Detalhe da pesquisa
1.
Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface.
Genes Dev
; 37(11-12): 518-534, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442580
2.
Post-translational modifications within tau paired helical filament nucleating motifs perturb microtubule interactions and oligomer formation.
J Biol Chem
; 298(1): 101442, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838590
3.
Molecular and functional interactions of alpha-synuclein with Rab3a.
J Biol Chem
; 298(9): 102239, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809645
4.
Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM.
J Am Chem Soc
; 145(15): 8583-8592, 2023 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37023263
5.
Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog.
Nat Chem Biol
; 16(9): 1006-1012, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514183
6.
Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau.
J Biol Chem
; 295(23): 7905-7922, 2020 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341125
7.
Chemoenzymatic Semi-synthesis Enables Efficient Production of Isotopically Labeled α-Synuclein with Site-Specific Tyrosine Phosphorylation.
Chembiochem
; 22(8): 1440-1447, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33274519
8.
Intrinsically disordered proteins in synaptic vesicle trafficking and release.
J Biol Chem
; 294(10): 3325-3342, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700558
9.
3-O-Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake.
Angew Chem Int Ed Engl
; 59(5): 1818-1827, 2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31692167
10.
Structural basis of sterol binding and transport by a yeast StARkin domain.
J Biol Chem
; 293(15): 5522-5531, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463678
11.
A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils.
Biophys J
; 114(12): 2811-2819, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925018
12.
Exploring the role of methionine residues on the oligomerization and neurotoxic properties of DOPAL-modified α-synuclein.
Biochem Biophys Res Commun
; 505(1): 295-301, 2018 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249394
13.
Glycan Determinants of Heparin-Tau Interaction.
Biophys J
; 112(5): 921-932, 2017 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28297651
14.
Structural basis for recognition of diubiquitins by NEMO.
Mol Cell
; 33(5): 602-15, 2009 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19185524
15.
Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of α-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).
J Biol Chem
; 290(46): 27660-79, 2015 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26381411
16.
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
Hum Mol Genet
; 23(11): 2858-79, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412932
17.
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.
Hum Mol Genet
; 23(17): 4491-509, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24728187
18.
STARD4 Membrane Interactions and Sterol Binding.
Biochemistry
; 54(30): 4623-36, 2015 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26168008
19.
N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.
J Biol Chem
; 289(6): 3652-65, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338013
20.
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity.
J Biol Chem
; 289(32): 21856-76, 2014 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24936070