Detalhe da pesquisa
1.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
Cell
; 186(20): 4404-4421.e20, 2023 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774679
2.
Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.
Cell
; 186(20): 4422-4437.e21, 2023 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774680
3.
Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication.
Cell
; 176(4): 816-830.e18, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595451
4.
iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
Glia
; 72(2): 452-469, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969043
5.
Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program.
Mol Cell
; 61(2): 260-73, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26725008
6.
Topologically associating domains are stable units of replication-timing regulation.
Nature
; 515(7527): 402-5, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409831
7.
Topologically associating domains and their long-range contacts are established during early G1 coincident with the establishment of the replication-timing program.
Genome Res
; 25(8): 1104-13, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995270
8.
Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells.
EMBO J
; 31(18): 3678-90, 2012 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22850673
9.
Chromatin-interaction compartment switch at developmentally regulated chromosomal domains reveals an unusual principle of chromatin folding.
Proc Natl Acad Sci U S A
; 109(31): 12574-9, 2012 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22807480
10.
Genome-wide analysis of replication timing in mammalian cells: troubleshooting problems encountered when comparing different cell types.
Methods
; 57(2): 165-9, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22683303
11.
Mapping Replication Timing in Single Mammalian Cells.
Curr Protoc
; 2(1): e334, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34986273
12.
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors.
Cell Stem Cell
; 29(1): 116-130.e7, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995493
13.
Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
Sci Adv
; 8(39): eabo4662, 2022 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170369
14.
Neuronal enhancers get a break.
Neuron
; 109(11): 1766-1768, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34081919
15.
Three-dimensional chromatin organization in brain function and dysfunction.
Curr Opin Neurobiol
; 69: 214-221, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34111830
16.
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq).
J Cell Biol
; 220(12)2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783858
17.
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble.
Nat Neurosci
; 23(12): 1606-1617, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020654
18.
An integrative ENCODE resource for cancer genomics.
Nat Commun
; 11(1): 3696, 2020 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728046
19.
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment.
Stem Cell Reports
; 13(1): 193-206, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31231024
20.
Single-cell replication profiling to measure stochastic variation in mammalian replication timing.
Nat Commun
; 9(1): 427, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382831