. One (0.25%) patient developed PE without DVT. Fifty-five patients were on chemoprophylaxis, of which two (3.6%) developed DVT. Both were proximal DVTs with one subsequently developing PE. CONCLUSIONS: The incidence of VTE in Asian patients may be lower compared to Western populations when mechanical prophylaxis is used. Chemoprophylaxis may assist in reducing the rates of DVT but not PE. The low incidence may not justify the use of routine chemoprophylaxis.

An alternative treatment option for scaphoid nonunion advanced collapse (SNAC) and radioscaphoid osteoarthritis: early results of a prospective study on the pyrocarbon adaptive proximal scaphoid implant (APSI).

INTRODUCTION: Scaphoid nonunion advanced collapse (SNAC) and radioscaphoid osteoarthritis are difficult to treat. Options include proximal row carpectomy (PRC), four corner fusion (4CF) and wrist arthroplasty or arthrodesis. However, with inevitable disease progression, a significant proportion of patients undergo total wrist fusion. This reduces function by abolishing wrist movement. We review the preliminary results of a pyrocarbon interpositional radiocarpal implant in a small cohort of patients from our prospective study and challenge the assumption that there are no surgical alternatives. MATERIALS AND METHODS: This study prospectively studied 12 consecutive pyrocarbon Interpositional arthroplasty day cases over 3 years. Patients were assessed using level of pain, ranges of motion, grip strength, key pinch, type of and time to return to work and the disabilities of the arm, shoulder and hand (DASH) score, both preoperatively and postoperatively. Radiographs were also taken and patient satisfaction recorded. RESULTS: All 12 patients could be contacted and were satisfied with their surgery. There were no immediate, early or late postoperative complications associated with the procedure. Promising results were noted in terms of pain, ranges of motion, grip strength, key pinch, type of and time to return to work, DASH scores, photographs and radiographs. The mean follow-up was 18 months, range between 11 months and 3 years. CONCLUSION: Our early results are encouraging, warrant further and longer studies and support the use of pyrocarbon implants as a primary procedure in what is a generally young and active subgroup of patients.

Accurate intra-articular knee joint injection in the obese? 'Fat Chance!'--A clinical lesson and recommendations for secondary referral.

Corticosteroid joint injections are perceived as being an effective treatment for symptomatic knee osteoarthritis, with a very low risk of complications. While the procedure is often performed in secondary care by orthopaedic surgeons and rheumatologists (and trainees in either specialty), the role of general practitioners (GPs) in chronic disease management has long existed with joint injections also frequently performed in primary care. The perception that serious complications from corticosteroid knee joint injections are rare and that their benefits in treating symptomatic knee osteoarthritis significantly outweigh the risks has not been well addressed. We present a case of a 71-year-old obese female who presented to her general practitioner (GP) with worsening left knee pain and radiographic changes consistent with osteoarthritis. She was administered a corticosteroid joint injection, which gave minimal relief, and over the next few days resulted in worsening severe pain, erythema and swelling. She returned to the GP who commenced oral antibiotics and referred her to casualty. A large knee abscess was diagnosed and intravenous antibiotics were commenced. The patient was admitted under the orthopaedic surgeons with her treatment consisting of multiple surgical procedures over a prolonged duration. Although lengthy, her postoperative recovery was unremarkable. Based on this case report and our review of the literature, we highlight the potential complications associated with corticosteroid knee joint injections and suggest certain patients for whom we would recommend secondary referral before any intervention in primary care.

"Orthobot, to your station!" The application of the remote presence robotic system in orthopaedic surgery in Ireland: a pilot study on patient and nursing staff satisfaction.

The remote presence robotic system (RPRS) enables an individual to "be in two places at once". Its application includes various uses in medicine and surgery. However, its usefulness in the field of orthopaedic surgery has not been described. The objective of our pilot study was to determine patient and nursing staff satisfaction with the RPRS in an orthopaedic clinical setting in Ireland. We performed evening and weekend ward rounds to gain feedback and determine patient and nursing staff satisfaction with this innovative system. Questionnaires were handed to all patients and staff nurses involved. Both patients and nursing staff had very positive reactions to the RPRS in an orthopaedic postoperative care setting. Potential uses in orthopaedic surgery include clinical outreach in the setting of trauma, supervision in theatre, or watching theatre cases from outside the hospital, providing both patient and parent reassurance in paediatric orthopaedic cases, and, finally, in the setting of outpatient departments. Integration of the RPRS in an orthopaedic clinical setting has exciting and limitless potential. More so in this era in which it would allow trainees to benefit from teaching and training while also cutting down their in-house time and thus hospitals costs.

An application of principal component analysis to the clavicle and clavicle fixation devices.

BACKGROUND: Principal component analysis (PCA) enables the building of statistical shape models of bones and joints. This has been used in conjunction with computer assisted surgery in the past. However, PCA of the clavicle has not been performed. Using PCA, we present a novel method that examines the major modes of size and three-dimensional shape variation in male and female clavicles and suggests a method of grouping the clavicle into size and shape categories. MATERIALS AND METHODS: Twenty-one high-resolution computerized tomography scans of the clavicle were reconstructed and analyzed using a specifically developed statistical software package. After performing statistical shape analysis, PCA was applied to study the factors that account for anatomical variation. RESULTS: The first principal component representing size accounted for 70.5 percent of anatomical variation. The addition of a further three principal components accounted for almost 87 percent. Using statistical shape analysis, clavicles in males have a greater lateral depth and are longer, wider and thicker than in females. However, the sternal angle in females is larger than in males. PCA confirmed these differences between genders but also noted that men exhibit greater variance and classified clavicles into five morphological groups. DISCUSSION AND CONCLUSIONS: This unique approach is the first that standardizes a clavicular orientation. It provides information that is useful to both, the biomedical engineer and clinician. Other applications include implant design with regard to modifying current or designing future clavicle fixation devices. Our findings support the need for further development of clavicle fixation devices and the questioning of whether gender-specific devices are necessary.