Detalhe da pesquisa
1.
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Proc Natl Acad Sci U S A
; 119(15): e2109617119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353605
2.
Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional Study.
Int J Mol Sci
; 25(4)2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396924
3.
Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study.
Int J Mol Sci
; 24(8)2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108604
4.
Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia.
Int J Mol Sci
; 24(9)2023 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175824
5.
α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.
Brain
; 143(1): 249-265, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31816026
6.
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.
Brain
; 143(5): 1462-1475, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32380543
7.
Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity.
Molecules
; 26(12)2021 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205249
8.
Antibodies against alpha-synuclein: tools and therapies.
J Neurochem
; 150(5): 612-625, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31055836
9.
Parkinson's disease biomarkers based on α-synuclein.
J Neurochem
; 150(5): 626-636, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265130
10.
Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease.
Neurobiol Dis
; 127: 163-177, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30849508
11.
Corrigendum to " Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy Body Disease" [Neurobiology of Disease127 (2019) 163-177].
Neurobiol Dis
; 191: 106397, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216383
12.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Neurobiol Dis
; 130: 104525, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276792
13.
Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson's disease.
BMC Neurol
; 19(1): 113, 2019 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31164098
14.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
15.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
16.
α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies.
Mov Disord
; 33(11): 1724-1733, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30440090
17.
Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice.
Brain
; 139(Pt 3): 856-70, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719384
18.
Glycation in Parkinson's disease and Alzheimer's disease.
Mov Disord
; 31(6): 782-90, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26946341
19.
Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression.
Mov Disord
; 31(10): 1535-1542, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548849
20.
Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.
Neurobiol Dis
; 78: 100-14, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25818009