Detalhe da pesquisa
1.
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Cell
; 167(3): 843-857.e14, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720451
2.
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency.
Brain
; 145(12): 4264-4274, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929549
3.
Pharmacological targeting of α3ß4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity.
Diabetologia
; 63(6): 1236-1247, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32140744
4.
Persistent Organic Pollutants in Human Breast Milk and Associations with Maternal Thyroid Hormone Homeostasis.
Environ Sci Technol
; 54(2): 1111-1119, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31867966
5.
Comprehensive analysis of nine monoamines and metabolites in small amounts of peripheral murine (C57Bl/6 J) tissues.
Biomed Chromatogr
; 32(4)2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29166705
6.
Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists.
Bioorg Med Chem Lett
; 25(16): 3157-63, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26099534
7.
Discovery of a new series of [1,2,4]triazolo[4,3-a]quinoxalines as dual phosphodiesterase 2/phosphodiesterase 10 (PDE2/PDE10) inhibitors.
Bioorg Med Chem Lett
; 23(3): 785-90, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23260348
8.
Perinatal effects of persistent organic pollutants on thyroid hormone concentration in placenta and breastmilk.
Mol Aspects Med
; 87: 100988, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238594
9.
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain.
J Pharm Biomed Anal
; 221: 115038, 2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152487
10.
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism.
Sci Adv
; 8(10): eabi4797, 2022 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263141
11.
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1165: 122553, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33503577
12.
Multiple persistent organic pollutants in mothers' breastmilk: Implications for infant dietary exposure and maternal thyroid hormone homeostasis in Uganda, East Africa.
Sci Total Environ
; 770: 145262, 2021 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513488
13.
Detection and quantification of the anti-obesity drug celastrol in murine liver and brain.
Neurochem Int
; 136: 104713, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32151623
14.
Placental distribution of endogenous and exogenous substances: A pilot study utilizing cryo-sampled specimen off delivery room.
Placenta
; 100: 45-53, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32828006
15.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
J Clin Invest
; 130(11): 6093-6108, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32780722
16.
Aging Is Associated with Low Thyroid State and Organ-Specific Sensitivity to Thyroxine.
Thyroid
; 29(12): 1723-1733, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31441387
17.
Association of In Utero Persistent Organic Pollutant Exposure With Placental Thyroid Hormones.
Endocrinology
; 159(10): 3473-3481, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30059991
18.
Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry.
J Chromatogr A
; 1534: 85-92, 2018 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29307529
19.
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
J Med Chem
; 61(24): 11144-11157, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525586
20.
Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.
Diabetes
; 67(11): 2456-2465, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30158241