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1.
Cureus ; 15(6): e40586, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37469828

RESUMO

A bronchial carcinoid tumor is a rare pulmonary neuroendocrine tumor. This report describes a case where a patient experienced multiple episodes of hemoptysis and dyspnea on exertion over the course of five months. An initial chest X-ray showed an elevated right hemidiaphragm with atelectasis, and a follow-up chest computed tomography (CT) scan was ordered to further assess this finding. The CT revealed a tumor occluding 90% of the right main stem bronchus lumen. A bronchoscopy with biopsy was then performed, confirming the diagnosis of a pulmonary carcinoid tumor. The patient underwent surgical resection of the tumor, a right upper lobe sleeve lobectomy, and a mediastinal lymph node dissection, resulting in full eradication of the tumor. This case highlights the need for physicians to maintain a broad differential when evaluating a patient with hemoptysis and an elevated diaphragm.

2.
Case Rep Ophthalmol ; 13(3): 756-762, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36845450

RESUMO

Testicular cancer is the most common malignancy in men 20-40 years old and most commonly metastasizes to the lung, liver, and brain. Choroidal metastasis from testicular cancer is exceedingly rare, and only few cases have been described in the literature. We report a patient who presented with painful unilateral vision loss as the initial presenting symptom of metastatic testicular germ cell tumor (GCT). A 22-year-old Latino man presented with a 3-week history of progressive central vision loss and dyschromatopsia, accompanied by intermittent, throbbing ocular, and periocular pain, in the left eye. Associated symptom was remarkable for abdominal pain. Examination of the left eye disclosed light perception vision and a large choroidal mass in the posterior pole involving the optic disk and the macula with associated hemorrhages. Neuroimaging showed a 2.1-cm lesion in the posterior globe of the left eye, and B-scan and A-scan ultrasonography findings were consistent with choroidal metastasis. Systemic workup revealed a mass in the left testicle with metastasis to the retroperitoneum, lungs, and liver. Biopsy of a retroperitoneal lymph node showed a GCT. Visual acuity worsened from light perception to no light perception 5 days following initial presentation. Several cycles of chemotherapy were completed, including salvage therapy; however, these treatments were unsuccessful. While vision loss due to choroidal metastasis as the initial presenting symptom of testicular cancer is rare, clinicians should consider metastatic testicular cancer in the differential diagnoses in patients with choroidal tumors, especially in young men.

3.
Brain Sci ; 12(5)2022 Apr 30.
Artigo em Inglês | MEDLINE | ID: mdl-35624973

RESUMO

A growing body of research documents the persistence of physical and neuropsychiatric symptoms following the resolution of acute COVID-19 infection. To the best of our knowledge, no published study has examined the interaction between insomnia and mental health. Accordingly, we proposed to examine new diagnoses of insomnia, and referrals to pulmonary and sleep medicine clinics for treatment of sleep disorders, in patients presenting to one post-acute COVID-19 recovery clinic. Additionally, we aimed to examine the relationship between poor sleep quality, depression, anxiety, and post-traumatic stress. Patients presented to the clinic on average 2 months following COVID-19 infection; 51.9% (n = 41) were hospitalized, 11.4% (n = 9) were in the intensive care unit, 2.5% (n = 2) were on a mechanical ventilator, and 38.0% (n = 30) were discharged on oxygen. The most commonly reported symptom was fatigue (88%, n = 70), with worse sleep following a COVID-19 infection reported in 50.6% (n = 40). The mean PSQI score was 9.7 (82.3%, n = 65 with poor sleep quality). The mean GAD-7 score was 8.3 (22.8%, n = 14 with severe depression). The mean PHQ-9 was 10.1 (17.8%, n = 18 with severe anxiety). The mean IES-6 was 2.1 (54.4%, n = 43 with post-traumatic stress). Poor sleep quality was significantly associated with increased severity of depression, anxiety, and post-traumatic stress. Future work should follow patients longitudinally to examine if sleep, fatigue, and mental health symptoms improve over time.

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