Detalhe da pesquisa
1.
Modeling the clinical phenotype of BTK inhibition in the mature murine immune system.
J Immunol
; 193(1): 185-97, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899507
2.
B cells regulate neutrophilia during Mycobacterium tuberculosis infection and BCG vaccination by modulating the interleukin-17 response.
PLoS Pathog
; 9(7): e1003472, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23853593
3.
Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis.
J Immunol
; 191(9): 4540-50, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068666
4.
IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice.
J Immunol
; 188(1): 462-9, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131335
5.
IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.
J Immunol
; 188(4): 1656-67, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22231702
6.
Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells.
Eur J Immunol
; 42(6): 1393-404, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22678896
7.
B1 cells promote pancreas infiltration by autoreactive T cells.
J Immunol
; 185(5): 2800-7, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20675587
8.
GM-CSF in the lung protects against lethal influenza infection.
Am J Respir Crit Care Med
; 184(2): 259-68, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21474645
9.
Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys.
Rheumatology (Oxford)
; 50(6): 1033-44, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21258049
10.
Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis.
Bioorg Med Chem Lett
; 21(21): 6258-63, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21958547
11.
The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.
J Immunol
; 181(4): 2799-805, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18684971
12.
Variants within STAT genes reveal association with anticitrullinated protein antibody-negative rheumatoid arthritis in 2 European populations.
J Rheumatol
; 39(8): 1509-16, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753649
13.
Inotuzumab ozogamicin murine analog-mediated B-cell depletion reduces anti-islet allo- and autoimmune responses.
Diabetes
; 61(1): 155-65, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22076927
14.
B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.
PLoS One
; 6(9): e24718, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21931827
15.
Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
J Invest Dermatol
; 131(12): 2428-37, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21881584
16.
Targeting CD22 reprograms B-cells and reverses autoimmune diabetes.
Diabetes
; 57(11): 3013-24, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18689692
17.
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.
J Immunol
; 178(6): 3822-30, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17339481
18.
Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells.
J Biol Chem
; 282(18): 13447-55, 2007 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17355969
19.
B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model.
Blood
; 106(7): 2235-43, 2005 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15947095