Detalhe da pesquisa
1.
Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.
Cell
; 186(3): 528-542.e14, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36681079
2.
A replication fork determinant for the establishment of sister chromatid cohesion.
Cell
; 186(4): 837-849.e11, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36693376
3.
The Initiation of Eukaryotic DNA Replication.
Annu Rev Biochem
; 91: 107-131, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320688
4.
Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature
; 606(7916): 1007-1014, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705812
5.
Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature
; 575(7784): 704-710, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748745
6.
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication.
Mol Cell
; 65(1): 105-116, 2017 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989442
7.
Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates.
Mol Cell
; 65(1): 117-130, 2017 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989438
8.
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Cell
; 139(4): 719-30, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19896182
9.
The mechanism of eukaryotic CMG helicase activation.
Nature
; 555(7695): 265-268, 2018 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29489749
10.
Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro.
Nucleic Acids Res
; 49(10): 5671-5683, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048583
11.
Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.
Mol Cell
; 55(5): 666-77, 2014 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25087873
12.
Author's overview: identifying SARS-CoV-2 antiviral compounds.
Biochem J
; 478(13): 2533-2535, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198320
13.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase.
Biochem J
; 478(13): 2425-2443, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198323
14.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
Biochem J
; 478(13): 2405-2423, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198322
15.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease.
Biochem J
; 478(13): 2465-2479, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198324
16.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease.
Biochem J
; 478(13): 2517-2531, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198325
17.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease.
Biochem J
; 478(13): 2445-2464, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198326
18.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.
Biochem J
; 478(13): 2481-2497, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198328
19.
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.
Biochem J
; 478(13): 2499-2515, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34198327
20.
Regulated eukaryotic DNA replication origin firing with purified proteins.
Nature
; 519(7544): 431-5, 2015 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25739503