Detalhe da pesquisa
1.
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies.
Med Res Rev
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530106
2.
Time- and dose-dependent seeding tendency of exogenous tau R2 and R3 aggregates in cells.
Biochem Biophys Res Commun
; 653: 102-105, 2023 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863211
3.
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
Chembiochem
; 22(18): 2741-2761, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33939874
4.
Randomizing for Alzheimer's disease drug trials should consider the cancer history of participants.
Brain
; 146(10): e75-e76, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37243427
5.
Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells.
J Nat Prod
; 81(3): 634-640, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400463
6.
Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease.
Cell Mol Life Sci
; 74(22): 4159-4169, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634681
7.
Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.
Cytometry A
; 91(2): 133-143, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27911980
8.
Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells.
Biochim Biophys Acta Gen Subj
; 1861(7): 1833-1843, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28366502
9.
Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs.
Biochim Biophys Acta
; 1855(2): 172-82, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25662312
10.
Effect of taxoid and nontaxoid site microtubule-stabilizing agents on axonal transport of mitochondria in untransfected and ECFP-htau40-transfected rat cortical neurons in culture.
J Neurosci Res
; 92(9): 1155-66, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24788108
11.
Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond.
Curr Neuropharmacol
; 22(6): 1080-1109, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37898823
12.
Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors.
ChemMedChem
; 19(1): e202300511, 2024 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37916435
13.
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation.
ACS Omega
; 9(7): 8067-8081, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405484
14.
Nucleoside-based anticancer drugs: Mechanism of action and drug resistance.
Biochem Pharmacol
; 215: 115741, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567317
15.
Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation.
Eur J Neurosci
; 35(11): 1705-17, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22594877
16.
Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation.
Biochimie
; 200: 79-86, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35623497
17.
An identification of MARK inhibitors using high throughput MALDI-TOF mass spectrometry.
Biomed Pharmacother
; 146: 112549, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923338
18.
Antitumour drugs targeting tau R3 VQIVYK and Cys322 prevent seeding of endogenous tau aggregates by exogenous seeds.
FEBS J
; 289(7): 1929-1949, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34743390
19.
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs.
Eur J Med Chem
; 243: 114777, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36174412
20.
Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies.
Exp Neurol
; 343: 113756, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33989658