Detalhe da pesquisa
1.
Discovery of USP7 small-molecule allosteric inhibitors.
Bioorg Med Chem Lett
; 30(20): 127471, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781219
2.
Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands.
ACS Chem Neurosci
; 14(5): 820-828, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780206
3.
Binding of a Pyrene-Based Fluorescent Amyloid Ligand to Transthyretin: A Combined Crystallographic and Molecular Dynamics Study.
J Phys Chem B
; 127(30): 6628-6635, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37477604
4.
Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates.
Bioorg Med Chem Lett
; 22(21): 6721-7, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23010268
5.
Design and synthesis of potent macrocyclic renin inhibitors.
Bioorg Med Chem Lett
; 21(1): 358-62, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21112780
6.
Does a fast nuclear magnetic resonance spectroscopy- and X-ray crystallography hybrid approach provide reliable structural information of ligand-protein complexes? A case study of metalloproteinases.
J Med Chem
; 52(6): 1712-22, 2009 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19239231
7.
Laser-induced fluorescence spectra of 4-methylcyclohexoxy radical and perdeuterated cyclohexoxy radical and direct kinetic studies of their reactions with O2.
J Phys Chem A
; 109(41): 9232-40, 2005 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16833263
8.
Purification, crystallization and preliminary X-ray analysis of the BRCT domains of human 53BP1 bound to the p53 tumour suppressor.
Acta Crystallogr D Biol Crystallogr
; 58(Pt 10 Pt 2): 1826-9, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12351827
9.
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
EMBO J
; 21(14): 3863-72, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12110597