Detalhe da pesquisa
1.
Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.
Haematologica
; 108(5): 1272-1283, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36700399
2.
Rapid screening of COVID-19 patients using white blood cell scattergrams, a study on 381 patients.
Br J Haematol
; 190(5): 718-722, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542672
3.
Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.
Blood
; 129(11): e26-e37, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122742
4.
p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal.
Genes Dev
; 24(13): 1389-402, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20595231
5.
NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia.
Blood
; 124(22): 3274-83, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25316678
6.
Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency.
Haematologica
; 101(10): 1190-1199, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27418650
7.
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.
Nature
; 461(7262): 411-4, 2009 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19727076
8.
Evolution of Artificial Intelligence-Powered Technologies in Biomedical Research and Healthcare.
Adv Biochem Eng Biotechnol
; 182: 23-60, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262750
9.
Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.
Cancer Res
; 79(9): 2339-2351, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862722
10.
CD22low/Bcl-2high expression identifies poor response to inotuzumab ozogamicin in relapsed/refractory acute lymphoblastic leukemia.
Blood Adv
; 7(2): 251-255, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35500285
11.
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Nat Genet
; 47(5): 539-43, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25822087
12.
Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.
Clin Cancer Res
; 20(2): 490-8, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24178622
13.
PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras.
Sci Signal
; 6(304): ra105, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24300897
14.
The genomic landscape of hypodiploid acute lymphoblastic leukemia.
Nat Genet
; 45(3): 242-52, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23334668
15.
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.
Cancer Cell
; 14(4): 335-43, 2008 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18835035
16.
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells.
Blood
; 109(9): 3945-52, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17192389
17.
Abnormal hematopoiesis in Gab2 mutant mice.
Blood
; 110(1): 116-24, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17374739
18.
Beta2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells.
J Cell Sci
; 119(Pt 1): 141-52, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16352660
19.
Membrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol.
J Biol Chem
; 278(31): 29208-15, 2003 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12738795
20.
Targeting oncogenic Ras.
Genes Dev
; 21(16): 1989-92, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17699748