Detalhe da pesquisa
1.
MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma.
Hum Mol Genet
; 30(24): 2416-2428, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274968
2.
Downregulation of ARID1B, a tumor suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways.
Hum Mol Genet
; 30(18): 1721-1733, 2021 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949667
3.
Downregulation of CRX, a Group 3-specific oncogenic transcription factor, inhibits TGF-ß/activin signaling in medulloblastoma cells.
Biochem Biophys Res Commun
; 568: 76-82, 2021 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34192607
4.
MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma.
Hum Mol Genet
; 30(24): 2524-2525, 2021 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34554250
5.
Restoration of miR-30a expression inhibits growth, tumorigenicity of medulloblastoma cells accompanied by autophagy inhibition.
Biochem Biophys Res Commun
; 491(4): 946-952, 2017 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757413
6.
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Cancer Discov
; 13(11): 2370-2393, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37584601
7.
Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas.
Acta Neuropathol Commun
; 7(1): 52, 2019 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30944042