Detalhe da pesquisa
1.
Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy.
Cell
; 185(12): 2057-2070.e15, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688133
2.
POINT technology illuminates the processing of polymerase-associated intact nascent transcripts.
Mol Cell
; 81(9): 1935-1950.e6, 2021 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735606
3.
Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence.
Mol Cell
; 72(6): 970-984.e7, 2018 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30449723
4.
Alternative splicing: a pivotal step between eukaryotic transcription and translation.
Nat Rev Mol Cell Biol
; 14(3): 153-65, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385723
5.
How slow RNA polymerase II elongation favors alternative exon skipping.
Mol Cell
; 54(4): 683-90, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24793692
6.
TIMP1 intron 3 retention is a marker of colon cancer progression controlled by hnRNPA1.
Mol Biol Rep
; 47(4): 3031-3040, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200451
7.
The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.
EMBO Rep
; 16(12): 1640-55, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26566663
8.
Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells.
Proc Natl Acad Sci U S A
; 111(44): 15622-9, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313066
9.
Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.
J Biol Chem
; 289(46): 31792-31804, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25239623
10.
Transcriptional elongation and alternative splicing.
Biochim Biophys Acta
; 1829(1): 134-40, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22975042
11.
Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing.
Nat Struct Mol Biol
; 30(10): 1536-1548, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783853
12.
CELF proteins regulate CFTR pre-mRNA splicing: essential role of the divergent domain of ETR-3.
Nucleic Acids Res
; 38(20): 7273-85, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20631008
13.
The c.1275A>G putative chronic pancreatitis-associated synonymous polymorphism in the glycoprotein 2 (GP2) gene decreases exon 9 inclusion.
Mol Genet Metab
; 99(3): 319-24, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19919903
14.
[Kinetic regulation of pre-messenger RNA alternative splicing]. / Régulation cinétique de l'épissage alternatif des pré-ARN messagers: attention au ralentissement.
Med Sci (Paris)
; 30(11): 940-3, 2014 Nov.
Artigo
em Francês
| MEDLINE | ID: mdl-25388571
15.
Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.
Cell Rep
; 18(12): 2868-2879, 2017 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28329680
16.
The RNA Response to DNA Damage.
J Mol Biol
; 428(12): 2636-2651, 2016 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26979557
17.
[Pre-mRNA splicing: when the spliceosome loses ground]. / L'épissage des ARN pré-messagers : quand le splicéosome perd pied.
Med Sci (Paris)
; 32(12): 1103-1110, 2016 Dec.
Artigo
em Francês
| MEDLINE | ID: mdl-28044974
18.
Analysis and Implementation of an Electronic Laboratory Notebook in a Biomedical Research Institute.
PLoS One
; 11(8): e0160428, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27479083
19.
Splicing defects in the CFTR gene: minigene analysis of two mutations, 1811+1G>C and 1898+3A>G.
J Cyst Fibros
; 10(3): 212-6, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21317048
20.
Cotranscriptional exon skipping in the genotoxic stress response.
Nat Struct Mol Biol
; 17(11): 1358-66, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20972445