Detalhe da pesquisa
1.
ACTIVE (Ability Captured Through Interactive Video Evaluation) workspace volume video game to quantify meaningful change in spinal muscular atrophy.
Dev Med Child Neurol
; 62(3): 303-309, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30963554
2.
First-line ceritinib versus platinum-based chemotherapy in advanced ALK-rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study.
Lancet
; 389(10072): 917-929, 2017 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28126333
3.
KEAP1/NFE2L2 Pathway Signature Outperforms KEAP1/NFE2L2 Mutation Status and Reveals Alternative Pathway-Activating Mutations in NSCLC.
J Thorac Oncol
; 18(11): 1550-1567, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37473958
4.
Inhibition of IL1ß by Canakinumab May Be Effective against Diverse Molecular Subtypes of Lung Cancer: An Exploratory Analysis of the CANTOS Trial.
Cancer Res
; 80(24): 5597-5605, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33023946
5.
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL.
N Engl J Med
; 354(24): 2542-51, 2006 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16775235
6.
Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma.
Clin Cancer Res
; 14(14): 4500-10, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18628465
7.
Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib.
Haematologica
; 93(5): 765-9, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18367481
8.
A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
Clin Cancer Res
; 12(15): 4628-35, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16899611
9.
AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia.
Clin Cancer Res
; 11(13): 4941-7, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16000593
10.
Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies.
J Clin Oncol
; 21(21): 3955-64, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14517187
11.
Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787/ZK 222584.
Semin Oncol
; 30(3 Suppl 6): 32-8, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12802793
12.
Preoperative evaluation for bariatric surgery using transesophageal dobutamine stress echocardiography.
Obes Surg
; 14(7): 948-51, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15329184
13.
Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib.
J Clin Pharmacol
; 53(1): 14-20, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23400739
14.
Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma.
Cancer Chemother Pharmacol
; 69(1): 281-7, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21984222
15.
Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients.
Cancer Chemother Pharmacol
; 69(6): 1507-18, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22392572
16.
Using pharmacokinetic and pharmacodynamic data in early decision making regarding drug development: a phase I clinical trial evaluating tyrosine kinase inhibitor, AEE788.
Clin Cancer Res
; 18(22): 6364-72, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23014528
17.
Phase III study of valspodar (PSC 833) combined with paclitaxel and carboplatin compared with paclitaxel and carboplatin alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary peritoneal cancer.
J Clin Oncol
; 26(16): 2674-82, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18509179
18.
AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells.
Cancer
; 104(6): 1230-6, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16078266
19.
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis.
Blood
; 106(8): 2646-54, 2005 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15994288